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April 10, 2026
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"The seeds of a few kinds of weeds can be carried long distances by natural means; for instance, dandelion seeds are wind-transported, cockleburs and stickseeds are carried by the hair of animals. However, the seeds of most weeds are spread by human agencies, most commonly in mixtures with agricultural seed."
"Legumes are vital because they provide fixed nitrogen for agricultural soils (the recent substitution of synthetic nitrogen fertilizers certainly being a temporary expedient), and because they furnish most of the protein for human food in high-population parts of the world. Man's dependence on grasses and legumes has been coeval."
"If chromosomes are broken by various means, the broken ends appear to be adhesive and tend to fuse with one another 2-by-2. This has been abundantly illustrated in the studies of chromosomal aberrations induced by X-ray treatment. It also occurs after mechanical rupture of ring-shaped chromosomes during somatic mitoses in maize and is assumed to occur during the normal process of crossing-over."
"When, through radiation or other causes, chromosomes are broken within a single nucleus, 2-by-2 fusions may occur between the broken ends. These fusions may lead to rearrangements of parts of the chromatin complement, giving rise to various chromosomal aberrations which are detected as reciprocal translocations, inversions, deficiencies, etc. Since, in the well-investigated cases, the breakages occurred within a single nucleus, the conditions that lead to fusions of broken ends could not easily be ascertained."
"An experiment conducted in the mid-nineteen forties prepared me to expect unusual responses of a genome to challenges for which the genome is unprepared to meet in an orderly, programmed manner. In most known instances of this kind, the types of response were not predictable in advance of initial observations of them. It was necessary to subject the genome repeatedly to the same challenge in order to observe and appreciate the nature of the changes it induces. Familiar examples of this are the production of mutation by X-rays and by some mutagenic agents. In contrast to such âshocksâ for which the genome is unprepared, are those a genome must face repeatedly, and for which it is prepared to respond in a programmed manner. Examples are the âheat shockâ responses in eukaryotic organisms, and the âSOSâ responses in bacteria. Each of these initiates a highly programmed sequence of events within the cell that serves to cushion the effects of the shock. Some sensing mechanism must be present in these instances to alert the cell to imminent danger, and to set in motion the orderly sequence of events that will mitigate this danger. The responses of genomes to unanticipated challenges are not so precisely programmed. Nevertheless, these are sensed, and the genome responds in a descernible but initially unforeseen manner."
"In 1950, Barbara McClintock published a Classic PNAS article, âThe origin and behavior of mutable loci in maize,â which summarized the evidence leading to her discovery of transposition. The article described a number of genome alterations revealed through her studies of the Dissociation locus, the first mobile genetic element she identified. McClintock described the suite of nuclear events, including transposon activation and various chromosome aberrations and rearrangements, that unfolded in the wake of genetic crosses that brought together two broken chromosomes 9. McClintock left future generations with the challenge of understanding how genomes respond to genetic and environmental stresses by mounting adaptive responses that frequently include genome restructuring."
"In the year of her election to the National Academy, she began the series of experiments that led her to transpositionâwork that many now see as the most important of her career. At the time, only she thought so. To most, her conclusions seemed too radical."
"When Barbara McClintock was awarded a Nobel Prize for her work on gene transposition in corn plants, the most striking thing about her was that she made her discoveries by listening to what the corn spoke to her, by respecting the life of the corn and "letting it McClintock says she learned "the stories" of the plants. She "heard them. She watched the daily green journeys of growth from carth toward sky and sun. She knew her plants in the way a healer or mystic would have known them, from the inside, the inner voices of corn and woman speaking to one another. As an Indian woman, I come from a long history of people who have listened to the language of this continent, people who have known that corn grows with the songs and prayers of the people, that it has a story to tell, that the world is alive...This intuitive and common language is what I seek for my writing, work in touch with the mystery and force of life, work that speaks a few of the many voices around us, and it is important to me that McClintock listened to the voices of corn. It is important to the continuance of life that she told the truth of her method and that it reminded us all of where our strength, our knowing, and our sustenance come from. It is also poetry, this science, and I note how often scientific theories lead to the world of poetry and vision, theories telling us how atoms that were stars have been transformed into our living, breathing bodies. And in these theories, or maybe they should be called stories, we begin to understand how we are each many people, including the stars we once were, and how we are in essence the earth and the universe, how what we do travels clear around the earth and returns. In a single moment of our living, there is our ancestral and personal history, our future, even our deaths planted in us and already growing toward their fulfillment. The corn plants are there, and like all the rest we are forever merging our borders with theirs in the world collective."
