"Tim Minear: She had this magic syringe. She would take this drug. And if she were, for instance, raped, the rapist would die a horrible death. The story was that she gets kidnapped by Reavers and when Mal finally got to the ship to save her from the Reavers, he gets on the Reaver ship and all the Reavers are dead. Which would suggest a kind of really bad assault. At the end of the episode, he comes in after she's been horribly brutalized, and he comes in and he gets down on his knee, and he takes her hand. And he treats her like a lady. And that's the kind of stuff that we wanted to do. It was very dark. And this was actually the first story that Joss pitched to me when he asked me to come work on the show. He said, 'These are the kind of stories we're going to do.'"

"Every story needs a monster. In the stories of the old west it was the Apaches. I used that example by saying that anyone who goes out into space and goes mad can become a monster."

"This show isn't about the people who made history; it's about the people history stepped on."

"People watch Firefly and they think, boy you guys must have a lot of fun there, you must have a great time, the high jinks that ensue. Well, the truth is, there are no high jinks, we're absolutely serious. We're very professional and we never, ever make mistakes. [fumbles with camera] How'dya turn this fuckin' thing off?"

"Nothing like a movie deal to make you feel better about your TV show getting cancelled!"

"So here's what I have to say about Serenity: This is the kind of movie that I have always intended Ender's Game to be (though the plots are not at all similar). And this is as good a movie as I always hoped Ender's Game would be. And I'll tell you this right now: If Ender's Game can't be this kind of movie, and this good a movie, then I want it never to be made. I'd rather just watch Serenity again."

"And I wanted to say "Hi" to all the Firefly flans in— "flans"? I wanted to say "Hi" to all you Firefly flans out there. You flans are the best flans a… actor could ever hope for. Keep being a good flan!"

"So I wanted to get a show that took the past and the future, and put them together by making them feel like the present…"

"Take me out To the black Tell them I ain't coming back Burn the land And boil the sea You can't take the sky from me."

"There's no place I can be Since I found Serenity But you can't take the sky from me."

"Take my love Take my land Take me where I cannot stand I don't care I'm still free You can't take the sky from me."

"Alan Tudyk — Hoban "Wash" Washburne"

"Gina Torres — Zoe Alleyne Washburne"

"Jewel Staite — Kaywinnit Lee "Kaylee" Frye"

"Sean Maher — Dr. Simon Tam"

"Frank Conniff — TV's Frank (1990–1995)"

"Mark Hamill - P.T. Mindslap (2017)"

"Jerry Seinfeld - Freak Masterstroke (2017)"

"Neil Patrick Harris – Neville Laroy (2017)"

"Leonard Maltin - Himself (1998)"

"Kelsey Ann Brady — Crow T. Robot (2022)"

"Emily Marsh — Emily Connor, (2022)"

"Rebecca Hanson – Gypsy/Synthia Forrester (2017–2022)"

"Patton Oswalt — Max, TV’s Son of TV’s Frank (2017–2018)"

"Felicia Day — Kinga Forrester (2017–2018)"

"Hampton Yount — Crow T. Robot (2017–2018)"

"Baron Vaughn — Tom Servo (2017–2018)"

"Jonah Ray — Jonah Heston (2017–2018)"

"Patrick Brantseg — Gypsy (1997–1999)"

"Bill Corbett — Crow T. Robot/Observer (1997–1999)"

"Mary Jo Pehl — Pearl Forrester (1994) (1996–1999)/Magic Voice (1992–1994)"

"Michael J. Nelson — Mike Nelson (1993–1999)/Jack Perkins (recurring)"

"Jim Mallon — Gypsy (1989–1997)"

"Kevin Murphy — Tom Servo (1990–1999)/Professor Bobo (1997–1999)/Cambot (1988)"

"Trace Beaulieu — Crow T. Robot/Dr. Clayton Forrester (1988–1996, Turkey Day 2014)"

"Josh Weinstein — Tom Servo/Dr. Laurence Erhardt (1988–1989)/Gypsy (1988)"

"Joel Hodgson — Joel Robinson (1989–1993) (1999) (2022)/Joel Hodgson (1988)"

"Kristine Kochanski, a version of Lister's former girlfriend from a parallel universe; played by Chloë Annett"

"Holly, the supercomputer onboard Red Dwarf; played by Norman Lovett from Series I-II and VII onward and Hattie Hayridge from Series III-V"

"Kryten, a mechanoid originally from the Nova 5 whom Lister rebuilt; played by David Ross in the Series II episode, Kryten, and by Robert Llewellyn beginning from the Series III episode Backwards onward"

"The Cat, the last known member of a race of humanoids evolved from Lister's cat; played by Danny John-Jules"

"Arnold Rimmer, a hologram of Lister's former superior; played by Chris Barrie"

"Dave Lister, the only human survivor, who was suspended in stasis for 3 million years; played by Craig Charles"

"Hattie Hayridge - Holly (Series III - V)"

"Norman Lovett - Holly (Series I - II, VII - VIII, XII - The Promised Land)"