"What variables have so far prevented wild H5N1 and H7N9 waterfowl viruses from becoming efficiently and pandemically transmissible in human populations, as the 1918 virus did? Do all influenza viruses, including poultry-adapted viruses, have the potential to acquire host adaptive mutations that lead to pandemicity, or is such evolution prevented by structural or functional evolutionary constraints associated with adaptation to the previous host? Does influenza A virus poultry adaptation place the virus in a particular evolutionary dead end with respect to subsequent human adaptation? Or can poultry-adapted influenza A viruses acquire mutations like those of the known pandemic viruses? If not, can they adapt to humans through different mechanisms? Again, we have no answers to these important questions."
Quote Details
Added by wikiquote-import-bot
Unverified quote
0 likes
Original Language: English
Available Languages (1)
Sources
Imported from EN Wikiquote
https://en.wikiquote.org/wiki/Influenza
Revision History
No revisions have been submitted for this quote.
Categories
Influenza
41 quotes on TrueQuotesView all quotes by Influenza →
Related Quotes
"As we now know, wild birds are the natural reservoir for influenza A viruses. With extensive antigenic and genetic di…"
"Many international health agencies and research laboratories collaborate to track influenza virus evolution, evaluate…"
"We are no doubt more prepared in 2018 for an infectious disease threat than in 1918. But it is critical to remember t…"
"The survival data for TGEV and MHV suggest that enveloped viruses can remain infectious on surfaces long enough for p…"
"The small British Crown dependency of Tristan da Cunha is one of the most isolated points on the planet. Over 1700 mi…"
"Influenza pandemics are events that have occurred in the past and will undoubtedly occur in the future. There is unce…"
"Waterbirds, to an influenza researcher, are more than majestic swans and charming mallards. They are instead stealthy…"
"The use of licensed inactivated trivalent influenza vaccine is increasing, but even if all high risk persons currentl…"
"Planning and preparedness efforts are widespread and ongoing, on a scale likely not imagined in 1918. Pandemic plans …"
"Sambucus nigra L. products - Sambucol - are based on a standardized black elderberry extract. They are natural remedi…"