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April 10, 2026
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"To be sure, risks abound; but no one is proposing compassionate stewardship of ecosystems by philosophers. Humans are capable of choosing our own future pain-sensitivity too; but any species-wide genomic shift in human pain tolerance will depend on the willingness of prospective parents to use preimplantation genetic screening."
"[H]uman nature as encoded in our DNA isn't immutable. Mankind's barbaric track-record to date is an unreliable guide to the future. If Homo sapiens' nastier alleles and their more sinister combinations can be silenced or edited out of the genome, and new improved code-sequences inserted instead, then the pessimists will be confounded. A major discontinuity in the development of life lies ahead. Providentially, we've learned that the DNA-driven world isn't written in God-given proprietary code it would be hubris to tamper with, but in bug-ridden open source amenable to improvement."
"... our descendants may recognize that we are the sociopathic emotional primitives in the grip of an affective psychosis. Jealousy, envy, resentment, ridicule, hate, anger, disgust, spite, contempt, schadenfreude and a whole gamut of nameless but mean-spirited states we undergo each day are a toxic legacy of our Darwinian past. More commonly, perhaps, our genetic make-up ensures we simply feel indifference to the plight of all but a handful of significant others in our lives. Right now, for instance, one knows dimly at some level that there is frightful and preventable suffering in the world. Yet most of us feel no overpowering moral urgency to do anything about it."
"[T]he existence of the mind-independent environment beyond one's world-simulation is a theoretical inference, not an empirical observation."
"Why expect a false theory of the world, i.e. classical physics, to yield a true account of consciousness?"
"Genes and culture have co-evolved. But crudely, natural selection "designed" male human primates to hunt nonhumans and build coalitions of other male human primates in order to wage territorial wars of aggression. Nature didn't design us to become a scientific community and collaborate to overcome aging. It's difficult to imagine that any human enemy could inflict such gruesome damage on the victims as growing old. The ravages of aging strike down combatants and civilians alike. So the trillions of dollars that humans currently spend on ways to harm and kill each other ("defence") would be more fruitfully spent on defeating our common enemy. We should work together to build a "Triple S" civilisation of superlongevity, superhappiness and superintelligence."
"If we don't address the genetic causes of suffering (physical and mental) we will find ourselves in 500 years enjoying material abundance via nanotech, living in a perfect democracy, colonizing space, and still sitting around wondering "Why are we miserable so much of the time? Why can't we all just get along? Why are we not all happy?""
"Today, status quo bias runs deep. Conservation biology is an ideology masquerading as a science. Many researchers seek to extend the tenets of conservation biology to humans. By contrast, a benevolent superintelligence might view Darwinian life on Earth as an infestation of biological malware and act accordingly. The amount of suffering caused by Homo sapiens is hard to quantify. But the suffering is immense and growing daily with the spread of industrialised animal abuse."
"Humans are prone to status quo bias. So let's do a thought-experiment. Imagine we stumble across an advanced civilisation that has abolished predation, disease, famine, and all the horrors of primitive Darwinian life. The descendants of archaic lifeforms flourish unmolested in their wildlife parks â free living, but not "wild". Should we urge scrapping their regime of compassionate stewardship of the living world â and a return to asphyxiation, disembowelling and being eaten alive? Or is a happy biosphere best conserved intact?"
"I think there's an asymmetry. There's this fable of Ursula Le Guin, short story, Ones Who Walk Away From Omelas. We're invited to imagine this city of delights, vast city of incredible wonderful pleasures but the existence of Omelas, this city of delights depends on the torment and abuse of a single child. The question is would you walk away from Omelas and what does walking away from Omelas entail. Now, personally I am someone who would walk away from Omelas. The world does not have an off switch, an off button and I think if one is whether a Buddhist of a negative utilitarian, or someone who believes in suffering-focused ethics, rather than to consider these theoretical apocalyptic scenarios it is more fruitful to work with secular and religious life lovers to phase out the biology of suffering in favor of gradients of intelligent wellbeing because one of the advantages of hedonic recalibration, i.e. ratcheting up hedonic set points is that it doesn't ask people to give up their existing values and preferences with complications."
