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April 10, 2026
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"God grant that by my persevering labours I may bring a little stone to the frail and ill-assured edifice of our knowledge of those deep mysteries of Life and Death where all our intellects have so lamentably failed."
"Though one discovery always surpasses another, and though the chemical and physical knowledge accumulated since his time has gone beyond all Lavoisier's dreams, his work, like that of Newton and a few other rare spirits, will remain ever young. Certain details will age, as do the fashions of another time, but the foundation, the method, constitute one of those great aspects of the human mind, the majesty of which is only increased by years."
"If perchance you should falter during the journey, a hand would be there to support you. If that should be wanting, God, who alone could take that hand from you, would Himself accomplish its work."
"La grandeur des actions humaines se mesure à l’inspiration qui les fait naître. Heureux celui qui porte en soi un Dieu, un idéal de la beauté et qui lui obéit : idéal de l’art, idéal de la science, idéal de la patrie, idéal des vertus de l’Évangile! Ce sont là les sources vives des grandes pensées et des grandes actions. Toutes s’éclairent des reflets de l’infini."
"Les Grecs avaient compris la mystérieuse puissance de ce dessous de choses. Ce sont eux qui nous ont légué un des plus beaux mots de notre langue, le mot enthousiasme. — Εν Θεος. — Un Dieu intérieur."
"Où sont les vraies sources de la dignité humaine, de la liberté et de la démocratie moderne, sinon dans la notion de l’infini devant laquelle tous les hommes sont égaux?"
"He who proclaims the existence of the Infinite, and none can avoid it — accumulates in that affirmation more of the supernatural than is to be found in all the miracles of all the religions; for the notion of the Infinite presents that double character that forces itself upon us and yet is incomprehensible. When this notion seizes upon our understanding we can but kneel ... I see everywhere the inevitable expression of the Infinite in the world; through it the supernatural is at the bottom of every heart. The idea of God is a form of the idea of the Infinite. As long as the mystery of the infinite weighs on human thought, temples will be erected for the worship of the Infinite, whether God is called Brahma, Allah, Jehovah, or Jesus; and on the pavement of these temples, men will be seen kneeling, prostrated, annihilated by the thought of the Infinite."
"The human spirit, driven by an invincible force, will never cease to ask: What is beyond? Does he want to stop either in time or in space? Since the point at which he has reigned is only a finite magnitude, greater only than all those who have preceded him, he has scarcely begun to think of it as the implacable question and always without being able to silence his curiosity. There is nothing to answer: there are spaces, times or magnitudes without limits. No one understands these words."
"Maintenant, messieurs, il y aurait un beau sujet à traiter : c’est celui du rôle, dans l’économie générale de la création, de quelques-uns de ces petits êtres qui sont les agents de la fermentation, les agents de la putréfaction, de la désorganisation de tout ce qui a eu vie il la surface du globe. Ce rôle est immense, merveilleux, vraiment émouvant. Un jour peut-être me sera-t-il donné de vous exposer ici quelques-uns de ces résultats. Dieu veuille que ce soit encore en présence à une aussi brillante assemblée!"
"No, there is now no circumstance known in which it can be affirmed that microscopic beings came into the world without germs, without parents similar to themselves. Those who affirm it have been duped by illusions, by ill-conducted experiments, spoilt by errors that they either did not perceive or did not know how to avoid."
"Et par conséquent, messieurs pourrais-je dire, en vous montrant ce liquide : J’ai pris dans l’immensité de la création ma goutte d’eau, et je l’ai prise toute pleine de la gelée féconde, c’est-à -dire, pour parler le langage de la science, toute pleine des éléments appropriés au développement des êtres inférieurs, Et j’attends, et j’observe, et je l’interroge, et je lui demande de vouloir bien recommencer pour moi la primitive création ; ce serait un si beau spectacle ! Mais elle est muette ! Elle est muette depuis plusieurs années que ces expériences sont commencées. Ah ! c’est que j’ai éloigné d’elle, et que j’éloigne encore en ce moment, la seule chose qu’il n’ait pas été donné à l’homme de produire, j’ai éloigné d’elle les germes qui flottent dans l’ait" j’ai éloigné d’elle la vie, car la vie c’est le germe et le germe c’est la vie. Jamais la doctrine de la génération spontanée ne se relèvera du coup mortel que Cette simple expérience lui porte."
