biologists-from-austria

"The birth of modern genetics was due to the discoveries of Gregor Mendel (1823–1884), an Augustinian monk who taught natural science to high school students in the town of Brno in Moravia (now part of the Czech Republic). Mendel’s greatest insight was to focus on discrete, clear-cut characters rather than measuring continuously variable properties, such as height or weight. Mendel used pea plants and studied characteristics such as whether the seeds were smooth or wrinkled, whether the flowers were red or white, and whether the pods were yellow or green, etc. When asked if any particular individual inherited these characteristics from its parents, Mendel could respond with a simple “yes” or “no,” rather than “maybe” or “partly.” Such clear-cut, discrete characteristics are known as Mendelian characters(Fig. 1.01)."

"It is willingly granted that by cultivation the origination of new varieties is favored, and that by man's labor many varieties are acquired which, under natural conditions, would be lost; but nothing justifies the assumption that the tendency to formation of varieties is so extraordinarily increased that the species speedily lose all stability, and their offspring diverge into an endless series of extremely variable forms. Were the change in the conditions the sole cause of variability we might expect that those cultivated plants which are grown for centuries under almost identical conditions would again attain constancy."

"I am inclined to regard the separation of parental traits in the progeny of hybrids in Pisum as complete and thus permanent. The progeny of hybrids carries one or the other of the parental traits, or the hybrid form of the two; I have never observed gradual transitions between the parental traits or a progressive approach towards one of them. The course of development consists simply in this; that in each generation the two parental traits appear, separated and unchanged, and there is nothing to indicate that one of them has either inherited or taken over anything from the other"

"Investigations that before had only been imagined as desirable now became easy to pursue, and questions as to the genetic inter-relations and compositions of varieties can now be definitely answered. Without prejudice to what the future may disclose whether by way of limitation or extension of the Mendelian method, it can be declared with confidence and certainty that we have now the means of beginning an analysis of living organisms, and distinguishing many of the units or factors which essentially determine and cause the development of their several attributes. Briefly put, the essence of the Mendelian lies in the discovery of the existence of unit characters or factors."

"Gärtner by the results of these transformation experiments, was led to oppose the opinion of those naturalists who dispute the stability of plant species and believe in a continuous evolution of vegetation. He perceives in the complete transformation of one species into another an indubitable proof that species are fixed within limits beyond which they cannot change."

"Of the experiments of previous years, those dealing with Matthiola annua and glabra, Zea, and Mirabilis were concluded last year. Their hybrids behave exactly like those of Pisum. Darwin's statements concerning hybrids of the genera mentioned in The variation of animals and plants under domestication, based on reports of others, need to be corrected in many respects."

"Jesus appeared to the disciples after the resurrection in various forms. He appeared to Mary Magdalene so that they might take him for a gardener. Very ingeniously these manifestation of Jesus is to our minds difficult to penetrate. (He appears) as a gardener. The gardener plants seedlings in prepared soil. The soil must exert a physical and chemical influence so that the seed of the plant can grow. Yet this is not sufficient. The warmth and light of the sun must be added, together with rain, in order that growth may result. The seed of supernatural life, of sanctifying grace, cleanses from sin, so preparing the soul of man, and man must seek to preserve this life by his good works. He still needs the supernatural food, the body of the Lord, which received continually, develops and brings to completion of the life. So natural and supernatural must unite to the realization of the holiness to the people. Man must contribute his minimum work of toil, and God gives the growth. Truly, the seed, the talent, the grace of God is there, and man has simply to work, take the seeds to bring them to the bankers. So that we "may have life, and abundantly"."

