"CrO2·C5H5N is a mild reagent for the oxidation of alcohols that contain acid-sensitive groups. … Primary and secondary alcohols are readily oxidized in CH2Cl2 utilizing 1 to 1.5 equivalents of PCC. … PDC is soluble in H2O, DMF, and DMSO but sparingly soluble in CH2Cl2 or CHCl3. The reagent is less acidic than PCC. Hence, oxidations in CH2Cl2 can be carried out under nearly neutral conditions. This permits the conversion of primary alcohols containing acid-sensitive groups into the corresponding aldehydes or ketones, as illustrated below."