"[On] Titan, Saturn's giant moon . . . the seas and the rain are made not of water but of methane and ethane. . . . [W]e can imagine other kinds of life. There might be creatures that inhale hydrogen instead of oxygen. And exhale methane instead of carbon dioxide. They might use acetylene instead of sugar as an energy source."
January 1, 1970
https://en.wikiquote.org/wiki/Cosmos%3A_A_Spacetime_Odyssey