"The first erotic component is in feeding and sucking and I tried not to deal too much with it because it's always the direction that Vampire films take, so I was interested in taking another direction, to explore another side of vampirism. I wanted to make this film more of a dark fantasy, whether through the colours, the camera movement, the design, and the locations. The first Blade was very stylish and hip and yuppyish but in this one I wanted to show the dark side, the decadent side of their world, almost the despair of the vampire universe. I wanted to have of a wicked sense of humour and a graphic approach like a comic book. I wanted to go crazier and to have a better understanding of Blade's psychology and to understand why he is acting the way he does."

"In Cronos the Vampire was more about the meditation about time and immortality and here in Blade 2 it's the vampire at a basic level, vampires that are just animals that are greedy for blood, I created a new kind of vampires: the reapers that are designed genetically to be even stronger than the normal vampires. But we tried also to find some moments of empathy with these creatures, and there are moments when the reapers look pathetic, like junkies, and at moments when they have a broken arm or a dislocated head you almost feel sorry for them. So we tried to find beauty in these monsters and that's really horrific because it's almost real."

"Well, first we wanted to enhance Blade's romantic life, and get him laid! Also we wanted to make it a different environment. Initially it was going to be Vegas but Prague came up, for various reasons, and that's where we went. Also we wanted to make Blade feel more at ease with what he is."

"Karel Roden - Karel Kounen"

"Matt Schulze - Chupa"

"Luke Goss - Jared Nomak"

"Thomas Kretschmann - Eli Damaskinos"

"Ron Perlman - Reinhardt"

"Leonor Varela - Nyssa Damaskinos"

"Kris Kristofferson - Abraham Whistler"

"Norman Reedus - Scud"

"Wesley Snipes - Eric Brooks / Blade/'The Daywalker'"

"Faster. Sharper. Deadlier."

"One Man Still Has The Edge."

"Last time he fought against his sworn enemies... This time he will fight with them."

"Know The Mark."

"Vampire: [to Jared Nomak] This is a good news, bad news scenario, Jared: Good news for us, bad news for you."

"Vampire: [After realizing he is several floors above the ground] Fuck this shit!"

"Rush: Fuck! It's not silver, but it still hurts like hell!"

"Damaskinos: Who do you think God really favors in the web? The spider, or the fly?"

"Scud: Lock up your daughters boys and girls, the dark knight returns."

"[First lines, voiceover] In the movies, Dracula wears a cape, and some old English guy manages to save the day at the last minute with crosses and holy water. But everybody knows the movies are full of shit. The truth is, it started with Blade, and it ended with him. The rest of us were just along for the ride."

"Christopher Heyerdahl – Caulder"

"Patton Oswalt – Hedges"

"Natasha Lyonne – Sommerfield"

"James Remar – Ray Cumberland"

"Michael Rawlins – Wilson Hale"

"Françoise Yip – Virago"

"Paul Anthony – Wolfe"

"Paul Michael Levesque (Triple H) – Jarko Grimwood"

"Callum Keith Rennie – Asher Talos"

"John Michael Higgins – Dr. Edgar Vance"

"Mark Berry – Chief Martin Vreede"

"Parker Posey – Danica Talos"

"Ryan Reynolds – Hannibal King"

"Jessica Biel – Abigail Whistler"

"Dominic Purcell – Drake"

"Kris Kristofferson – Abraham Whistler"

"Wesley Snipes – Blade/Eric Brooks/"The Daywalker""

"He fought the forces of darkness alone … until now."

"The final hunt begins."

"Here's what I'll say about Blade: Trinity. If you watch - and by the way, I'm friends with the writer director, and he agrees with me on this. If you just sit and watch Blade: Trinity, it's a D-minus. It just doesn't work. But if you know what they went through to get that movie made. It is an A-plus. The fact that movie exists puts it above Citizen Kane. The fact that with all the craziness that went down. We were in Vancouver and Wesley Snipes was going crazy and he wouldn't come out of his trailer, and you'd walk by his trailer and this wall of pot stench would just be like "Whoa!" and kinda push you to the side, and then he would only answer to the name 'Blade', you couldn't call him. After awhile, he would communicate with post-its that he would give to the director, and each one he would sign "Blade"."

"[Last words] Funny, isn't it? My people were trying to create a new kind of vampire, when one already exists. I don't need to survive. The future of our race rests with you. You fought with honor. I respect that. So, allow me a parting gift. But know this: sooner, or later, the thirst always wins."

"[To Blade in his true form] Are you ready to die, "motherfucker"?"

"There is an old saying: kill one man, you're a murderer. Kill a million, a king. Kill them all, a god."

"FUCKING HANNIBAL KING! I should have ripped his bleeding heart out when I had the chance!"

"[Last lines] And Drake's final gift... Let's just say the FBI got their body... just wasn't the one they were banking on. Blade was still out there somewhere, doing what he did best. He was a weapon. His life was a war. And everybody knows the war never ends."

"[Last lines, original ending] And Blade? The virus didn't kill him. Because he was a hybrid, his heart never stopped beating. It simply slowed down. And so, he slept, waiting for the moment when he can walk the Earth again."

"[Danica lies dying of the Daystar Virus] Hang in there kitten, I'll get help."