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April 10, 2026
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"Everything great and splendid is founded on power and wealth. They are the basis of beauty. This is why the rebel and the anarchic protester who decries all of history and all the works of past centuries because he sees in them only the skills and the threat of domination is making a mistake. He sees alienated forms, but not the greatness within. The rebel can only see to the end of his own ‘private’ consciousness, which he levels against everything human, confusing the oppressors with the oppressed masses, who were nevertheless the basis and the meaning of history and past works. Castles, palaces, cathedrals, fortresses, all speak in their various ways of the greatness and the strength of the people who built them and against whom they were built. This real greatness shines through the fake grandeur of rulers and endows these buildings with a lasting ‘beauty’. The bourgeoisie is alone in having given its buildings a single, over-obvious meaning, impoverished, deprived of reality: that meaning is abstract wealth and brutal domination; that is why it has succeeded in producing perfect ugliness and perfect vulgarity. The man who denigrates the past, and who nearly always denigrates the present and the future as well, cannot understand this dialectic of art, this dual character of works and of history. He does not even sense it. Protesting against bourgeois stupidity and oppression, the anarchic individualist is enclosed in ‘private’ consciousness, itself a product of the bourgeois era, and no longer understands human power and the community upon which that power is founded. The historical forms of this community, from the village to the nation, escape him. He is, and only wants to be, a human atom (in the scientifically archaic sense of the word, where ‘atom’ meant the lowest isolatable reality). By following alienation to its very extremes he is merely playing into the hands of the bourgeoisie. Embryonic and unconscious, this kind of anarchism is very widespread. There is a kind of revolt, a kind of criticism of life, that implies and results in the acceptance of this life as the only one possible. As a direct consequence this attitude precludes any understanding of what is humanly possible."
"The method of Marx and Engels consists precisely in a search for the link which exists between what men think, desire, say and believe for themselves and what they are, what they do. This link always exists. It can be explored in two directions. On the one hand, the historian or the man of action can proceed from ideas to men, from consciousness to being - i.e. towards practical, everyday reality - bringing the two into confrontation and thereby achieving archieving criticism of ideas by action and realities. That is the direction which Marx and Engels nearly always followed in everything they wrote; and it is the direction which critical and constructive method must follow initially if it is to take a demonstrable shape and achieve results. But it is equally possible to follow this link in another direction, taking real life as the point of departure in an investigation of how the ideas which express it and the forms of consciousness which reflect it emerge. The link, or rather the network of links between the two poles will prove to be complex. It must be unravelled, the thread must be carefully followed. In this way we can arrive at a criticism of life by ideas which in a sense extends and completes the first procedure."
"The 'meaning' of life is not to be found in anything other than that life itself. It is within it, and there is nothing beyond that. 'Meaning' cannot spill over from being; it is the direction, the movement of being, and nothing more. The 'meaning' of a proletarian's life is to be found in that life itself: in its despair, or conversely in its movement towards freedom, if the proletarian participates in the life of the proletariat, and if that life involves continuous, day-to-day action (trade-union, political...)."
"Appearance and reality [...] are not separated like oil and water in a vessel, but rather amalgamated like water and wine. To separate them, we must analyse them in the most 'classic' sense of the word: the elements of the mixture must be isolated."
"To see things properly, it is not enough simply to look. People who look at life - purely as witnesses, spectators - are not rare; and one of the strangest lessons to be learnt from our literature is that professional spectators, judges by vocation and witnesses by predestination, contemplate life with less understanding and grasp of its rich content than anyone else. There really is no substitution for participation!"
"'Change life! 'Change society!' These precepts mean nothing without the production of an appropriate space. … new social relationships call for a new space, and vice versa."
"Pressure from below must therefore also confront the state in its role as organiser of space, as the power that controls urbanization, the construction of buildings and spatial planning in general. The state defends class interests while simultaneously setting itself above society as a whole, and its ability to intervene in space can and must be turned back against it, by grass-roots opposition, in the form of counter-plans and counter-projects designed to thwart strategies, plans and programmes imposed from above."
