First Quote Added
April 10, 2026
Latest Quote Added
"Whatever is known to us by consciousness, is known beyond possibility of question. What one sees or feels, whether bodily or mentally, one cannot but be sure that one sees or feels. No science is required for the purpose of establishing such truths; no rules of art can render our knowledge of them more certain than it is in itself. There is no logic for this portion of our knowledge."
"... the genetic code is in fact literally identical in all animals, plants and bacteria ... All earthly living things are certainly descended from a single ancestor."
"The river of my title is a river of DNA, and it flows through time, not space. It is a river of information, not a river of bones and tissues."
"The enjoyments of life (such was now my theory) are sufficient to make it a pleasant thing, when they are taken en passant, without being made a principal object. Once make them so, and they are immediately felt to be insufficient. They will not bear a scrutinizing examination. Ask yourself whether you are happy, and you cease to be so. The only chance is to treat, not happiness, but some end external to it, as the purpose of life. Let your self-consciousness, your scrutiny, your self-interrogation, exhaust themselves on that; and if otherwise fortunately circumstanced you will inhale happiness with the air you breathe, without dwelling on it or thinking about it, without either forestalling it in imagination, or putting it to flight by fatal questioning. This theory now became the basis of my philosophy of life. And I still hold to it as the best theory for all those who have but a moderate degree of sensibility and of capacity for enjoyment; that is, for the great majority of mankind."
"... you need more than luck to navigate successfully through a thousand sieves in succession."
"Each generation is a filter, a sieve; good genes tend to fall through the sieve into the next generation; bad genes tend to end up in bodies that die young or without reproducing."
"Those only are happy (I thought) who have their minds fixed on some object other than their own happiness; on the happiness of others, on the improvement of mankind, even on some art or pursuit, followed not as a means, but as itself an ideal end. Aiming thus at something else, they find happiness by the way."
"Aim at something great; aim at things which are difficult; and there is no great thing which is not difficult. Do not pare down your undertaking to what you can hope to see successful in the next few years, or in the years of your own life. Fear not the reproach of Quixotism and impracticability, or to be pointed at as the knight-errants of an idea. After you have well weighed what you undertake, if you see your way clearly, and are convinced that you are right, go forward, even though you...do it at the risk of being torn to pieces by the very men through whose changed hearts your purpose will one day be accomplished. Fight on with all your strength against whatever odds, and with however small a band of supporters. If you are right, the time will come when that small band will swell into a multitude: you will at least lay the foundations of something memorable, and you may...—though you ought not to need or expect so great a reward—be spared to see that work completed which, when you began it, you only hoped it might be given to you to help forward a few stages on its way."
"The world becomes full of organisms that have what it takes to become ancestors. That, in a sentence, is Darwinism."
"Mitochondrial DNA is blessedly celibate. (p.53)"
"The experiences of this period had two very marked effects on my opinions and character. In the first place, they led me to adopt a theory of life, very unlike that on which I had before acted, and having much in common with what at that time I certainly had never heard of, the anti-self-consciousness theory of Carlyle."
"The total amount of suffering per year in the natural world is beyond all decent contemplation. During the minute it takes me to compose this sentence, thousands of animals are being eaten alive; others are running for their lives, whimpering with fear; others are being slowly devoured from within by rasping parasites; thousands of all kinds are dying of starvation, thirst and disease. [...] In a universe of blind physical forces and genetic replication, some people are going to get hurt, other people are going to get lucky, and you won't find any rhyme or reason in it, nor any justice. The universe we observe has precisely the properties we should expect if there is, at bottom, no design, no purpose, no evil and no good, nothing but blind, pitiless indifference. DNA neither knows nor cares. DNA just is. And we dance to its music."
"In one way or another, all my books have been devoted to expounding and exploring the almost limitless power of the Darwinian principle—power unleashed whenever and wherever there is enough time for the consequences of primordial self-replication to unfold."
