University Of Cambridge Faculty

"Men will not always die quietly."

"But the dreams of designing diplomats do not always prosper, and we must trust the future."

"The division of the spoils between the victors will also provide employment for a powerful office, whose doorsteps the greedy adventurers and jealous concession hunters of twenty or thirty nations will crowd and defile."

"The future life of Europe was not their concern; its means of livelihood was not their anxiety. Their preoccupations, good and bad alike, related to frontiers and nationalities, to the balance of power, to imperial aggrandizements, to the future enfeeblement of a strong and dangerous enemy, to revenge, and to the shifting by the victors of their unbearable financial burdens on to the shoulders of the defeated."

"To see the British Prime Minister watching the company, with six or seven senses not available to ordinary men, judging character, motive, and subconscious impulse, perceiving what each was thinking and even what each was going to say next, and compounding with telepathic instinct the argument or appeal best suited to the vanity, weakness, or self-interest of his immediate auditor, was to realize that the poor President would be playing blind man's bluff in that party."

"The glory of the nation you love is a desirable end, — but generally to be obtained at your neighbor's expense."

"He had one illusion — France; and one disillusion — mankind, including Frenchmen, and his colleagues not least."

"I seek only to point out that the principle of accumulation based on inequality was a vital part of the pre-war order of Society and of progress as we then understood it, and to emphasize that this principle depended on unstable psychological conditions, which it may be impossible to recreate. It was not natural for a population, of whom so few enjoyed the comforts of life, to accumulate so hugely. The war has disclosed the possibility of consumption to all and the vanity of abstinence to many. Thus the bluff is discovered; the labouring classes may be no longer willing to forgo so largely, and the capitalist classes, no longer confident of the future, may seek to enjoy more fully their liberties of consumption so long as they last, and thus precipitate the hour of their confiscation."

"In writing thus I do not necessarily disparage the practices of that generation. In the unconscious recesses of its being Society knew what it was about. The cake was really very small in proportion to the appetites of consumption, and no one, if it were shared all round, would be much the better off by the cutting of it. Society was working not for the small pleasures of today but for the future security and improvement of the race,—in fact for "progress." If only the cake were not cut but was allowed to grow in the geometrical proportion predicted by Malthus of population, but not less true of compound interest, perhaps a day might come when there would be at last be enough to go round, and when posterity could enter into the enjoyment of our labors."

"The duty of "saving" became nine-tenths of virtue and the growth of the cake the object of true religion."

"The immense accumulations of fixed capital which, to the great benefit of mankind, were built up during the half century before the war, could never have come about in a Society where wealth was divided equitably."

"The disruptive powers of excessive national fecundity may have played a greater part in bursting the bonds of convention than either the power of ideas or the errors of autocracy."

"The great events of history are often due to secular changes in the growth of population and other fundamental economic causes, which, escaping by their gradual character the notice of contemporary observers, are attributed to the follies of statesmen or the fanaticism of atheists."

"The power to become habituated to his surroundings is a marked characteristic of mankind."

"I work for a Government I despise for ends I think criminal."

"If for example I had some idea, which as it turned out would be quite wrong, was going off of the tangent, Watson would tell me in no uncertain terms this was nonsense, and vice-versa. If he would have some idea I didn't like, and I would say so, this would shake his thinking about, and draw him back again. And in fact it is one of the requirements for collaborations of this sort, is you must be perfectly candid, one might almost say rude, to the person you're working with. It's useless working with somebody who is either much too junior than yourself or much too senior because then politeness creeps in. And this is the end of all real collaboration in science (giggles)."

"Conversations with Crick frequently upset Sir Lawrence Bragg, and the sound of his voice was often sufficient to make Bragg move to a safer room. Only infrequently would he come to tea in the Cavendish, since it meant enduring Crick's booming over the tea room."

"It was not until May of 1986 that I met Francis Crick, at a conference in San Diego. There was a big crowd, full of neuroscientists, but when it was time to sit down for dinner, Crick singled me out, seized me by the shoulders, sat me down next to him, and said, “Tell me stories!” I have no memory of what we ate, or anything else about the dinner, only that I told him stories about many of my patients, and that each one set off bursts of hypotheses, theories, suggestions for investigation in his mind. Writing to Crick a few days later, I said that the experience was “a little like sitting next to an intellectual nuclear reactor…. I never had a feeling of such incandescence.”"