"Comprenez-vous maintenant le lien qui existe entre la question des générations spontanées et ces grands problèmes que j'ai énumérés en commençant? Mais, messieurs, dans un pareil sujet, assez de poésie comme cela, assez de fantaisie et de solutions instinctives; il est temps que la science, la vraie méthode reprenne ses droits et les exerce. Il n'y a ici ni religion, ni philosophie, ni athéisme, ni matérialisme, ni spiritualisme qui tienne. Je pourrais même ajouter : Comme savant, peu m'importe. C'est une question de fait; je l'ai abordée sans idée préconçue, aussi prêt à déclarer, si l'expérience m'en avait imposé l'aveu, qu'il existe des générations spontanées, que je suis persuadé aujourd'hui que ceux qui les affirment ont un bandeau sur les veux."
"Great problems are now being handled, keeping every thinking man in suspense; the unity or multiplicity of human races; the creation of man 1,000 years or 1,000 centuries ago; the fixity of species, or the slow and progressive transformation of one species into another; the eternity of matter; the idea of a God unnecessary: such are some of the questions that humanity discusses nowadays."
"La génération spontanée, je la cherche sans la découvrir depuis vingt ans. Non, je ne la juge pas impossible. Mais quoi donc vous autorise à vouloir qu'elle ait été l'origine de la vie? Vous placez la matière avant la vie et vous faites la matière existante de toute éternité. Qui vous dit que, le progrès incessant de la science n'obligera pas les savants, qui vivront dans un siècle, dans mille ans, dans dix mille ans... à affirmer que la vie a été de toute éternité et non la matière.? Vous passez de la matière à la vie parce que votre intelligence actuelle, si bornée par rapport à ce que sera l'intelligence des naturalistes futurs, vous dit qu'elle ne peut comprendre autrement les choses. Qui m'assure que dans dix mille ans on ne considérera pas que c'est de la vie qu'on croira impossible de ne pas passer à la matière? Si vous voulez être au nombre des esprits scientifiques, s, qui seuls comptent, il faut vous débarrasser des idées et des raisonnements a priori et vous en tenir aux déductions nécessaires des faits établis et ne pas accorder plus de confiance qu'il ne faut aux déductions de pures hypothèses.""
"Le premier regard de l'homme jeté sur l'univers n'y découvre que variété, diversité, multiplicité des phénomènes. Que ce regard soit illuminé par la science, — par la science qui rapproche l'homme de Dieu, — et la simplicité et l'unité brillent de toutes parts."
"A bottle of wine contains more philosophy than all the books in the world."
"Let me tell you the secret that has led me to my goal. My strength lies solely in my tenacity."
"One does not ask of one who suffers: What is your country and what is your religion? One merely says: You suffer, that is enough for me..."
"Science knows no country, because knowledge belongs to humanity, and is the torch which illuminates the world. Science is the highest personification of the nation because that nation will remain the first which carries the furthest the works of thought and intelligence."
"Young men, have confidence in those powerful and safe methods, of which we do not yet know all the secrets. And, whatever your career may be, do not let yourselves become tainted by a deprecating and barren scepticism, do not let yourselves be discouraged by the sadness of certain hours which pass over nations. Live in the serene peace of laboratories and libraries. Say to yourselves first : "What have I done for my instruction?" and , as you gradually advance, "What have I done for my country?" until the time comes when you may have the immense happiness of thinking that you have contributed in some way to the progress and to the good of humanity. But, whether our efforts are or not favoured by life, let us be able to say, when we come near the great goal, "I have done what I could.""
"Posterity will one day laugh at the foolishness of modern materialistic philosophers. The more I study nature, the more I stand amazed at the work of the Creator. I pray while I am engaged at my work in the laboratory."
"I beseech you to take interest in these sacred domains so expressively called laboratories. Ask that there be more and that they be adorned for these are the temples of the future, wealth and well-being. It is here that humanity will grow, strengthen and improve. Here, humanity will learn to read progress and individual harmony in the works of nature, while humanity's own works are all too often those of barbarism, fanaticism and destruction."
"L' univers est dissymetrique..."
"There does not exist a category of science to which one can give the name applied science. There are sciences and the applications of science, bound together as the fruit of the tree which bears it."
"Dans les champs de l'observation le hasard ne favorise que les esprits préparés."
"I am on the edge of mysteries and the veil is getting thinner and thinner."
"I feel that the greatest reward for doing is the opportunity to do more."
"He felt that he couldn't ask other parents to let him give this vaccine to their children if he wasn't willing to first try it on his own."
"Young man, a great tragedy has befallen you. You have lost your anonymity."
