"The susceptibility and severity of is made more severe by diabetes, with the impact on the disease process inversely proportional to the level of glycemic control. Although type 1 diabetes mellitus and type 2 diabetes mellitus have different etiologies, and their impact on bone is not identical, they share many of the same complications. Studies in animals and humans agree that both forms of diabetes increase inflammatory events in periodontal tissue, impair new bone formation, and increase expression of in response to bacterial challenge. High levels of glucose, reactive oxygen species, and advanced glycation end-products are found in the periodontium of diabetic individuals and lead to increased activation of nuclear factor-kappa B and expression of inflammatory cytokines such as tumor necrosis factor and interleukin-1. Studies in animals, moreover, suggest that there are multiple cell types in periodontal tissues that are affected by diabetes, including leukocytes, vascular cells, mesenchymal stem cells, periodontal ligament fibroblasts, osteoblasts, and osteocytes."
Quote Details
Added by wikiquote-import-bot
Unverified quote
0 likes
Original Language: English
Available Languages (1)
Sources
Dana T. Graves, Zhenjiang Ding, and Yingming Yang,
https://en.wikiquote.org/wiki/Diabetes
Revision History
No revisions have been submitted for this quote.
Categories
Diabetes
7 quotes on TrueQuotesView all quotes by Diabetes →
Related Quotes
"On October 30th, 1920, I was attracted by an article by , in which he pointed out the similarity between the degenera…"
"Even for most of us who spend our time working in the field of experimental diabetes, the primary concern is the diso…"
"The modern era of diabetes knowledge began with the accidental discovery by a European research physiologist, , that …"
"Believing that the want of success to prepare extracts of uniform potency as due to the destruction of the antidiabet…"
"Evidence from observational studies and randomized trials suggests that prediabetes and type 2 diabetes mellitus (T2D…"
"Type 2 diabetes accounts for almost 90% of all cases of diabetes in adults worldwide. In general, as countries become…"
"Carbuncle is a confluent folliculitis that is affecting multiple s leading to multiple sinuses discharging pus. Optim…"
"He continued at work until March, 1853, when he had an accident—a fall while descending some steps. A few weeks later…"
"When the cook came in he was in a bad mood. He had a developing carbuncle on the back of his neck and the skin from t…"
"The starting-point of this lecturing trip around the world was Paris, where we had been living for a year or two. We …"