"The drug's dangerous," she said, "but it gives insight. When a Truthsayer's gifted by the drug, she can look many places in her memory β in her body's memory. We look down so many avenues of the past...but only feminine avenues." Her voice took on a note of sadness. "Yet, there's a place where no Truthsayer can see. We are repelled by it, terrorized. It is said a man will come one day and find in the gift of the drug his inward eye. He will look where we cannot β into both feminine and masculine pasts." "Your Kwisatz Haderach?" "Yes, the one who can be many places at once: the Kwisatz Haderach. Many men have tried the drug . . . so many, but none has succeeded." "They tried and failed, all of them?" "Oh, no." She shook her head. "They tried and died."
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Paul Atreides and Reverend Mother Gaius Helen Mohiam, on the subject of men undergoing the spice trance.
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Dune
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