"As we now know, wild birds are the natural reservoir for influenza A viruses. With extensive antigenic and genetic diversity inherent among influenza virus surface proteins, a strain to which humans are immunologically naïve could jump the species barrier at any time. A(H5N1) viruses and, more recently, A(H7N9) viruses, are two such examples. However, swine are also recognized as a “mixing vessel” for influenza viruses, and over the past two decades, there has been an increase in human cases following exposure to infected pigs. There is clearly, and alarmingly, a vast diversity of zoonotic sources of influenza A viruses that could acquire a transmissible phenotype in humans and cause a pandemic."
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Belser, JA ; Tumpey, TM. “The 1918 flu, 100 years later”: Science. 2018 Jan. Vol. 359, Issue 6373, pp. 255
https://en.wikiquote.org/wiki/Influenza
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Influenza
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