"As a plant explorer, Iltis led expeditions to Mexico, Guatemala, Peru and Ecuador. His expertise focused on the corn and caper families, but he collected broadly. For example, he discovered two of the 13 species in the tomato genus, including one that proved to have a trait sought in the canning industry."
"Current evidence suggests that teosinte was first tended for its green ears and sugary pith by hunter-gatherers as an occasional rainy-season food in small âgardenâ populations away from its homeland, and not for its abundant grain-containing, hard fruitcases, which easily mass-collected but useless as food, are as yet unknown from the archeological record. A rare grain-liberating teosinte mutation (probably expressed in only one âfounderâ plant, a mazoid âEveâ), which exposed the encased grain for easy harvest, was soon recognized as useful, collected and planted (or self-planted). Thus maize was started on its way to a unique horticultural domestication that is not comparable to that of the temperate Old World mass-selected agricultural grains."
"The classification of biodiversity is the job of taxonomists who, born as packrats and inspired by a compulsion to explore and collect the world's biological riches, will risk life and limb to solve the great puzzles of biogeography, ethnobotany, and evolution."
"The general biological ignorance bodes ill for democratic decisions on environmental issues."
"All that we can say, looking at the avocado pit, is that whatever swallowed it must have been big. As big as those fossil skeletons staring out at us from behind the dusty glass of museum cases."
"When it comes to getting away, big pits are a handicap. A quarter-pound seed isn't going to be blown about by anything less than a hurricane, and in water an avocado pit sinks."
"Doing your own gardening makes you much more aware of food cycles, what it takes to grow it, and what the range of food quality is."
"The mere crossing of species, unaccompanied by selection, wise supervision, intelligent care, and the utmost patience, is not likely to result in marked good, and may result in vast harm. Unorganized effort is often most vicious in its tendencies."
"During the course of many years of investigation into the plant life of the world, creating new forms, modifying old ones, adapting others to new conditions, and blending still others, I have constantly been impressed with the similarity between the organization and development of plant and human life."
"What takes place within the structure of the leaf, then, with the aid of the wonderful green workmen, is this: A certain number of molecules of water, brought to the leaf from root and stem, are taken in hand and compounded with a certain number of molecules of carbon extracted from the air that has been brought into the leaf laboratory through its mouths or ta from the outside atmosphere. When the compound has been effected, we still have the atoms of hydrogen and oxygen that composed the water molecules and the atoms of carbon, but they are so marvelously put together that they no longer constitute the liquid water or the gas in which the carbon was imported. They now constitute an altogether new substance which is termed sugar. Thus only three elements are dealt with and these very familiar ones. It would seem as if almost any chemist should be able to manage a simple combination like that. But... no human chemist knows how to manage it. There are forces to be invoked in effecting that combination of which no chemist has any knowledge. Only the chlorophyll grains in the plant leaf have learned the secret, and up to the present they have kept their secret well."
"No one at all understands why it is possible for the plant cell that bears within its substance one of these green bodies to combine certain inorganic elements into nutritious foods, a feat that no human chemist can perform."
"When the wise plant developer goes into his garden or orchard... his eyes turn always first and foremost to the leaves..."
"The plant laboratories in which this wonderful and vitally essential transformation is effected are chiefly located in the leaf of the plant... the thoughtful person must regard this structureâthe most ordinary green leaf of tree or shrub or vine or the tiniest blade of grassâas in some respects the most wonderful thing in the world."
"The most interesting thing in the world, from the standpoint of animal economyâwhich of course includes human economyâis the wonderful laboratory or factory of the plant..."
"In manufacturing food for its own cells, the plant is producing a supply of food that will be available for the sustenance of animal cells also. Thus the entire animal World may be said to be a vast parasitic colony as absolutely dependent upon the vegetable colony for its essential food supplies as any other parasite is dependent upon its host."
"The plant, unlike the animal, has provided a special mechanismâa unique laboratoryâthrough which it is able to manufacture from the crude salts in watery solution, with the aid of another element taken from the air, a new compound which will serve the protoplasmic cell with food. That is to say, the plant organism as a whole comprises a laboratory for compounding the crude elements, which by themselves cannot be used as nourishment, into a substance that can be used as nourishment. ...The plant is the only place in the world where foodstuffs are manufactured, and that no animal of any kind could live without nourishment that was originally manufactured by some plant, the vital importance of the matter will be manifest."
