"... More explicitly than ever before the modern principles of physical science seem to compel us to recognized absolute mechanical necessity in all things. We may not understand organic regulations, or organic evolution, or the origin of life; in fact we are still unable with the necessary clearness to represent to ourselves the structure of a cell; yet theses are at least phenomena. As phenomena they are subject to the two laws of thermodynamics. For the laws of conservation and degradation of energy have long since supplanted Leibniz's rudimentary idea of the conservation of ', as the ground of our conception of necessary causation."