"All that matters is the pleasure-pain axis. Pain and pleasure disclose the world's inbuilt metric of (dis)value. Our overriding ethical obligation is to minimise suffering. After we have reprogrammed the biosphere to wipe out experience below "hedonic zero", we should build a "triple S" civilisation based on gradients of superhuman bliss. The nature of ultimate reality baffles me. But intelligent moral agents will need to understand the multiverse if we are to grasp the nature and scope of our wider cosmological responsibilities. My working assumption is non-materialist physicalism. Formally, the world is completely described by the equation(s) of physics, presumably a relativistic analogue of the universal SchrĂśdinger equation. Tentatively, I'm a wavefunction monist who believes we are patterns of qualia in a high-dimensional complex Hilbert space. Experience discloses the intrinsic nature of the physical: the "fire" in the equations. The solutions to the equations of QFT or its generalisation yield the values of qualia. What makes biological minds distinctive, in my view, isn't subjective experience per se, but rather non-psychotic binding. Phenomenal binding is what consciousness is evolutionarily "for". Without the superposition principle of QM, our minds wouldn't be able to simulate fitness-relevant patterns in the local environment. When awake, we are quantum minds running subjectively classical world-simulations. I am an inferential realist about perception. Metaphysically, I explore a zero ontology [...] the total information content of reality must be zero on pain of a miraculous creation of information ex nihilo. Epistemologically, I incline to a radical scepticism that would be sterile to articulate. Alas, the history of philosophy twinned with the principle of mediocrity suggests I burble as much nonsense as everyone else."
"In future, nerve cell responsiveness to naturally occurring endogenous opioids can be increased via receptor enrichment in the brain too. In principle, we can modulate their lifelong "overexpression", intermittently heightened (or gently diminished) by whatever kinds of personal and environmental contingencies we judge fit. Both functionally and anatomically, our reward pathways can be made "bigger and better". But intelligent emotional self-mastery will involve re-engineering the mind-brain so we derive the most intense rewards from activities we deem most lastingly worthwhile: i.e. prioritising our higher-order desires over legacy first-order appetites. Natural selection has "encephalised" our emotions to benefit our genes. Rational agents can "re-encephalise" our emotions to benefit us."
"[T]rue hedonic engineering, as distinct from mindless hedonism or reckless personal experimentation, can be profoundly good for our character. Character-building technologies can benefit utilitarians and non-utilitarians alike. Potentially, we can use a convergence of biotech, nanorobotics and information technology to gain control over our emotions and become better (post-)human beings, to cultivate the virtues, strength of character, decency, to become kinder, friendlier, more compassionate: to become the type of (post)human beings that we might aspire to be, but aren't, and biologically couldn't be, with the neural machinery of unenriched minds. Given our Darwinian biology, too many forms of admirable behaviour simply aren't rewarding enough for us to practise them consistently: our second-order desires to live better lives as better people are often feeble echoes of our baser passions."
"[A]s well as seriously â indeed exhaustively â researching everything that could conceivably go wrong, I think we should also investigate what could go right. The world is racked by suffering. The hedonic treadmill might more aptly be called a dolorous treadmill. Hundreds of millions of people are currently depressed, pain-ridden or both. Hundreds of billions of non-human animals are suffering too. If we weren't so inured to a world of pain and misery, then the biosphere would be reckoned in the throes of a global medical emergency. Thanks to breakthroughs in biotechnology, pain-thresholds, default anxiety levels, hedonic range and hedonic set-points are all now adjustable parameters in human and non-human animals alike. We are living in the final century of life on Earth in which suffering is biologically inevitable. As a society, we need an ethical debate about how much pain and misery we want to preserve and create."
"All moral tradeoffs are messy. However, on some fairly modest ethical assumptions, when a severe and irreconcilable conflict of interests occurs, then the interests of the more sentient take precedence over the less sentient. This rule of thumb holds regardless of the age, race or species of the victim."
"...it won't just be the quality and quantity of consciousness in the world that will be transformed in the post-Darwinian Transition. As (post-)humanity emerges from the neurochemical Dark Ages, enriched dopaminergic function in particular may sharpen the sheer intensity and meaningfulness of every moment of conscious existence. For a generation whose lifetimes span both modes of awareness, it will be as if they had just woken up. They will feel they had hitherto been sleep-walking through life in a twilit stupor. Thereafter their former mundane and minimal existence may be recalled only as some kind of zombified trance-state whose nature they were physiologically incapable of recognising..."
