"In summary, in the first 3 years of our research we have made important contributions to the field of organocatalysis. In this highly competitive and fast moving topical area of organic chemistry we have set important milestones by, for example, developing the first metal-free, highly enantioselective Brønsted catalyzed biomimetic transferhydrogenations, cascade reductions, Strecker reactions, azaenamine additions, direct Mannich reactions, pyridine reductions, as well as domino Mannich-Michael additions. The enantioselectivities observed for such transformations are impressive with most exceeding 90% enantiomeric excess. In addition to these novel chiral ion pair catalyzed transformations, we were the first to realize that chiral Brønsted acids can activate carbonyl groups which resulted in the development of the first organocatalytic electrocyclic reactions. This is not only the first example of such a method but more significantly, it opens the door for many further enantioselective carbonyl transformations."
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Organocatalysis
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