"When, however, not more than half that duration of time had elapsed, a small ray of light broke in upon my gloom. I was reading, accidentally, Marmontel's "Mémoires," and came to the passage which relates his father's death, the distressed position of the family, and the sudden inspiration by which he, then a mere boy, felt and made them feel that he would be everything to them—would supply the place of all that they had lost. A vivid conception of the scene and its feelings came over me, and I was moved to tears. From this moment my been grew lighter. The oppression of the thought that all feeling was dead within me, was gone. I was no longer hopeless: I was not a stock or a stone. I had still, it seemed, some of the material out of which all worth of character, and all capacity for happiness, are made. ...Thus the cloud gradually drew off, and I again enjoyed life: and though I had several relapses, some of which lasted many months, I never again was as miserable as I had been."
"Everybody knows that the same sum of money is of much greater value to a poor man that to a rich one. Give £10 a year to the man who has but £10 a year, you double his income, and you nearly double his enjoyments. Add £10 more, you do not add to his enjoyments so much as you did by the first £10. The third £10 is less valuable than the second, and the fourth less valuable than the third. To the possessor of £1,000 a year the addition of £10 would be scarcely perceptible; to the possessor of £10,000 it would not be worth slooping for. The richer a man is the less he is benefited by any further addition to his income. The man of £4,000 a year has four times the income of the man who has but £1,000; but does anybody suppose that he has four times the happiness?"
"[W]hen the ricochets of atomic billiards chance to put together an object that has a certain, seemingly innocent property, something momentous happens in the universe. That property is an ability to self-replicate; that is, the object is able to use the surrounding materials to make exact copies of itself, including replicas of such minor flaws in copying as may occasionally arise. What will follow from this singular occurrence, anywhere in the universe, is Darwinian selection and hence the baroque extravaganza that, on this planet, we call life. Never were so many facts explained by so few assumptions. Not only does the Darwinian theory command superabundant power to explain. Its economy in doing so has a sinewy elegance, a poetic beauty that outclasses even the most haunting of the world's origin myths."
"If you have a faith, it is statistically overwhelmingly likely that it is the same faith as your parents and grandparents had. No doubt soaring cathedrals, stirring music, moving stories and parables, help a bit. But by far the most important variable determining your religion is the accident of birth. The convictions that you so passionately believe would have been a completely different, and largely contradictory, set of convictions, if only you had happened to be born in a different place. Epidemiology, not evidence."
"I frequently asked myself, if I could, or if I was bound to go on living, when life must be passed in this manner. I generally answered to myself, that I did not think I could possibly bear it beyond a year."
"The patient typically finds himself impelled by some deep, inner conviction that something is true, or right, or virtuous: a conviction that doesn't seem to owe anything to evidence or reason, but which, nevertheless, he feels as totally compelling and convincing. We doctors refer to such a belief as "faith"."
"Like computer viruses, successful mind viruses will tend to be hard for their victims to detect. If you are the victim of one, the chances are that you won't know it, and may even vigorously deny it. Accepting that a virus might be difficult to detect in your own mind, what tell-tale signs might you look out for? I shall answer by imaging how a medical textbook might describe the typical symptoms of a sufferer (arbitrarily assumed to be male)."
"I had obtained some distinction, and felt myself of some importance, before the desire of distinction and of importance had grown into a passion: and little as it was which I had attained, yet having been attained too early, like all pleasures enjoyed too soon, it had made me blasé and indifferent to the pursuit. Thus neither selfish nor unselfish pleasures were pleasures to me. And there seemed no power in nature sufficient to begin the formation of my character anew, and create in a mind now irretrievably analytic, fresh associations of pleasure with any of the objects of human desire."
"No longer enslaved or made dependent by force of law, the great majority are so by force of poverty; they are still chained to a place, to an occupation, and to conformity with the will of an employer, and debarred, by the accident of birth both from the enjoyments, and from the mental and moral advantages, which others inherit without exertion and independently of desert. That this is an evil equal to almost any of those against which mankind have hitherto struggled, the poor are not wrong in believing."