"The Hedonistic Imperative outlines how genetic engineering and nanotechnology will abolish suffering in all sentient life. This project is ambitious but technically feasible. It is also instrumentally rational and ethically mandatory. The metabolic pathways of pain and malaise evolved only because they once served the fitness of our genes. They will be replaced by a different sort of neural architecture. States of sublime well-being are destined to become the genetically pre-programmed norm of mental health. The world's last aversive experience will be a precisely dateable event. Two hundred years ago, powerful synthetic pain-killers and surgical anesthetics were unknown. The notion that physical pain could be banished from most people's lives would have seemed absurd. Today most of us in the technically advanced nations take its routine absence for granted. The prospect that what we describe as psychological pain, too, could ever be banished is equally counter-intuitive. The feasibility of its abolition turns its deliberate retention into an issue of social policy and ethical choice."
"Much more seriously, in those traditional eco-systems that we chose to retain, millions of non-human animals will continue periodically to starve, die horribly of thirst and disease, or even get eaten alive. This is commonly viewed as "natural" and hence basically OK. It would indeed be comforting to think that in some sense this ongoing animal holocaust doesn't matter too much. We often find it convenient to act as though the capacity to suffer were somehow inseparably bound up with linguistic ability or ratiocinative prowess. Yet there is absolutely no evidence that this is the case, and a great deal that it isn't."
"The functional regions of the brain which subserve physical agony, the "pain centres", and the mainly limbic substrates of emotion, appear in phylogenetic terms to be remarkably constant in the vertebrate line. The neural pathways involving serotonin, the periaquaductal grey matter, bradykinin, dynorphin, ATP receptors, the major opioid families, substance P etc all existed long before hominids walked the earth. Not merely is the biochemistry of suffering disturbingly similar where not effectively type-identical across a wide spectrum of vertebrate (and even some invertebrate) species. It is at least possible that members of any species whose members have more pain cells exhibiting greater synaptic density than humans sometimes suffer more atrociously than we do, whatever their notional "intelligence"."
"No amount of happiness enjoyed by some organisms can notionally justify the indescribable horrors of Auschwitz. [...] Nor can the fun and games outweigh the sporadic frightfulness of pain and despair that occurs every second of every day. For there's nothing inherently wrong with non-sentience or [...] non-existence; whereas there is something frightfully and self-intimatingly wrong with suffering."
"Negative-utilitarianism is only one particular denomination of a broad church to which the reader may well in any case not subscribe. Fortunately, the program can be defended on grounds that utilitarians of all stripes can agree on. So a defence will be mounted against critics of the theory and application of a utilitarian ethic in general. For in practice the most potent and effective means of curing unpleasantness is to ensure that a defining aspect of future states of mind is their permeation with the molecular chemistry of ecstasy: both genetically precoded and pharmacologically fine-tuned. Orthodox utilitarians will doubtless find the cornucopian abundance of bliss this strategy delivers is itself an extra source of moral value. Future generations of native ecstatics are unlikely to disagree."
"It's easy to convince oneself that things can't really be that terrible, that the horror I allude to is being overblown, that what is going on elsewhere in space-time is somehow less real than the here-and-now, or that the good in the world somehow offsets the bad. Yet however vividly one thinks one can imagine what agony, torture or suicidal despair must be like, the reality is inconceivably worse. The force of "inconceivably" is itself largely inconceivable here. Blurry images of Orwell's "Room 101" can barely even hint at what I'm talking about. Even if one's ancestral namesakes [aka "younger self"] underwent great pain, then the state-dependence of memories means that much of pain's sheer dreadfulness is semantically, cognitively and emotionally inaccessible in the here-and-now. So this manifesto's rhapsodies on the incredible joys that do indeed lie ahead tend to belie its underlying seriousness of purpose. For the biological strategy is propounded here in deadly moral earnest."