"It concerns the opinion of Naudin and Darwin that a single pollen grain does not suffice for fertilization of the ovule. I used Mirabilis Jalappa for an experimental plant, as Naudin had done; the result of my experiment is, however, completely different. From fertilizations with single pollen grains, I obtained eighteen well-developed seeds, and from these an equal number of plants, of which ten are already in bloom"

"Experience of artificial fertilization, such as is effected with ornamental plants in order to obtain new variations in colour, has led to the experiments which will here be discussed. The striking-regularity with which the same hybrid forms always reappeared whenever fertilisation took place between the same species induced further experiments to be undertaken, the object of which was to follow up the developments of the hybrids in their progeny."

"Every organism represents a system, by which term we mean a complex of elements in mutual interaction. From this obvious statement the limitations of the analytical and summative conceptions must follow. First, it is impossible to resolve the phenomena of life completely into elementary units; for each individual part and each individual event depends not only on conditions within itself, but also to a greater or lesser extent on the conditions within the whole, or within superordinate units of which it is a part. Hence the behavior of an isolated part is, in general, different from its behavior within the context of the whole... Secondly, the actual whole shows properties that are absent from its isolated parts."

"Unsere Aufgabe muß es vielmehr sein, die Lebewesen als Systeme besonderer Art von in dynamischer Wechselwirkung stehenden Elementen zu betrachten und die hier geltenden Systemgesetze zu ermitteln, welche die Ordnung aller Teile und Vorgänge untereinander beherrschen. Notwendig ist sowohl die Untersuchung der Teile und Vorgänge als auch der Beziehungen, in denen diese zueinander und zum Ganzen stehen."

"Therefore, general systems theory should be, methodologically, an important means of controlling and instigating the transfer of principles from one field to another, and it will no longer be necessary to duplicate or triplicate the discovery of the same principles in different fields isolated from the other."

"From the physical point of view the characteristic state of the living organism is that of an open system. A system is closed if no material enters or leaves it; it is open if there is import and export and, therefore, change of the components. Living systems are open systems, maintaining themselves in exchange of materials with environment, and in continuous building up and breaking down of their components."

"What we call growth of even a simple organism is a tremendously complex phenomenon from the biochemical, physiological, cytological, and morphological viewpoints."

"Apparently, the isomorphisms of laws rest in our cognition on the one hand, and in reality on the other."

"We realize, however, that all scientific laws merely represent abstractions and idealizations expressing certain aspects of reality. Every science means a schematized picture of reality, in the sense that a certain conceptual construct is unequivocally related to certain features of order in reality;"

"A system can be defined as a set of elements standing in interrelations. Interrelation means that elements, p, stand in relations, R, so that the behavior of an element p in R is different from its behavior in another relation, R’. If the behaviors in R and R’ are not different, there is no interaction, and the elements behave independently with respect to the relations R and R’."

"Can civilizations and cultures be considered as systems? It seems, therefore, that a general theory of systems would be a useful tool providing, on the one hand, models that can be used in, and transferred different fields, and safeguarding, on the other hand, from vague analogies which often have marred the progress in these fields."

"Modern science is characterized by its ever-increasing specialization, necessitated by the enormous amount of data, the complexity of techniques and of theoretical structures within every field. Thus science is split into innumerable disciplines continually generating new subdisciplines. In consequence, the physicist, the biologist, the psychologist and the social scientist are, so to speak, encapsulated in their private universes, and it is difficult to get word from one cocoon to the other."

"There appears to exist a general systems laws which apply to any system of a certain type, irrespective of the particular properties of the system and of the elements involved."

"We find systems which by their very nature and definition are not closed systems. Every living organism is essentially an open system. It maintains itself in a continuous inflow and outflow, a building up and breaking down of components, never being, so long as it is alive, in a state of chemical and thermodynamic equilibrium but maintained in a so-called steady state which is distinct from the latter."

"While we can conceive of a sum [or aggregate] as being composed gradually, a system as a total of parts with its [multiplicative] interrelations has to be conceived of as being composed instantly."

