"There has probably never been a period in the history of thought entirely resembling the present. Thinkers everywhere are conscious of two things, first, that the region of mystery has never before been so clearly defined, and secondly, that that region can be entered more easily than has hitherto been the case; it may, therefore, perhaps be induced to render up some of its secrets if investigators of all schools pursue their search with determination. The problems with which we are faced, as we study the known facts of life and existence, are susceptible of clearer definition than heretofore, and though we do not know the answers to our questions, though we have not as yet discovered the solutions to our problems, though no panacea lies ready to our hand whereby we can remedy the world's ills, yet the very fact that we can define them, that we can point in the direction in which mystery lies, and that the light of science, of religions, and of philosophy, has been shed upon vast tracts which were earlier considered lands of darkness, is a guarantee of success in the future. We know so much more than was the case five hundred years ago, save in a few circles of wise men and mystics; we have discovered so many laws of nature, even though as yet we cannot apply them; and the knowledge of "things as they are" (and I choose these words very deliberately) has made immense strides. Lecture II, The Evolution of Substance"