"[from trailer] It is not an offspring of witchcraft or Satan. It was created by man. It will grow to be 15 feet tall. It will have huge eyes, webbed hands, hooked claws. It will walk upright. And it will mindlessly, mercilessly, kill every living thing it meets."

"She Lives. Don't Move. Don't Breathe. She Will Find You."

"The environment is us. And it's being mangled. And I'm gonna make something very clear to you. My people are violently ill. They're beginning to lose their faculties. They stagger and they fall, and this has nothing to do with alcohol, as these villagers claim. My people are fishermen; their lives are clean."

"Mia Bendixsen - Kathleen Nelson"

"This camp is as the old people did it. I'm teaching these young people so that someone here will remember. There are underground tunnels beneath the frost line to store perishables. The forest provides more food than a man could possibly need. Here, everything grows big—real big."

"[from TV spot] She is alive and will grow to be 15 feet tall. With teeth and talons that are razor sharp, with flesh twisted and warped. She will kill. She will find you."

"Inorganic methylmercury, known as PMT, used as a desliming agent that collects algae and prevents it from forming on preprocessed timber. Its widespread use discontinued in 1956 when evidence of its fatal effects... were seen in the deaths of 100,000 people in Minamata, Japan."

"[from the tape recorder] Described as the most potent neurotoxin of the post-World War II age. Used from 1948 to 1956 in pulping processes as a cheap and effective caustic agent that prevents algae from forming on waterlogged timber. It is also known for its mutagenic properties, concentrating in the bodies of fish and plankton-eating crustacea, affecting the fetal development of everything that ingests it. The ratio of toxin to blood level is 30% higher in the developing fetus than in the host. It was discovered, after extensive testing, that it is the only mutagen that jumps the placental barrier, concentrating in fetal blood cells, where it adheres to the DNA and corrupts the chromosomes."

"Frank Welker - the voice of Katahdin"

"I'm gonna tell you right now!! You cut my head off before you cut these trees!!"

"Kevin Peter Hall - Katahdin"

"Tom McFadden - Huntoon"

"Charles H. Gray - Sheriff Bartholomew Pilgrim"

"Graham Jarvis - Victor Shusette"

"A developing fetus goes through certain distinct phases. Each phase represents a specific stage of evolution. A human fetus, for instance. At one stage, it's a fish. It looks like a fish; it's got fins and gills. At another, it's amphibian—webbed hands; at another, reptilian; at another, it's feline—developing upward in the distinct shapes and phases of the evolutionary scale. If this chemical, methylmercury, adheres to the DNA—DNA's a chromosomal fixative—it could freeze certain parts at one evolutionary stage, while the other parts continue growing. A pregnant animal ingests the fish, and it corrupts the fetus to a point where it gives birth to a monster."

"Johnny Timko - Paul Nelson"

"Everett Creach - Kelso"

"Ricky Garcia as Frank"

"Wallace Shawn as Dr. Christian Burr"

"Jim Norton as Hank"

"Rob Riggle as Riggs (uncredited)"

"Patrice O'Neal as Gus"

"Matt Prokop as Tyler Sanders, Dan & Tammy’s son"

"Ken Jeong as Neil Lyman, Dan’s evil boss"

"Angela Kinsey as Felder, Neil’s assistant"

"Brooke Shields as Tammy Sanders, Dan’s wife"

"Toby Huss as Wilson"

"Brendan Fraser as Dan Sanders"