"It must have been one evening after midnight when I suddenly remembered my conversation with Einstein and particularly his statement, "It is the theory which decides what we can observe." I was immediately convinced that the key to the gate that had been closed for so long must be sought right here. ...We had always said so glibly that the path of the electron in the cloud chamber could be observed. But perhaps what we really observed was something much less. Perhaps we merely saw a series of discrete and ill-defined spots through which the electron had passed. ...The right question should therefore be: Can quantum mechanics represent the fact that an electron finds itself approximately in a given place and that it moves approximately with a given velocity, and can we make these approximations so close that they do not cause experimental difficulties? A brief calculation after my return to the Institute showed that one could indeed represent such situations mathematically, and that the approximations are governed by what would later be called the uncertainty principle of quantum mechanics: the product of the uncertainties in the measured values of the position and momentum (i.e., the product of mass and velocity) cannot be smaller than Planck's constant. This formulation, I felt, established the much-needed bridge between the cloud chamber observations and the mathematics of quantum mechanics. True, it had still to be proved that any experiment whatsoever was bound to set up situations satisfying the uncertainty principle, but this struck me as plausible a priori, since the processes involved in the experiment or the observation had necessarily to satisfy the laws of quantum mechanics. On this presupposition, experiments are unlikely to produce situations that do not accord with quantum mechanics. "It is the theory which decides what we can observe." I resolved to prove this by calculations based on simple experiments during the next few days."
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Werner Heisenberg, Physics and Beyond (1971), 6. Fresh Fields (1926-1927)
https://en.wikiquote.org/wiki/Electron
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Electron
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