"This is the Alpha and Omega bomb. It can destroy not only Ape City, but the entire Earth. Activate it and we become nothing. Leave it and its very presence will ensure that at least we remain something, and may become something better. It must never be exploded. It must be respected, even venerated, for one of its ancestors made us what we are. And what we are shall, from this day forward, be called beautiful."

"Governor, somewhere along the line of history, this bloody chain reaction has got to stop! A destroys B. B destroys C. C destroys A and is destroyed by D who destroys E. Before anyone knows where they are, there won't be anyone left to know anything, anywhere!"

"And so, Mandemus, we must be patient...and wait."

"We...want...guns! Guns...are...power! Now we go and get guns!!"

"This is Susan Murphy, saying, "Goodbye, Derek!""

"There were definitely some disorienting moments where I had no idea what was going to happen with her. I remember one day I came in and we’d had like ten recording sessions and I said ‘how does this movie end? Do I die?’ I didn’t know what was going to happen and they’re like ‘oh, right. We never told you what the third act was’ (after the San Francisco chase scene). Where are we going to go from here? Then I found out there were a whole two acts after that. We worked on the first act so much to get it right."

"I think the main thing, for me, was finding a female character that I felt like really spoke to young women and that was really important to me. I didn’t want to be somebody’s girlfriend. Not to say that those roles aren’t as good but I loved the idea of this character being pro-active and driving her own story, changing her own life through her own will. That’s such a great message for young women and I’m so excited to be doing that and also, it brings the energy to the party. I’d go in there with such enthusiasm and excitement to be a part of something like that."

"Jeffrey Katzenberg — Moon Boy"

"Anne Lockhart — Girl Screaming In The Car"

"Bridget Hoffman — Girl Screaming In The Car"

"Ed Helms — News Reporter"

"John Krasinski — Cuthbert"

"Renée Zellweger — Katie"

"Julie White — Wendy Murphy"

"Jeffrey Tambor — Carl Murphy"

"Paul Rudd — Derek Dietl"

"Stephen Colbert — President Hathaway"

"Kiefer Sutherland — General Warren R. Monger"

"Reese Witherspoon — Susan Murphy/Ginormica"

"Amy Poehler — Gallaxhar's Computer"

"Rainn Wilson — Gallaxhar"

"Frank Welker — Insectosaurus"

"Hugh Laurie — Dr. Cockroach, PhD"

"Seth Rogen — B.O.B."

"Will Arnett — The Missing Link"

"Saving the day the monster way."

"When aliens attack, these guys got your back."

"Ooze gonna save us?"

"When aliens attack, monsters fight back"

"Alien problem? Monster solution."

"Announcer: Channel 172."

"TV Reporter: Once again, a UFO has landed in America - the only country UFOs ever seem to land in!"

"Derek Dietl: [rejecting Susan] Don't crush me for saying this, but I'm not looking to get married and spend the rest of my life in someone else's shadow. And you're casting a pretty big shadow."

"Wedding Guest: [after Susan grows to her massive height] Here comes the bride!"

"Uh, honey, ever since you were a little baby, I knew that someday... you would save the world from an alien invasion from outer space."

"[as Bob spits her out] I taste ham."

"Oh, Carl. It's her wedding day!"

"Jerry, stop it! Let me calculate its impact point. Looks like... Modesto, California."

"Wow, its energy signature is massive."

"Hey, Jerry, you wanna check this one out. Uh, Palomar just picked up... Looks like some type of UFO and it's heading this way."

"Supernova, this is Red Dwarf! We actually have one! Code Nimoy! I repeat! CODE NIMOY!!!!!!!!!!!!"

"Holy Cheez-Its! What do we do?! No one ever told us what to do! THE ONLY REASON I TOOK THIS JOB IS BECAUSE YOU NEVER HAVE TO DO ANYTHING!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!"

"How many times do I have to tell you this? UFOs don't exist, and we're never gonna see..."

"Okay, someone set the terror level to Code Brown, because I need to change my pants!"

"[after Monger gives a cabinet member a wedgie] Okay! [hides behind his chair] Stay where you are. General, I propose we go forward with your "monsters vs. aliens" idea... thingy."

"Listen up! I'm not going to go down as the President who was in office when the world came to an end, so somebody think of something, and think of it fast! [sips coffee] That is a good cup of joe."

"So, that's how you wanna play it? Eat lead, alien robot! [fires three shots; the robot is heard munching on them] Evidently, they eat lead. Huh. [to a crowd] I am brave! I am a brave President!"