"Here we show that sexual fate is also surprisingly labile in the testis: loss of the DMRT1 transcription factor 3 in mouse Sertoli cells, even in adults, activates Foxl2 and reprograms Sertoli cells into granulosa cells. In this environment, theca cells form, oestrogen is produced and germ cells appear feminized."
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Original Language: English
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Clinton K. Matson, et al, in "DMRT1 prevents female reprogramming in the postnatal mammalian testis" in Nature 476.7358 (2011), p. 101-104
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