"The biologists argue that the number of evolutionary pathways leading from one-celled organisms to intelligent beings is minuscule when compared with the total number of evolutionary pathways, and thus even if we grant the existence of life on 109 to 1010 planets in our Galaxy, the probability that intelligence has arisen... [there] on any planet but our own is still very small. I agree..."
January 1, 1970
https://en.wikiquote.org/wiki/Frank_J._Tipler