"The most remarkable aspect of the transition we are living through is not so much the passage from want to affluence as the passage from labour to leisure"
"It is through knowledge that the proletarian liberates himself and begins actively superseding his condition. Moreover in this effort to attain knowledge and awareness, he is forced to assimilate complex theories (economic, social, political...), i.e. to integrate the loftiest findings of science and culture into his own consciousness. On the other hand the petty bourgeois and bourgeois, as such, are barred access to the human. For them to become humanized, they must break with themselves, reject themselves, an endeavor which on an individual level is frequently real and pathetic … We should understand men in a human way, even if they are incomplete; conditions are not confined within precise, geometrically defined boundaries, but are the result of a multitude of obstinate and ever-repeated (everyday) causes. Attempts to escape from the bourgeois condition are not particularly rare; on the other hand, the failure of such attempts are virtually inevitable, precisely because it is not so much a question of suppression but of a complete break. (Among intellectuals, this notion of super session is frequently false and harmful; when they supersede themselves as petty-bourgeois or bourgeois intellectuals, they are often merely continuing in the same direction and following their own inclinations in the belief that they are 'superseding themselves'. So far from gaining a new consciousness, they are merely making the old one worse. There is nothing more unbearable than the intellectual who believes himself to be free and human, while in every action, gesture, word and thought he shows that he has never stepped beyond bourgeois consciousness.)"
"Socialism, when it attempts to predict or imagine the future (which Marx refused to do, since he conceived of a path, not a model), provides us merely with an improved form of labor (salaries and material conditions on the job)."
"Just as economic pressure from the base … is able to modify the production of surplus value, so pressure grounded in spatial practice is alone capable of modifying the apportionment of that surplus value — i.e. the distribution of the portion of social surplus production allotted to society's collective 'interests', to so-called social services. Such grass-roots pressure, if it is to be effective in this regard, cannot be confined to attacking the state qua guardian of the 'general interest'. For this state, born of the hegemony of a class, has as one of its functions — and a more and more significant function — the organization of space, the regularization of its flows, the control of its networks. It devotes to these purposes a considerable part of global surplus value, of the surplus production assigned to the running of society."
"In the Jacob-Monod model, signals from a cell's environment activate regulatory proteins that switch on the genes encoding particular proteins. This led [Philip] Goelet and me to wonder whether the crucial step in switching on long-term memory in sensitization might involve similar signals and similar gene regulatory proteins."
"Jacob and Monod not only outlined a theory of gene regulation, they also discovered the first regulators of gene transcription. These regulators come in two forms—repressors, genes that encode the regulatory proteins that shut genes off, and as later work showed, activators, genes that encode the regulatory proteins that turn genes on."
"One day, almost exactly 25 years ago - it was at the beginning of the bleak winter of 1940 - I entered ’s office at the Pasteur Institute. I wanted to discuss with him some of the rather surprising observations I had recently made. I was working then at the old Sorbonne, in an ancient laboratory that opened on a gallery full of stuffed monkeys. Demobilized in August in the Free Zone after the disaster of 1940, I had succeeded in locating my family living in the Northern Zone and had resumed my work with desperate eagerness. I interrupted work from time to time only to help circulate the first clandestine tracts. I wanted to complete as quickly as possible my doctoral dissertation, which, under the strongly biometric influence of Georges Teissier, I had devoted to the study of the kinetics of bacterial growth. Having determined the constants of growth in the presence of different carbohydrates, it occurred to me that it would be interesting to determine the same constants in paired mixtures of carbohydrates. From the first experiment on, I noticed that, whereas the growth was kinetically normal in the presence of certain mixtures (that is, it exhibited a single exponential phase), two complete growth cycles could be observed in other carbohydrate mixtures, these cycles consisting of two exponential phases separated by a complete cessation of growth."
"What I consider completely sterile is the attitude, for instance, of Bertalanffy who is going around and jumping around for years saying that all the analytical science and molecular biology doesn’t really get to interesting results; let’s talk in terms of general systems theory ... there cannot be anything such as general systems theory, it’s impossible. Or, if it existed, it would be meaningless."
"From then on I read avidly the first publications by the "phage-church", and when I entered Lwoff’s department at the Pasteur Institute in 1945, I was tempted to abandon enzyme adaptation in order to join the church myself and work with bacteriophage."
"If [the emergence of the human species] was unique, as may perhaps have been the appearance of life itself, then before it did appear its chances of doing so were infinitely slender. The universe was not pregnant with life nor the biosphere with man. Our number came up in the Monte Carlo game."
"The universe is not pregnant with life nor the biosphere with man. ... Man at last knows that he is alone in the unfeeling immensity of the universe, out of which he emerged only by chance. His destiny is nowhere spelled out, nor is his duty. The kingdom above or the darkness below: it is for him to choose."