"When he discovered the structure of DNA, Francis Crick immediately understood how genetic inheritance works, announcing in the Pub that evening that he understood the secret of life."

"Before I describe in more detail exactly what is involved in seeing, let me make three general remarks."

"Our brains have evolved mainly to deal with our body and its interactions with the world it senses to be around us. Is this world real? This is a venerable philosophical issue and I do not wish to be embroiled in the finely honed squabbles to which it has led. I merely state my own working hypothesis: that there is indeed an outside world, and that it is largely independent of our observing it. We can never fully know this outside world, but we can obtain approximate information about some aspects of its properties by using our senses and our brain."

"Philosophers have been especially concerned with the problem of consciousness—for example, how to explain the redness of red or the painfulness of pain. This is a very thorny issue. The problem springs from the fact that the redness of red that I perceive so vividly cannot be precisely communicated to another human being, at least in the ordinary course of events. If you cannot describe the properties of a thing unambiguously, you are likely to have some difficulty trying to explain these properties in reductionist terms."

"There is no form of prose more difficult to understand and more tedious to read than the average scientific paper."

"My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure,” I was supposed to have said in my molecular biology days. (I believe I was sailing at the time.) I think that one should approach these problems at all levels, as was done in molecular biology. Classical genetics is, after all, a black-box subject. The important thing was to combine it with biochemistry. In nature hybrid species are usually sterile, but in science the reverse is often true. Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts."

"The job of theorists, especially in biology, is to suggest new experiments. A good theory makes not only predictions, but surprising predictions that then turn out to be true. (If its predictions appear obvious to experimentalists, why would they need a theory?)"

"What is found in biology is mechanisms, mechanisms built with chemical components and that are often modified by other, later, mechanisms added to the earlier ones. While Occam's razor is a useful tool in the physical sciences, it can be a very dangerous implement in biology. It is thus very rash to use simplicity and elegance as a guide in biological research. While DNA could be claimed to be both simple and elegant, it must be remembered that DNA almost certainly originated fairly close to the origin of life when things were necessarily simple or they would not have got going. Biologists must constantly keep in mind that what they see was not designed, but rather evolved. It might be thought, therefore, that evolutionary arguments would play a large part in guiding biological research, but this is far from the case. It is difficult enough to study what is happening now. To figure out exactly what happened in evolution is even more difficult. Thus evolutionary achievements can be used as hints to suggest possible lines of research, but it is highly dangerous to trust them too much. It is all too easy to make mistaken inferences unless the process involved is already very well understood."

"Both of us had decided, quite independently of each other, that the central problem in molecular biology was the chemical structure of the gene."

"Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick."

"I argued that it was important not to place too much reliance on any single piece of experimental evidence. It might turn out to be misleading, as the 5.1 Å reflection undoubtedly was. Jim was a little more brash, stating that no good model ever accounted for all the facts, since some data was bound to be misleading if not plain wrong. A theory that did fit all the data would have been "carpentered" to do so and would thus be open to suspicion. (pp. 59-60)"

"Big questions get big answers."

"An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going. But this should not be taken to imply that there are good reasons to believe that it could not have started on the earth by a perfectly reasonable sequence of fairly ordinary chemical reactions. The plain fact is that the time available was too long, the many microenvironments on the earth's surface too diverse, the various chemical possibilities too numerous and our own knowledge and imagination too feeble to allow us to be able to unravel exactly how it might or might not have happened such a long time ago, especially as we have no experimental evidence from that era to check our ideas against."

"I wasn't aware of Chargaff's rules when he said them, but the effect on me was quite electric because I realized immediately that if you had this sort of scheme that John Griffith was proposing, of adenine being paired with thymine, and guanine being paired with cytosine, then you should get Chargaff's rules. I was very excited, but I didn't actually tell Chargaff because it was something I was doing with John Griffith. ... This was very exciting, and we thought "ah ha!" and we realized - I mean what anyone who is familiar with the history of science ought to realize - that when you have one-to-one ratios, it means things go to together. And how on Earth no one pointed out this simple fact in those years, I don't know."

