"[about to kill Beavis and Butt-head when he realized he mistook them for hitmen after he found them in the desert] I'm gonna blow you both to Hell, that's what I'm gonna do!"

"[about to kill Beavis and Butt-head when he realized he mistook them for hitmen after he found them in the desert] Oh, I'm gonna enjoy this. Any last words before I kill you?"

"Let me tell you something about over there. It hurts over there. It's lonely over there. It's a war over there. They got 8 million ways for you to die on and they're all permanent. This is real for me, this with you. If I want to stay with you, I gotta go back."

"Gregory Snegoff as Bash"

"Patrick Pinney as Chico the bouncer"

"Candi Milo as Lonette/Bob"

"Maurice LaMarche as Interrogator No. 2/Mash/ Dr. Vincent "Vegas Vinnie" Whiskers/Super Jack. LaMarche also makes a cameo live-action appearance sitting at a bar."

"Michael Lally as Sparks"

"Jenine Jennings as Craps Bunny"

"Joey Camen as Interrogator No. 1/Slash/Holli's Door"

"Charlie Adler as Nails, an anthropomorphic spider who serves as Frank's partner. He actually has four arms and two legs."

"Kim Basinger as Holli Would, a femme fatale doodle who wishes to be real in the real world. Basinger also portrays her in live action."

"Marilyn Monroe (archival footage)"

"Janni Brenn–Lowen as Agatha Rose Harris"

"Michele Abrams as Jennifer Malley"

"Frank Sinatra, Jr. as Himself"

"Deirdre O'Connell as Isabelle Malley"

"Brad Pitt as Detective Frank Harris, a detective for the Cool World Police Department who is bent on catching Holli. Brad Pitt also provides Frank's voice in doodle form."

"Gabriel Byrne as Jack Deebs, the cartoonist seemingly responsible for the creation of Cool World."

"Holli Would if she could ...and she will."

"There are two different worlds: The Real World and the Wacky, Animated World. Only one of them will survive."

"Cool World is such a dangerous place to be in."

"Audiences actually wanted a wilder, raunchier Cool World. The premiere audience I saw it with certainly did."

"I'm made of ink, but I'm no dream."

"Can't let the neighbors push us around can."

"I know that movie by heart. The girl gets everything by the end of it everything she every wanted."

"Well, howdy, Nails. As you see, there have been some changes around here. [Nails: You made out with a noid, you don't know what you are! Mark my words, girlie-pie! You leave here and it is trouble for you!] I'm leaving, pencil-dick! You just try and stop me!"

"You want to know what it is about you that really kicks my ass, Harris?"

"Don't you get it? They're real. When they touch someone, they feel it. When they taste something, they REALLY taste it. And when they are... With a man! Woo!"

"You know, sweetheart, you look good in flesh. It's almost a shame I gotta take you back. You are going back, you know?"

"You do nothing, man. This place exists with or without you. You believe me, right? I'm not one of your creations."

"Noids do not have sex with doodles. Right? Noids do not have sex with doodles!!"

"You've had enough of me? You've had enough of me, you piece of shit? You screwed us all for a piece of ass? And you've had enough of me? Where is she? It's the oldest law in Cool World. I've never had to enforce it. You cross that line, I'll slap you around and make you piss like a puppy."

"Wouldn't YOU Like a Good Duck Tonight?"

"Any resemblance to ducks living or dead is purely coincidental."

"Madder Than Daffy. Dumber Than Donald. More Existential Than Howard!"

"You can't do this to me! I was at Woodstock in '69! I saw 200 MOTELS! I know who I am!"

"Walker Edminston — Bus Driver / Jail Orator / Small Fag / Prospector / Mexician Official / President / Man in Elevator"

"Cynthia Adler — Lady in Car / Boss Lady / Small Dyke / Lady in Elevator"

"Robert Ridgely — Car Salesman / Man at Bus Stop / Negro Gentleman / Big Fag / Police Officer / Tank"

"Mark Volman — Duck / Side Hack Rider"

"Howard Kaylan — Willard / Nego Lady / Side Hack Rider"

"An adult "Cult Classic" that's a Quack-Up!"

"Mom: Ugh, if only I had all the money in the world...oh wait a second, I do! [cackles madly]"

"Calculon: I'd like to thank the Academy, my agent, and most of all, my operating system, Windows Vista ['Windows' 7 for network release] for everything...[begins malfunctioning] System Error!"

"Leo Wong: [as Fry massages his feet] Ooh, that nice. Get between the toes, very dirty."

"Clamps: The clamps! Or a clamp-like device."