"There is in science, however, quite a gap between belief and certainty. But would one ever have the patience to wait and to establish the certainty if the inner conviction were not already there?"
"Jacques Monod... published a paper entitled "Genetic Regulatory Mechanisms in the Synthesis of Protein." Using bacteria as a model system, they made the remarkable discovery that genes can be regulated—that is, they can be switched on and off like a water faucet."
"Jacob and Monod found that in bacteria, genes are switched on and off by other genes. This led them to distinguish between effector genes and regulatory genes. Effector genes encode effector proteins... which mediate specific cellular functions. Regulatory genes encode proteins called regulatory proteins, which switch the effector genes on or off."
"The first scientific postulate is the objectivity of nature: nature does not have any intention or goal."
"Anything found to be true of E. coli must also be true of elephants."
"We might begin with Jacques Monod. Monod was a great figure whose scientific work I much admire, and was, essentially, the creator of modern molecular biology. His reflections on ethics, however, were of a different quality. (...) Monod's conclusions stem from his opinion that the only other possible way to account for the origin of morals - apart from ascribing them to human invention - is by animistic or anthropomorphic accounts such as are given in many religions. And it is indeed true that 'for mankind as a whole all religions have been intertwined with the anthropomorphic view of the deity as a father, friend or potentate to whom men must do service, pray, etc.' (M. R. Cohen, 1931:112). This aspect of religion I can as little accept as can Monod and the majority of natural scientists. It seems to me to lower something far beyond our comprehension to the level of a slightly superior manlike mind."
"Entirety exists within me as exuberance … in empty longing … in … the desire to burn with desire."
"Life is whole only when it isn’t subordinate to a specific object that exceeds it. In this way, the essence of entirety is freedom."
"It is the positive practice of freedom, not the negative struggle against particular oppression, that has lifted me above a mutilated existence."
"I cannot exist entirely except when somehow I go beyond the stage of action. Otherwise I’m a soldier, a professional, a man of learning, not a “total human being.” The fragmentary state of humanity is basically the same as the choice of an object. When you limit your desires to possessing political power, for instance, you act and know what you have to do. … You insert your existence advantageously into time. Each of your moments becomes useful. With each moment, the possibility is given you to advance to some chosen goal, and your time becomes a march toward that goal—what’s normally called living. … Every action makes you a fragmentary existence. I hold on to my nature as an entirety only by refusing to act—or at least by denying the superiority of time, which is reserved for action."
"What causes [fragmentation] if not a need to act that specializes us and limits us to the horizon of a particular activity? Even if it turns out to be for the general interest (which generally isn’t true), the activity that subordinates each of our aspects to a specific result suppresses our being as an entirety. Whoever acts substitutes a particular end for what he or she is, as a total being."
"Humanity-attached-to-the-task-of-changing-the-world, which is only a single and fragmentary aspect of humanity, will itself be changed in humanity-as-entirety."
"The total person is first disclosed … in areas of life that are lived frivolously."
"Nothing radically changes when instead of human satisfaction, we think of the satisfaction of some heavenly being! God’s person displaces the problem and does not abolish it."
"Concern for this or that limited good can sometimes lead to the summit... But this occurs in a roundabout way. Moral ends … are distinct from any excesses they occasion. States of glory and moments of sacredness surpass results intentionally sought."
"An extreme, unconditional human yearning was expressed for the first time by Nietzsche independently of moral goals or of serving God. … Ardor that doesn’t address a dramatically articulated moral obligation is a paradox. … If we stop looking at states of ardor as simply preliminary to other and subsequent conditions grasped as beneficial, the state I propose seems a pure play of lightning, merely an empty consummation. Lacking any relation to material benefits such as power or the growth of the state (or of God or a Church or a party), this consuming can’t even be comprehended. … I’ll have to face the same difficulties as Nietzsche—putting God and the good behind him, though all ablaze with the ardor possessed by those who lay down their lives for God or the good. … I’ll admit that moral investigations that aim to surpass the good lead first of all to disorder."
"I remain in intolerable non-knowledge, which has no other way out than ecstasy itself."
"It is through an “intimate cessation of all intellectual operations” that the mind is laid bare. If nor, discourse maintains it in its little complacency. … The difference between inner experience and philosophy resides principally in this: that in experience, … what counts is no longer the statement of wind, but the wind."