"One should be wary of assuming that we're the folk who can properly look after ourselves, whereas our descendants, if they become genetically pre-programmed ecstatics, will get trapped in robot-serviced states of infantile dependence. For it shouldn't be forgotten that exuberantly happy people also have a fierce will to survive. They love life dearly. They take on daunting challenges against seemingly impossible odds. One of the hallmarks of many endogenous depressive states, on the other hand, is so-called behavioural despair. If one learns that apparently no amount of effort can rescue one from an aversive stimulus, then one tends to sink into a lethargic stupor. This syndrome of "learned helplessness" may persist even when the opportunity to escape from the nasty stimulus subsequently arises."
"Taking the abolitionist project to the rest of the galaxy and beyond sounds crazy today; but it's the application of technology to a very homely moral precept writ large, not the outgrowth of a revolutionary new ethical theory. So long as sentient beings suffer extraordinary unpleasantness - whether on Earth or perhaps elsewhere - there is a presumptive case to eradicate such suffering wherever it is found."
"Any plea ... for institutionalized risk-assessment, beefed-up bioethics panels, academic review bodies, worse-case scenario planning, more intensive computer simulations, systematic long-term planning and the institutionalized study of existential risks is admirable. But so is urgent action to combat the global pandemic of suffering. "The easiest pain to bear is someone else's"."
"One cannot really believe that an emotion exists outside one's own consciousness without participating in that emotion and making it to some extent one's own. ⌠Similarly, I can't in any serious sense believe that something I am doing is hurting you without my image of that hurt acting on me as the hurt itself would do if I myself experienced it, encouraging me to desist."
"What exactly is the minority moral position for which members of a gathering such as this are likely to be propagandists? It will certainly differ slightly from person to person. There is, however, one rather minimal principle to which I trust that all here would assent, namely that the suffering or frustration of an animal of another species is an evil of the same general sort as is the suffering or frustration of a human being, and that we humans have the same general sort of moral obligation to refrain from causing, and to try actively to prevent, such evil when it concerns animals as when it concerns human beings."
"The restraints we are seeking to impose are ones which can only be opposed by a failure in empathy towards non-human animals which constitutes an irrational blindness to the fact of the basic sameness of suffering in whatever species of animal it occurs; an irrationality incompatible with clear thought about the issue."
"If the view outlined here is correct, namely that people cannot really grasp the nature of the suffering which their behaviour creates without wishing to refrain from it, you may ask how do experimenters, factory farmers, cattle transporters, etc., carry on? The answer is, in one way or another, I believe, that they do not really grasp what they are doing. At some level it may be right to say âForgive them, for they know not what they doâ. But the immediate task is to make people realise sufficiently what they, or others on their behalf, are doing, so that it will be done no more."
"How far our position is a minority one will differ from person to person here. If we are against factory farms, we are morally condemning widespread and perfectly legal practices involving perhaps the majority of the human community. If we are vegetarians, we hold a position which is very much a minority one. If we are pretty radical anti-vivisectionists, we also hold what seems to be a minority position, involving as it does a radical criticism of the law and the establishment of this country."
"Despite his inability to build a system, Sidgwick had made Cambridge Benthamite in its social reasoning. Perhaps this development was always inevitable in a university which had aimed to turn out mathematical rather than classical curates. But it had important consequences. Only a philosophy based on a hedonistic calculus could provided exact reasoning about social policy. Alfred Marshall was a product of Sidgwick's Cambridge. On the other hand, Sidgwick left moral philosophy in a mess. Intuitionist ideas revived, with an admixture of Hegelianism, in the more dynamic form of Idealism. But its headquarters were at Oxford rather than Cambridge; its high priests the Oxford philosophers Bradley and T. H. Green. Cambridge had become too critical, too empirical, to accept its ethics in metaphysical form. The way was open for G. E. Moore to construct a Cambridge system detached from both Benthamism and metaphysics. Moore was as much a product of Sidgwick's failure as was Marshall."
"The method is Bentham's; but there is none of Bentham's strong critical antagonism to the institutions of his time, and the mode of thought is much more what we might expect from an end-of-the-nineteenth-century Blackstone, or from an English Hegel, showing the rationality of the existing order of things, with only a few modest proposals of reform. If this is Benthamism, it is Benthamism grown tame and sleek."