"From the methodological standpoint, however, we see that 'mechanism' and 'vitalism' by no means form the mutually exclusive disjunction they have been supposed to do. If a 'non-mechanist' wishes to deny the assumption of methodological mechanism that biological explanations must also be physico-chemical ones, it is obviously by no means intended that the required explanation must be 'vitalistic', i.e. involving the assumption that in living organisms factors analogous to psychical ones are 'at work'. A 'non-mechanistic' theory which is not all 'vitalistic' thus appears to be logically possible, and if we make a critical study of mechanism and vitalism this possibility will be seen to be of special importance."

"From the statements we have made, a stupendous perspective emerges, a vista towards a hitherto unsuspected unity of the conception of the world. Similar general principles have evolved everywhere, whether we are dealing with inanimate things, organisms, mental or social processes. What is the origin of these correspondences? We answer this question by the claim for a new realm of science, which we call General System Theory. It is a logico-mathematical field, the subject matter of which is the formulation and derivation of those principles which hold for systems in general. A "system" can be defined as a complex of elements standing in interaction. There are general principles holding for systems, irrespective of the nature of the component elements and of the relations or forces between them."

"The science of life has nowadays to a certain extent become a crossroad, in which the contemporary intellectual developments converge. The biological theories have acquired a tremendous ideological [weltanschauliche], yes even public and political significance... The condition of biology, problematic in many respects, has led to the situation that the “philosophies of life” were until now by no means satisfactory from the scientific as much as the practical point of view; we see all the more clearly the importance of the theoretical clarification of biology."

"The characteristic of life does not lie in a distinctiveness of single life processes. [Lebensvorgänge], but rather in a certain order among all the processes."

"Mechanism... provides us with no grasp of the specific characteristics of organisms, of the organization of organic processes among one another, of organic 'wholeness', of the problem of the origin of organic 'teleology', or of the historical character of organisms... We must therefore try to establish a new standpoint which — as opposed to mechanism — takes account of organic wholeness, but... treats it in a manner which admits of scientific investigation."

"Animal growth can be considered as a result of a counteraction of synthesis and destruction, of the anabolism and catabolism of the building materials of the body. There will be growth so long as building up prevails over breaking down."

"General Systems Theory... possibly the model of the world as a great organization can help to reinforce the sense of reverence for the living which we have almost lost."

"Today our main problem is that of organized complexity. Concepts like those of organization, wholeness, directiveness, teleology, control, self-regulation, differentiation and the like are alien to conventional physics. However, they pop up everywhere in the biological, behavioural and social sciences, and are, in fact, indispensable for dealing with living organisms or social groups. Thus, a basic problem posed to modern science is a general theory of organization."

"You cannot sum up the behavior of the whole from the isolated parts, and you have to take into account the relations between the various subordinate systems which are super-ordinated to them in order to understand the behavior of the parts."

"If someone were to analyze current notions and fashionable catchwords, he would find "systems" high on the list. The concept has pervaded all fields of science and penetrated into popular thinking, jargon and mass media."

"We are confronted with problems of organized complexity... organization runs through all levels of reality and science."

"We are seeking for another basic outlook - the world as organization. This would profoundly change the categories of our thinking and influence our practical attitudes. We must envision the biosphere as a whole with mutually reinforcing or mutually destructive interdependencies."

"General systems theory (in the narrow sense of the term) is a discipline concerned with the general properties and laws of “systems”. A system is defined as a complex of components in interaction, or by some similar proposition. Systems theory tries to develop those principles that apply to systems in general, irrespective of the nature of the system, of their components, and of the relations or “forces” between them. The system components need not even be material, as, for example, in the system analysis of a commercial enterprise where components such as buildings, machines, personnel, money and “good will” of customers enter."

"Systems thinking plays a dominant role in a wide range of fields from industrial enterprise and armaments to esoteric topics of pure science. Innumerable publications, conferences, symposia and courses are devoted to it. Professions and jobs have appeared in recent years which, unknown a short while ago, go under names such as systems design, systems analysis, systems engineering and others."

