"I've been asked from time to time, "How does it happen that you have made so many discoveries? Are you smarter than other scientists?" And my answer has been that I am sure that I am not smarter than other scientists. I don't have any precise evaluation of my IQ, but to the extent that psychologists have said that my IQ is about 160, I recognize that there are one hundred thousand or more people in the United States that have IQs higher than that. So I have said that I think I think harder, think more than other people do, than other scientists. That is, for years, almost all of my thinking was about science and scientific problems that I was interested in."

"We must not have a Nuclear war. We must begin to solve international disputes by the application of man's power of reason in a way that is worthy of the dignity of man. We must solve them by arbitration, negotiation, and the development of international law, the making of international agreements that will do justice to all nations and to all peoples and will benefit all nations and to all people. Now is the time to start."

"Planck’s constant and the quantum theory that is built around it are of extreme importance for chemistry—we may well be justified in saying that quantum theory is of greater importance to chemistry than to physics ... there is no part of chemistry that does not depend, in its fundamental theory, upon quantum principles."

"I realized that more and more I was saying, "It seems to me that we have come to the time war ought to be given up. It no longer makes sense to kill 20 million or 40 million people because of a dispute between two nations who are running things, or decisions made by the people who really are running things. It no longer makes sense. Nobody wins. Nobody benefits from destructive war of this sort and there is all of this human suffering." And Einstein was saying the same thing of course. So that is when we decided — my wife and I — that first, I was pretty effective as a speaker. Second, I better start boning up, studying these other fields so that nobody could stand up and say, "Well, the authorities say such and such ""

"Everyone should know that the "war on cancer" is largely a fraud, and that the National Cancer Institute and American Cancer Society are derelict in their duties to the people who support them."

"A substance showing resonance between two or more valence-bond structures does not contain molecules with the configurations and properties usually associated with these structures."

"Science cannot be stopped. Man will gather knowledge no matter what the consequences – and we cannot predict what they will be. Science will go on — whether we are pessimistic, or are optimistic, as I am. I know that great, interesting, and valuable discoveries can be made and will be made… But I know also that still more interesting discoveries will be made that I have not the imagination to describe — and I am awaiting them, full of curiosity and enthusiasm."

"We may, I believe, anticipate that the chemist of the future who is interested in the structure of proteins, nucleic acids, polysaccharides, and other complex substances with high molecular weight will come to rely upon a new structural chemistry, involving precise geometrical relationships among the atoms in the molecules and the rigorous application of the new structural principles, and that great progress will be made, through this technique, in the attack, by chemical methods, on the problems of biology and medicine."

"...when I started doing chemistry, I did it the way I fished – for the excitement, the discovery, the adventure, for going after the most elusive catch imaginable in uncharted seas."

"Chemists usually write about their chemical careers in terms of the different areas and the discrete projects in those areas on which they have worked. Essentially all my chemical investigations, however, are in only one area, and I tend to view my research not with respect to projects, but with respect to where I’ve been driven by two passions which I acquired in graduate school: I am passionate about the Periodic Table (and selenium, titanium and osmium are absolutely thrilling), and I am passionate about catalysis. What the ocean was to the child, the Periodic Table is to the chemist; new catalytic reactivity is, of course, my personal coelacanth."

"The discipline, nonetheless, is exacting: everything that can be observed should be observed, even if it is only recalled as the bland background from which the intriguing bits pop out like Venus in the evening sky. The goal is always finding something new, hopefully unimagined and, better still, hitherto unimaginable."

"We have a word game in English called "Twenty questions." To play Twenty Questions, one player imagines some object, and the other players must guess what it is by asking questions that can be answered with a "yes" or a "no." I imagine every language has a similar game, and, for those of us who speak the language of science, the game is called The Scientific Method."