"Big men are usually of simple, direct sincerity of character. These marks are found in Burbank, sweet, straightforward, unspoiled as a child, devoted to truth, never turning aside to seek fame or money or other personal reward. If his place be outside the great temple of science, not many of the rest of us will be found fit to enter."
"With broader opportunities, Burbank could have done a greater variety of things and touched life at more points; but he would thus have lost something of his simple intensity and fine delicacyâthings the schools do not give and too much contact with society sometimes takes away."
"In his way he belongs to the class of Faraday and the self-taught men of the last generation who dealt steadily with facts, while universities spent their energies on fine points of grammar, and a philosophy which, like an epiphytic plant, had its roots in the air."
"Burbank worked for years alone, not understood nor appreciated, and usually at a financial loss, for his instincts and aims were those of a scientist, not of a horticulturist."
"Burbank's special field is that of ; here he is artist as well as scientist. Academic, noâbut science is not necessarily bred in the academy. ...he has not studied in the universities, though his large library contains most of the books which relate to these subjects."
"Burbank is proud to acknowledge that his success rests on the science of Darwin..."
"For the sake of one great advance, he can afford to burn thousands of plants of which the combinations of inheritable character show little or no improvement over the parent stock."
"After a short experience in an agricultural implement manufactory he began market gardening and seed growing in a small way, one of his first and therefore now best known achievements being the development of the Burbank potato from a selected seedling of the Early Rose. On October 1, 1875, he removed from Massachusetts to Santa Rosa, California, where he has lived ever since devoting himself to the production of new forms of plants by crossing and selection."
"A unique, great genius!. To see him was the prime reason of my coming to America. He works to definite ends. He ought to be not only cherished but helped. Unaided he cannot do his best. He should be as well known and as widely appreciated in California as among scientific men in Europe."
"His principles are in full harmony with the teachings of science. His methods are hybridization and selection in the broadest sense and on the largest scale. One very illustrative example of his methods must suffice to convey an idea of the work necessary to produce a new race of superlative excellency. Forty thousand blackberry and raspberry hybrids were produced and grown until the fruit matured. Then from the whole lot a single variety was chosen as the best. It is now known under the name of "Paradox." All others were uprooted with their crop of ripening berries, heaped up into a pile twelve feet wide, fourteen feet high and twenty-two feet long, and burned. Nothing remained of that expensive and lengthy experiment, except the one parent plant of the new variety. Similar selections and similar amount of work have produced the famous plums, the brambles and the blackberries, the Shasta daisy, the peach-almond, the improved blueberries, the hybrid lilies, and the many other valuable fruits and garden-flowers that have made the fame of Burbank and the glory of horticultural California."
"The final and most important factor of Burbank's success is the inherent personal genius of the man, his innate sympathy with nature, aided by the practical education in plant biology derived from thirty years of constant study and experiment which enable him to perceive correlations and outcomes of plant growth which seem to have been visible to no other man."
"Burbank... wished to improve humans exactly as he made better plants... [he] outlined a four-step process... [but] actually accomplished all his feats with only two of his four steps... Ironically, he rooted the humanistic and "liberal" heart of his eugenics program in the two illusory processes... Burbank... advocated Lamarckian inheritance... Nature, in the wild or in horticulture, works on Darwinian, not Lamarckian, principles. Acquired characters are not inherited, and desired improvement occurs by rigorous selection with elimination of the vast majority from the reproductive stream. Burbank could develop new breeds, but he could not alter the rules. He actually worked by extensive hybridization and uncompromising selection, though his own success fooled him into thinking that nature helped his efforts by Lamarckian inheritance. The Lamarckian theme sets the keystone for Burbank's liberal eugenics, based upon the genetic effects of good nurturing. The fallacy of Lamarckianism marks the utter failure of his arguement."
"He introduced almost every "new" trait by directed immigrationâthat is, by importing favorable features from other lineages through hybridization."
"As a young man he developed the Burbank potato in his native Massachusetts and used the proceeds to bankroll his larger, lifetime operation in California."
"Every child should have mud pies, grasshoppers, water-bugs, tadpoles, frogs, mud-turtles, elderberries, wild strawberries, acorns, chestnuts, trees to climb, brooks to wade in, water-lilies, woodchucks, bats, bees, butterflies, various animals to pet, hay-fields, pine-cones, rocks to roll, sand, snakes, huckleberries and hornets and any child who has been deprived of these has been deprived of the best part of his education. By being well acquainted with all these they come into most intimate harmony with nature, whose lessons are, of course, natural and wholesome."
