"Dr. Luc Montagnier: [In French] It's amazing to me that Americans can think a disease has a sexual preference. But that's all Americans think of... Sex. Sex. Sex."

"Congressman Phil Burton: I'll introduce a bill. But if all the angels came dancing down to earth like the Rockettes, even they couldn't get a dime out of this administration for anything with the name "gay" on it."

"Roger Gail Lyon: This is not a political issue. This is a health issue. This is not a gay issue. This is a human issue. And I do not intend to be defeated by it. I came here today in the hope that my epitaph would not read that I died of red tape."

"Dr. Dennis Donohue: When the doctors start acting like businessmen, who do the people turn to for doctors?"

"The Choreographer: The party's over."

"Dr. Jim Curran: All right, what do we think? What do we know? What can we prove?"

"This may be the first epidemic in history of which no one officially died."

"Keone Young as Dr. Lin"

"Allan Rich as Dr. Benfante"

"Michael McKean as Paulie"

"Mario Yedidia as George"

"Seth Smith as John-John"

"Todd Bosley as Eddie"

"Adam Zolotin as Louie Durante"

"Bill Cosby as Lawrence Woodruff"

"Fran Drescher as Dolores "D.D." Durante"

"Brian Kerwin as Brian Powell"

"Jennifer Lopez as Miss Elena Marquez"

"Diane Lane as Karen Powell"

"Robin Williams as Jack Powell"

"I want to be just like my best friend when I grow up. He's only ten but he looks much older. He's like the perfect grown up because on the inside, he's still just a kid - he's not afraid to learn things or try things, or to meet new people the way most grown ups are. It's like he's looking at everything for the first time - because he is. And most grown ups aren't like that."

"[his speech at the graduation] I don't have very much time these days, so I'll make it quick. Like my life. You know as we come to the end of this phase of our lives, we find ourselves trying to remember the good times and trying to forget the bad times, and we find ourselves thinking about the future. We start to worry, thinking "What am I gonna do?", "Where am I gonna be in ten years?". But I say to you, "Hey, look at me". Please, don't worry so much, because in the end, none of us have very long on this earth - life is fleeting. And if you're ever distressed, cast your eyes to the summer sky when the stars are strung across the velvety night, and when a shooting star streaks through the blackness turning night into day, make a wish and think of me. Make your life spectacular. I know I did. I made it, mom! I'm a grown up."

"Isabella Rossellini - Lisle Von Rhoman"

"Bruce Willis — Dr. Ernest Menville"

"Meryl Streep — Madeline Ashton"

"Goldie Hawn — Helen Sharp"

"In one small bottle... The fountain of youth. The secret of eternal life. The power of an ancient potion. Sometimes it works... sometimes it doesn't."

"Some people will go to any lengths to stay young forever. But Madeline Ashton and her old friend Helen Sharp are about to go TOO far."

"This is life's ultimate cruelty. It offers us a taste of youth and vitality, and then it makes us witness our own decay."

"Make some room for my friend, for Christ's sake. But... keep your ass handy."

"(Last lines. Helen and Madeleine shatter into pieces after falling down stairs) Do you remember where you parked the car?"

"En garde, BITCH!"

"Divorce? In California? That is exactly what she wants you to do. You have no talent for poverty."

"(while confronting Ernest Menville) No Ernest, she has wasted you, she married a brilliant surgeon and turned him into an undertaker. I want you to know something, I have never blamed you for leaving me. I always knew it was her. She is a woman, Ernest, a woman, from Newark, for God's sake. I will never forgive her for what she has done to you. Never."

"(while confronting Madeline Ashton) Listen, that was a long time ago, you didn't steal him, he went to you. It wasn't you, it was him. I just want you to know something that I have never ever blamed you, never."

"She was a homewrecker, she was a man eater, and she was a bad actress."

"(whilst peering through a gaping hole in Helen) You're a fraud, Helen. A walking lie and I can see right through you."

"And she even paid for the hardware. Don't you just love it?"

"Ernest! You pushed me down the stairs."