"Unlike you and your colleagues I have formed the opinion that there is much substance to Jensen's arguments. In brief I think it likely that more than half the difference between the average I.Q. of American whites and Negroes is due to genetic reasons, and will not be eliminated by any foreseeable change in the environment. Moreover I think the social consequences of this are likely to be rather serious unless steps are taken to recognize the situation."

"And so to those of you who may be vitalists I would make this prophecy: what everyone believed yesterday, and you believe today, only cranks will believe tomorrow."

"The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry."

"The interpretation of quantum mechanics has been dealt with by many authors, and I do not want to discuss it here. I want to deal with more fundamental things."

"A good deal of my research work in physics has consisted in not setting out to solve some particular problems, but simply examining mathematical quantities of a kind that physicists use and trying to get them together in an interesting way regardless of any application that the work may have. It is simply a search for pretty mathematics. It may turn out later that the work does have an application. Then one has had good luck."

"God used beautiful mathematics in creating the world."

"It seems clear that the present quantum mechanics is not in its final form. Some further changes will be needed, just about as drastic as the changes made in passing from Bohr's orbit theory to quantum mechanics. Some day a new quantum mechanics, a relativistic one, will be discovered, in which we will not have these infinities occurring at all. It might very well be that the new quantum mechanics will have determinism in the way that Einstein wanted."

"My research work was based in pictures. I needed to visualise things and projective geometry was often most useful e.g. in figuring out how a particular quantity transforms under Lorentz transf[ormation]. When I came to publish the results I suppressed the projective geometry as the results could be expressed more concisely in analytic form."

"I went back to Cambridge at the beginning of October, 1925, and resumed my previous style of life, intense thinking about these problems during the week and relaxing on Sunday, going for a long walk in the country alone... It was during one of the Sunday walks in October, 1925, when I was thinking very much about this uv - vu, in spite of my intention to relax, that I thought about Poisson brackets. I remembered something which I had read up previously in advanced books of dynamics about these strange quantities, Poisson brackets, and from what I could remember, there seemed to be a close similarity between a Poisson bracket of two quantities, u and v, and the commutator uv - vu. The idea first came in a flash, I suppose, and provided of course some excitement, and then of course came the reaction "No, this is probably wrong." I did not remember very well the precise formula for a Poisson bracket, and only had some vague recollections. But there were exciting possibilities there, and I thought that I might be getting to some big new idea... it was a Sunday evening then and the libraries were all closed. I just had to wait impatiently through that night without knowing whether this idea was really any good or not, but still I think that my confidence gradually grew during the course of the night. The next morning I hurried along to one of the libraries as soon as it was open, and then I looked up Poisson brackets in Whittaker's Analytical Dynamics, and I found that they were just what I needed."

"I want to emphasize the necessity for a sound mathematical basis for any fundamental physical theory. Any philosophical ideas that one may have play only a subordinate role. Unless such ideas have a mathematical basis they will be ineffective."

"The measure of greatness in a scientific idea is the extent to which it stimulates thought and opens up new lines of research."

"If there is no complete agreement between the results of one's work and the experiment, one should not allow oneself to be too discouraged."

"I don't suppose that applies so much to other physicists; I think it’s a peculiarity of myself that I like to play about with equations, just looking for beautiful mathematical relations which maybe don’t have any physical meaning at all. Sometimes they do."

"It was a good description to say that it was a game, a very interesting game one could play. Whenever one solved one of the little problems, one could write a paper about it. It was very easy in those days for any second-rate physicist to do first-rate work. There has not been such a glorious time since then."

"With my assumption... life need never end. There is no decisive argument for deciding between [certain] assumptions. I prefer the one that allows the possibility of endless life. One may hope that some day the question will be decided by direct observation."

"In science one tries to tell people, in such a way as to be understood by everyone, something that no one ever knew before. But in the case of poetry, it's the exact opposite!"

"One of the most revered – and strangest – figures in the history of science."

"At the beginning of time the laws of Nature were probably very different from what they are now. Thus we should consider the laws of Nature as continually changing with the epoch, instead of as holding uniformly throughout space-time. This idea was first put forward by Milne, who worked it out on... assumptions... not very satisfying... we should expect them also to depend on position in space, in order to preserve the beautiful idea of the theory of relativity [that] there is fundamental similarity between space and time."