"Ten years ago, you could have traveled thousands of miles through the United States and never seen a baseball cap turned back to front. Today, the reverse baseball cap is ubiquitous. I do not know what the pattern of geographical spread of the reverse baseball cap precisely was, but epidemiology is certainly among the professions primarily qualified to study it."
"The second requirement of a virus-friendly environment – that it should obey a program of coded instructions – is again only quantitatively less true for brains than for cells or computers. We sometimes obey orders from one another, but also we sometimes don't. Nevertheless, it is a telling fact that, the world over, the vast majority of children follow the religion of their parents rather than any of the other available religions. Instructions to genuflect, to bow towards Mecca, to nod one's head rhythmically towards the wall, to shake like a maniac, to "speak in tongues" – the list of such arbitrary and pointless motor patterns offered by religion alone is extensive – are obeyed, if not slavishly, at least with some reasonably high statistical probability."
"All those to whom I looked up, were of opinion that the pleasure of sympathy with human beings, and the feelings which made the good of others, and especially of mankind on a large scale, the object of existence, were the greatest and surest sources of happiness. Of the truth of this I was convinced, but to know that a feeling would make me happy if I had it, did not give me the feeling."
"Think about the two qualities that a virus, or any sort of parasitic replicator, demands of a friendly medium, the two qualities that make cellular machinery so friendly towards parasitic DNA, and that make computers so friendly towards computer viruses. These qualities are, firstly, a readiness to replicate information accurately, perhaps with some mistakes that are subsequently reproduced accurately; and, secondly, a readiness to obey instructions encoded in the information so replicated."
"With so many mind-bytes to be downloaded, so many mental codons to be replicated, it is no wonder that child brains are gullible, open to almost any suggestion, vulnerable to subversion, easy prey to Moonies, Scientologists and nuns. Like immune-deficient patients, children are wide open to mental infections that adults might brush off without effort."
"For I now saw, or thought I saw, what I had always before received with incredulity—that the habit of analysis has a tendency to wear away the feelings: as indeed it has, when no other mental habit is cultivated, and the analysing spirit remains without its natural complements and correctives."
"France has done more for even English history than England has."
"I have just discovered that without her father's consent this sweet, trusting, gullible six-year-old is being sent, for weekly instruction, to a Roman Catholic nun. What chance has she?"
"Scientific and technological progress themselves are value-neutral. They are just very good at doing what they do. If you want to do selfish, greedy, intolerant and violent things, scientific technology will provide you with by far the most efficient way of doing so. But if you want to do good, to solve the world's problems, to progress in the best value-laden sense, once again, there is no better means to those ends than the scientific way."
"I had always heard it maintained by my father, and was myself convinced, that the object of education should be to form the strongest possible associations of the salutary class; associations of pleasure with all things beneficial to the great whole, and of pain with all things hurtful to it."
"The late , a psychologist and author, calculated that if the motor car had evolved as fast as the computer, and over the same time period, "Today you would be able to buy a for £35, it would do three million miles to the gallon, and it would deliver enough power to drive the QE2 And if you were interested in miniaturisation, you could place half a dozen of them on a pinhead.""
"The likelihood is that, in 100,000 years time, we shall either have reverted to wild barbarism, or else civilisation will have advanced beyond all recognition – into colonies in outer space, for instance. In either case, evolutionary extrapolations from present conditions are likely to be highly misleading."
"My education, which was wholly his work, had been conducted without any regard to the possibility of its ending in this result; and I saw no use in giving him the pain of thinking that his plans had failed, when the failure was probably irremediable, and, at all events, beyond the power of his remedies. Of other friends, I had at that time none to whom I had any hope of making my condition intelligible. It was however abundantly intelligible to myself; and the more I dwelt upon it, the more hopeless it appeared."
"It might be plausibly maintained, that in almost every one of the leading controversies, past or present, in social philosophy, both sides were in the right in what they affirmed, though wrong in what they denied."
"It is an article of passionate faith among "politically correct" biologists and anthropologists that brain size has no connection with intelligence; that intelligence has nothing to do with genes; and that genes are probably nasty fascist things anyway."