"J. J. C. Smart, a prominent 20th-century utilitarian, said simply that [Sidgwick's] The Methods is âthe best book ever written on ethicsâ. Derek Parfit agreed with that judgement, acknowledging that some books, like Platoâs Republic and Aristotleâs Ethics, are greater achievements, but noting that because Sidgwick could build on the work of his predecessors, The Methods âcontains the largest number of true and important claimsâ."
"We have next to consider who the âallâ are, whose happiness is to be taken into account. Are we to extend our concern to all the beings capable of pleasure and pain whose feelings are affected by our conduct? or are we to confine our view to human happiness? The former view is the one adopted by Bentham and Mill, and (I believe) by the Utilitarian school generally: and is obviously most in accordance with the universality that is characteristic of their principle. It is the Good Universal, interpreted and defined as âhappinessâ or âpleasure,â at which a Utilitarian considers it his duty to aim: and it seems arbitrary and unreasonable to exclude from the end, as so conceived, any pleasure of any sentient being."
"The good of any one individual is of no more importance, from the point of view...of the Universe, than the good of any other; unless, that is, there are special grounds for believing that more good is likely to be realized in the one case than in the other."
"[T]he inhuman severity of the paradox that âpleasure and pain are indifferent to the wise man,â never failed to have a repellent effect; and the imaginary rack on which an imaginary sage had to be maintained in perfect happiness, was at any rate a dangerous instrument of dialectical torment or the actual philosopher. Christianity extricated the moral consciousness from this dilemma between base subserviency and inhuman indifference to the feelings of the moral agent. It compromised the long conflict between Virtue and Pleasure, by transferring to another world the fullest realisation of both; thus enabling orthodox morality to assert itself, as reasonable and natural, without denying the concurrent reasonableness and naturalness of the individualâs desire for bliss without allow."
"The denial of any distinction between foreseen and intended consequences, as far as responsibility is concerned, was not made by Sidgwick in developing any one 'method of ethics'; he made this important move on behalf of everybody and just on its own account; and I think it plausible to suggest that this move on the part of Sidgwick explains the difference between old-fashioned Utilitarianism and the consequentialism, as I name it, which marks him and every English academic moral philosopher since him."
"The last comprehensive attempt to restate the principles of a free society, already much qualified and in the restrained form expected of an academic textbook, is Henry Sidgwick, The Elements of Politics (London: Macmillan, 1891). Though in many respects an admirable work, it scarcely represents what must be regarded as the British liberal tradition and is strongly tainted with that rationalist utilitarianism which led to socialism."
"Now, I agree with Mill in holding that the scientific study of the structures and functions of the different governments that have actually existed in human societies cannot well be pursued in complete separation from the scientific study of other important elements of the societies in question: whether the aim of the student is to ascertain the causes of the differences in such governments or to examine their effects. But I do not think that there is any fundamental difference, in this respect, between the study of political relations and the study of economic relations, or, again, of religion, of art, of science and philosophy, as factors of social life. In each of these eases the student concentrates his attention on one element of human history which can only be partially separated from other components of the whole complex fact of social development. Experience seems to show that this kind of concentration, and consequent partial separation of historical and sociological study into special branches, is unavoidable in the division of intellectual labour which the growth of our knowledge renders necessary in a continually increasing degree."
"[T]he history of thought [âŚ] reveal[s] discrepancy between the intuitions of one age and those of a subsequent generation. But where the conflicting beliefs are not contemporaneous, it is usually not clear that the earlier thinker would have maintained his conviction if confronted by the arguments of the later. The history of thought, however, I need hardly say, affords abundant instances of similar conflict among contemporaries; and as conversions are extremely rare in philosophical controversy, I suppose the conflict in most cases affects intuitionsâwhat is self-evident to one mind is not so to another. It is obvious that in any such conflict there must be error on one side or the other, or on both. The natural man will often decide unhesitatingly that the error is on the other side. But it is manifest that a philosophic mind cannot do this, unless it can prove independently that the conflicting intuitor has an inferior faculty of envisaging truth in general or this kind of truth; one who cannot do this must reasonably submit to a loss of confidence in any intuition of his own that thus is found to conflict with anotherâs."
