"Welcome to the City of Frank. 85 trillion cells and still growing, which is getting to be a big problem. Y'see, when a body gets this old and congested, there's a lot more upkeep. And in Frank, everybody's workin' overtime. I should know. The name's Jones. Osmosis Jones. I'm a cop. That's my partner Drix. He's a pill, but he's cool. We got a tip that Scarlet Fever's visiting a chop shop south of the stomach, below the beltway, deep in bowel town. I've been after this bad booty bacteria half my life. He wasn't gettin' away this time."
January 1, 1970
https://en.wikiquote.org/wiki/First_lines_in_animated_TV_shows