"It may be that brain hardware has co-evolved with the internal virtual worlds that it creates. This can be called hardware-software co-evolution."
"In vain I sought relief from my favourite books; those memorials of past nobleness and greatness from which I had always hitherto drawn strength and animation. I read them now without feeling, or with the accustomed feeling minus all its charm; and I became persuaded, that my love of mankind, and of excellence for its own sake, had worn itself out. I sought no comfort by speaking to others of what I felt. If I had loved any one sufficiently to make confiding my griefs a necessity, I should not have been in the condition."
"Another force driving progressive evolution is the so-called "arms-race." Prey animals evolve faster running speeds because predators do. Consequently predators have to evolve even faster running speeds, and so on, in an escalating spiral. Such arms races probably account for the spectacularly advanced engineering of eyes, ears, brains, bat "radar" and all the other high-tech weaponry that animals display."
"There is no general reason to expect evolution to be progressive – even in the weak, value-neutral sense. There will be times when increased size of some organ is favoured and other times when decreased size is favoured. Most of the time, average-sized individuals will be favoured in the population and both extremes will be penalised. During these times the population exhibits evolutionary stasis (i.e., no change) with respect to the factor being measured. If we had a complete fossil record and looked for trends in some particular dimension, such as leg length, we would expect to see periods of no change alternating with fitful continuations or reversals in direction – like a weathervane in changeable, gusty weather."
"In this frame of mind it occurred to me to put the question directly to myself: "Suppose that all your objects in life were realized; that all the changes in institutions and opinions which you are looking forward to, could be completely effected at this very instant: would this be a great joy and happiness to you?" And an irrepressible self-consciousness distinctly answered, "No!" At this my heart sank within me: the whole foundation on which my life was constructed fell down. All my happiness was to have been found in the continual pursuit of this end. The end had ceased to charm, and how could there ever again be any interest in the means? I seemed to have nothing left to live for."
"How can great minds be produced in a country where the test of a great mind is agreeing in the opinions of small minds?"
"If we want to postulate a deity capable of engineering all the organized complexity in the world, either instantaneously or by guiding evolution, that deity must have been vastly complex in the first place. The creationist, whether a naive Bible-thumper or an educated bishop, simply postulates an already existing being of prodigious intelligence and complexity. If we are going to allow ourselves the luxury of postulating organized complexity without offering an explanation, we might as well make a job of it and simply postulate the existence of life as we know it!"
"There is one particular property of living things, however, that I want to single out as explicable only by Darwinian selection. This property is the one that has been the recurring topic of this book: adaptive complexity."
"From the winter of 1821, when I first read Bentham, and especially from the commencement of the Westminster Review, I had what might truly be called an object in life; to be a reformer of the world. My conception of my own happiness was entirely identified with this object. The personal sympathies I wished for were those of fellow labourers in this enterprise. I endeavoured to pick up as many flowers as I could by the way; but as a serious and permanent personal satisfaction to rest upon, my whole reliance was placed on this..."
"This not only misses the point, it is the precise antithesis of the point."
"There are people in the world who desperately want not to have to believe in Darwinism."
"[T]he speaker with whom I was most struck, though I dissented from nearly every word he said, was Thirlwall, the historian, since Bishop of St. David's, then a Chancery barrister, unknown except by a high reputation for eloquence acquired at the before the era of Austin and Macaulay. His speech was in answer to one of mine. Before he had uttered ten sentences, I set him down as the best speaker I had ever heard, and I have never since heard any one whom I placed above him."
"What I stated was, that the Conservative party was, by the law of its constitution, necessarily the stupidest party. Now, I do not retract this assertion; but I did not mean that Conservatives are generally stupid; I meant, that stupid persons are generally Conservative. I believe that to be so obvious and undeniable a fact that I hardly think any hon. Gentleman will question it. Now, if any party, in addition to whatever share it may possess of the ability of the community, has nearly the whole of its stupidity, that party, I apprehend, must by the law of its constitution be the stupidest party. And I do not see why hon. Gentlemen should feel that position at all offensive to them; for it ensures their being always an extremely powerful party."