"How far we are to consider the interests of posterity when they seem to conflict with those of now-existing human beings? The answer to this, though, seems clear: the time at which a man exists canât affect the value of his happiness from a universal point of view; so the interests of posterity must concern a utilitarian as much as those of his contemporariesâexcept in that the effect of his actions on the lives and even the existence of posterity must be more uncertain."
"Each person is morally obliged to regard the good of anyone else as much as his own good, except when he judges it to be less, when impartially viewed, or less certainly knowable or attainable by him."
"It is in their purely physical aspect, as complex processes of corporeal change, that [physical processes] are means to the maintenance of life: but so long as we confine our attention to their corporeal aspect,âregarding them merely as complex movements of certain particles of organised matterâit seems impossible to attribute to these movements, considered in themselves, either goodness or badness. I cannot conceive it to be an ultimate end of rational action to secure that these complex movements should be of one kind rather than another, or that they should be continued for a longer rather than a shorter period. In short, if a certain quality of human Life is that which is ultimately desirable, it must belong to human Life regarded on its psychical side, or, briefly, Consciousness."
"A universal refusal to propagate the human species would be the greatest of conceivable crimes from a Utilitarian point of view"
"it is reasonable for a Utilitarian to praise any conduct more felicific in its tendency than what an average man would do under the given circumstances:âbeing aware of course that the limit down to which praiseworthiness extends must be relative to the particular state of moral progress reached by mankind generally in his age and country; and that it is desirable to make continual efforts to elevate this standard."
"Platoâs reason for claiming that the life of the Philosopher has more pleasure than that of the Sensualist is palpably inadequate. The philosopher, he argues, has tried both kinds of pleasure, sensual as well as intellectual, and prefers the delights of philosophic life; the sensualist ought therefore to trust his decision and follow his example. But who can tell that the philosopherâs constitution is not such as to render the enjoyments of the senses, in his case, comparatively feeble?"
"it seems scarcely extravagant to say that, amid all the profuse waste of the means of happiness which men commit, there is no imprudence more flagrant than that of Selfishness in the ordinary sense of the term,âthat excessive concentration of attention on the individualâs own happiness which renders it impossible for him to feel any strong interest in the pleasures and pains of others."
"Is it total or average happiness that we seek to make a maximum?...we foresee as possible that an increase in [population] numbers will be accompanied by a decrease in average happiness...if we take Utilitarianism to prescribe, as the ultimate end of action, happiness on the whole...it would follow that, if the additional population enjoy on the whole positive happiness, we ought to weigh the amount of happiness gained by the extra number against the amount lost by the remainder. So that, strictly conceived, the point up to which, on Utilitarian principles, population ought to be encouraged to increase, is not that at which average happiness is the greatest possible...but that at which the product formed by multiplying the number of persons living into the amount of average happiness reaches its maximum."
"Many religious persons think that the highest reason for doing anything is that it is Godâs Will: while to others âSelf-realisationâ or âSelf-developmentâ, and to others, again, âLife according to natureâ appear the really ultimate ends. And it is not hard to understand why conceptions such as these are regarded as supplying deeper and more completely satisfying answers to the fundamental question of Ethics, than those before named: since they do not merely represent I what ought to be, as such; they represent it in an apparently simple relation to what actually is. God, Nature, Self, are the fundamental facts of existence; the knowledge of what will accomplish Godâs Will, what is, âaccording to Natureâ, what will realise the true Self in each of us, would seem to solve the deepest problems of Metaphysics as well as of Ethics. But [âŚ] [t]he introduction of these notions into Ethics is liable to bring with it a fundamental confusion between âwhat isâ and âwhat ought to beâ, destructive of all clearness in ethical reasoning: and if this confusion is avoided, the strictly ethical import of such notions, when made explicit, appears always to lead us to one or other of the methods previously distinguished."
"I may begin by laying down as a principle that âall pain of human or rational beings is to be avoidedâ; and then afterwards may be led to enunciate the wider rule that âall pain is to be avoidedâ; it being made evident to me that the difference of rationality between two species of sentient beings is no ground for establishing a fundamental ethical distinction between their respective pains."