"In the helter-skelter of this book, I didn’t develop my views as theory. In fact, I even believe that efforts of that kind are tainted with ponderousness. Nietzsche wrote “with his blood,” and criticizing, or, better, experiencing him means pouring out one’s lifeblood. … It was only with my life that I wrote the Nietzsche book that I had planned."
"Existence as entirety remains beyond any one meaning—and it is the conscious presence of humanness in the world inasmuch as this is nonmeaning, having nothing to do other than be what it is, no longer able to go beyond itself or give itself some kind of meaning through action."
"Inner experience … is not easily accessible and, viewed from the outside by intelligence, it would even be necessary to see in it a sum of distinct operations, some intellectual, others aesthetic, yet others moral. … It is only from within, lived to the point of terror, that it appears to unify that which discursive thought must separate."
"The advance of intelligence diminished, as a secondary consequence, the “possible” in a realm which appeared foreign to intelligence: that of inner experience. To say “diminished” is even to say too little. The development of intelligence leads to a drying up of life which, in return, has narrowed intelligence. It is only if I state this principle: “inner experience itself is authority” that I emerge from this impotence."
"Philosophy … finds itself to be no longer anything but the heir to a fabulous mystical theology, but missing a God and wiping the slate clean."
"Experience is, in fever and anguish, the putting into question (to the test) of that which a man knows of being. Should he in this fever have any apprehension whatsoever, he cannot say: “I have seen God, the absolute, or the depths of the universe”; he can only say “that which I have seen eludes understanding”—and God, the absolute, the depths of the universe are nothing if they are not categories of the understanding. If I said decisively, “I have seen God,” that which I see would change. Instead of the inconceivable unknown—wildly free before me, leaving me wild and free before it—there would be a dead object and the thing of the theologian, to which the unknown would be subjugated."
"By inner experience I understand that which one usually calls mystical experience: the states of ecstasy, of rapture, at least of meditated emotion. But I am thinking less of confessional experience, to which one has had to adhere up to now, than of an experience laid bare, free of ties, even of an origin, of any confession whatever. This is why I don’t like the word mystical."
"Inner experience, unable to have principles either in dogma (a moral attitude), or in science (knowledge can be neither its goal nor its origin), or in a search of enriching states (an experimental, aesthetic attitude), it cannot have any other concern nor other goal than itself. Opening myself to inner experience, I have placed in it all value and authority. Henceforth I can have no other value, no other authority (in the realm of mind). Value and authority imply the discipline of a method, the existence of a community. I call experience a voyage to the end of the possible of man. Anyone may choose not to embark on this voyage, but if he does embark on it, this supposes the negation of the authorities, the existing values which limit the possible. By virtue of the fact that it is negation of other values, other authorities, experience, having a positive existence, becomes itself positively value and authority. Inner experience has always had objectives other than itself in which one invested value and authority. … If God, knowledge, and suppression of pain were to cease to be in my eyes convincing objectives, … would inner experience from that moment seem empty to me, henceforth impossible without justification? ... I received the answer [from Blanchot]: experience itself is authority."
"The difficulty—that contestation must be done in the name of an authority—is resolved this: I contest in the name of contestation what experience itself is."
"Anyone wanting slyly to avoid suffering identifies with the entirety of the universe, judges each thing as if he were it. In the same way, he imagines, at bottom, that he will never die. We receive these hazy illusions like a narcotic necessary to bear life. But what happens to us when, disintoxicated, we learn what we are? Lost among babblers in a night in which we can only hate the appearance of light which comes from babbling. The self-acknowledged suffering of the disintoxicated is the subject of this book."
"There is no communication more profound,” he claims. “[T]wo beings are lost in a convulsion that binds them together. But they only communicate when losing a part of themselves. Communication ties them together with wounds, where their unity and integrity dissipate in fever."
"We have in fact only two certainties in this world—that we are not everything and that we will die. To be conscious of not being everything, as one is of being mortal, is nothing. But if we are without a narcotic, an unbreathable void reveals itself. I wanted to be everything, so that falling into this void, I might summon my courage and say to myself: “I am ashamed of having wanted to be everything, for I see now that it was to sleep.” From that moment begins a singular experience. The mind moves in a strange world where anguish and ecstasy coexist."
"The analysis of laughter had opened to me points of contact between the fundamentals of a communal and disciplined emotional knowledge and those of discursive knowledge."
"Love expresses a need for sacrifice each unity must lose itself in some other which exceeds it. In erotic frenzy the being is led to tear itself apart and lose itself."