"Higher, directed forms of energy (e.g., mechanical, electric, chemical) are dissipated, that is, progressively converted into the lowest form of energy, i.e., undirected heat movement of molecules; chemical systems tend toward equilibria with maximum entropy; machines wear out owing to friction; in communication channels, information can only be lost by conversion of messages into noise but not vice versa, and so forth."

"Classical science in its diverse disciplines, be it chemistry, biology, psychology or the social sciences, tried to isolate the elements of the observed universe - chemical compounds and enzymes, cells, elementary sensations, freely competing individuals, what not -- expecting that, by putting them together again, conceptually or experimentally, the whole or system - cell, mind, society - would result and be intelligible. Now we have learned that for an understanding not only the elements but their interrelations as well are required: say, the interplay of enzymes in a cell, of many mental processes conscious and unconscious, the structure and dynamics of social systems and the like."

"Teleologie ist … ein Ausfluss der Systemgesetzlichkeit und damit ein legitimer Gegenstand naturwissenschaftlicher Forschung"

"The system problem is essentially the problem of the limitation of analytical procedures in science. This used to be expressed by half-metaphysical statements, such as emergent evolution or ‘the whole is more than the sum of its parts,’ but has a clear operational meaning."

"It is necessary to study not only parts and processes in isolation, but also to solve the decisive problems found in organization and order unifying them, resulting from dynamic interaction of parts, and making the the behavior of the parts different when studied in isolation or within the whole."

"Thus, there exist models, principles, and laws that apply to generalized systems or their subclasses, irrespective of their particular kind, the nature of their component elements, and the relations or „forces‟ between them. It seems legitimate to ask for a theory, not of systems of a more or less special kind, but of universal principles applying to systems in general. In this way, we postulate a new discipline called General Systems Theory. Its subject matter is the formulation and derivation of those principles, which are valid for „systems‟ in general."

"What in the whole denotes a causal equilibrium process, appears for the part as a teleological event."

"Major aims of general theory: (1) There is a general tendency toward integration in the various sciences, natural and social. (2) Such integration seems to be centered in a general theory of systems. (3) Such theory may be an important means for aiming at exact theory in the nonphysical fields of science. (4) Developing unifying principles running "vertically" through the universe of the individual sciences, this theory brings us nearer the goal of the unity of science. (5) This can lead to a much-needed integration in scientific education."

"Our conception is that of a theory about the system in an inertial state... if the organism is a system in an inertial state, as our law expresses it, the metabolic processes generally have to follow the established system; the ever progressing findings must replace the general expression of 'a system in an inertial state' by a more and more detailed knowing about the nature of this system and its chemical, osmotic, fermentive system conditions."

"The general notion in communication theory is that of information. In many cases, the flow of information corresponds to a flow of energy, e.g. if light waves emitted by some objects reach the eye or a photoelectric cell, elicit some reaction of the organism or some machinery, and thus convey information."

"The rule is derived inductively from experience, therefore does not have any inner necessity, is always valid only for special cases and can anytime be refuted by opposite facts. On the contrary, the law is a logical relation between conceptual constructions; it is therefore deductible from upper [übergeordnete] laws and enables the derivation of lower laws; it has as such a logical necessity in concordance with its upper premises; it is not a mere statement of probability, but has a compelling, apodictic logical value once its premises are accepted"

"The characteristic of the organism is first that it is more than the sum of its parts and second that the single processes are ordered for the maintenance of the whole."

"Wholeness [Ganzheit], Gestalt, is the primary attribute of life."

"There are correspondences in the principles which govern the behavior of entities that are intrinsically widely different. These correspondences are due to the fact that they all can be considered, in certain aspects, "systems," that is, complexes of elements standing in interaction. [It seems] that a general theory of systems would be a useful tool providing, on the one hand, models that can be used in, and transferred to, different fields, and safeguarding, on the other hand, from vague analogies which often have marred the progress in these fields."