"We may compare this sum of the life forces, which we call heredity, to the character of a sensitive plate in the camera. Outside pictures impress themselves more or less distinctly on the sensitive plate... Stored within heredity are all joys, sorrows, loves, hates, music, art, temples, palaces, pyramids, hovels, kings, queens, paupers, bards, prophets and philosophers, oceans, caves, volcanoes, floods, earthquakes, wars, triumphs, defeats, reverence, courage, wisdom, virtue, love and beauty, time, space, and all the mysteries of the universe. The appropriate environments will bring out and intensify all these general human hereditary experiences and quicken them again into life and action, thus modifying for good or evil, characterâheredityâdestiny."
"Heredity is not the dark specter which some people have thoughtâmerciless and unchangeable, the embodiment of Fate itself. This dark, pessimistic belief which tinges even the literature of to-day comes, no doubt, from the general lack of knowledge of the laws governing the interaction of these two ever-present forces of heredity and environment wherever there is life. My own studies have led me to be assured that heredity is only the sum of all past environment, in other words environment is the architect of heredity; and I am assured of another fact: acquired characters are transmitted andâeven furtherâthat all characters which are transmitted have been acquired..."
"But with those who are mentally defectiveâah, here is the hardest question of all!âwhat shall be done with them? ...In the case of human beings in whom the light of reason does not burn... shall they be eliminated from the race? Go to the mother of an imbecile child and get your answer. ...For these helpless unfortunates, as with those who are merely unfortunate from environment, I should enlist the best and broadest state aid."
"When certain hereditary tendencies are almost indelibly ingrained, environment will have a hard battle to effect a change in the child; but that a change can be wrought by the surroundings we all know. The particular subject may at first be stubborn against these influences, but repeated application of the same modifying forces in succeeding generations will at last accomplish the desired object in the child as it does in the plant."
"In child rearing environment is equally essential with heredity."
"Here appears a child plainly not normal, what shall we do with him? Shall we, as some have advocated, even from Spartan days, hold that the weaklings should be destroyed? No. In cultivating plant life, while we destroy much that is unfit, we are constantly on the lookout for what has been called the abnormal, that which springs apart in new lines. How many plants are there in the world to-day that were not in one sense once abnormalities? No; it is the influence of cultivation, of selection, of surroundings, of environment, that makes the change from the abnormal to the normal. From the children we are led to call abnormal, may come, under wise cultivation and training, splendid normal natures."
"Pick out any trait you want in your child... By surrounding this child with sunshine from the sky and your own heart, by giving the closest communion with nature, by feeding this child well-balanced, nutritious food, by giving it all that is implied in healthful environmental influences, and by doing all in love, you can thus cultivate in the child and fix there for all its life all of these traits."
"There is not a single desirable attribute which, lacking in a plant, may not be bred into it. Choose what improvement you wish in a flower, a fruit, or a tree, and by crossing, selection, cultivation, and persistence you can fix this desirable trait irrevocably."
"Do not be cross with the child; you cannot afford it. If you are cultivating a plant, developing it into something finer and nobler, you must love it, not hate it; be gentle with it, not abusive; be firm, never harsh. I give the plants upon which I am at work in a test, whether a single one or a hundred thousand, the best possible environment. So should it be with a child, if you want to develop it in right ways. Let the children have music, let them have pictures, let them have laughter, let them have a good time; not an idle time but one full of cheerful occupation. Surround them with all the beautiful things you can. Plants should be given sun and air and the blue sky; give them to your boys and girls. ...for all the years. We cannot treat a plant tenderly one day and harshly the next; they cannot stand it. Remember that you are training not only for to-day, but for all the future, for all posterity."
"Look at the material on which to draw. Here is the North, powerful, virile, aggressive, blended with the luxurious, ease-loving, more impetuous South. Again you have the merging of a cold phlegmatic temperament with one mercurial and volatile. Still again the union of great native mental strength, developed or undeveloped, with bodily vigor, but with inferior mind. See, too, what a vast number of environmental influences have been at work in social relations, in climate, in physical surroundings. Along with this we must observe the merging of the vicious with the good, the good with the good, the vicious with the vicious."
"Let me lay emphasis on the opportunity now presented in the United States for observing and, if we are wise, aiding in what I think it fair to say is the grandest opportunity ever presented of developing the finest race the world has ever known out of the vast mingling of races brought here by immigration."