"The work of Dr. Salk is in the highest tradition of selfless and dedicated medical research. He has provided a means for the control of a dread disease. By helping scientists in other countries with technical information; by offering to them the strains of seed virus and professional aid so that the production of vaccine can be started by them everywhere; by welcoming them to his laboratory that they may gain a fuller knowledge, Dr. Salk is a benefactor of mankind. His achievement, a credit to our entire scientific community, does honor to all the people of the United States."
"I speak about universal evolution and teleological evolution, because I think the process of evolution reflects the wisdom of nature. I see the need for wisdom to become operative. We need to try to put all of these things together in what I call an evolutionary philosophy of our time."
"I judge things from an evolutionary perspective — "How does this serve and contribute to the process of our own evolution?" — rather than think of good and evil in moral terms. I see the triumph of good over evil as a manifestation of the error-correcting process of evolution."
"I see weeds and flowers. I think of it in those terms, and we have to discriminate and distinguish between the two, to recognize and encourage those human qualities and attributes that are the more positive."
"My life is pretty well at peace, and the profession is more of an avocation. It's a calling, if you like, rather than a job. I do what I feel impelled to do, as an artist would. Scientists function in the same way. I see all these as creative activities, as all part of the process of discovery. Perhaps that's one of the characteristics of what I call the evolvers, any subset of the population who keep things moving in a positive, creative, constructive way, revealing the truth and beauty that exists in life and in nature."
"The idea of being constructive, creative, positive, in trying to bring out the best in one's own self and the best in others follows from what I've just been saying. Again, I repeat my belief in us, in ourselves, as the product of the process of evolution, and part of the process itself. I think of evolution as an error-making and error-correcting process, and we are constantly learning from experience. It's the need to dedicate one's self in that way, to one's own self, and to choose an activity or life that is of value not only to yourself but to others as well."
"Know what is the purpose of life that you are inclined to serve, that you are drawn to. Do what makes your heart leap rather than simply follow some style or fashion. Not everyone can or should be a scientist. Not everyone can or should be any one thing. People need to know what kind of purpose they can serve."
"The first thing I would like to point out is that each of us have a different purpose that we have to serve in the evolutionary scheme of things. We are not all equally endowed to do everything. When I speak about teleological evolution, I speak about the idea of "telos," purpose."
"What you see in living systems, and in genetic systems, is that the genes are already there, having arisen in the course of time, and when they are needed they become activated. If they had to be invented, the time would be too late. By the same token, I think that the people who are needed to help guide the future already exist. They simply need to recognize this in themselves, react to the opportunities that prevail, and also be valued and be encouraged. It's that very large, and as yet amorphous, rung that is of interest to me. I hope to articulate this, and see to what extent it makes sense to others as well."
"I am interested in a phase that I think we are entering. I call it "teleological evolution," evolution with a purpose. The idea of evolution by design, designing the future, anticipating the future. I think of the need for more wisdom in the world, to deal with the knowledge that we have. At one time we had wisdom, but little knowledge. Now we have a great deal of knowledge, but do we have enough wisdom to deal with that knowledge?"
"Reason alone will not serve. Intuition alone can be improved by reason, but reason alone without intuition can easily lead the wrong way. They both are necessary. The way I like to put it is that when I have an intuition about something, I send it over to the reason department. Then after I've checked it out in the reason department, I send it back to the intuition department to make sure that it's still all right. That's how my mind works, and that's how I work. That's why I think that there is both an art and a science to what we do. The art of science is as important as so-called technical science. You need both. It's this combination that must be recognized and acknowledged and valued."
"I have come to associate a kind of success that we are referring to, to individuals who have a combination of attributes that are often associated with creativity. In a way they are mutants, they are different from others. And they follow their own drummer. We know what that means. And are we all like that? We are not like that. If you are, then it would be well to recognize that there were others before you. And, people like that are not very happy or content, until they are allowed to express, or they can express what's in them to express. It's that driving force that I think is like the process of evolution working on us, and in us, and with us, and through us. That's how we continue on, and will improve our lot in life, solve the problems that arise. Partly out of necessity, partly out of this drive to improve."
"The evolvers are people who cause things to change. The maintainers of the status quo do everything to keep things from changing. And, there I see differences of perception. Differences in vision. Differences in interpretation, and differences in temperament, in personality. The number of evolvers are much fewer than the maintainers of the status quo. And amongst the evolvers, there are some who are initiators, some who go along with what other people recognize to be new or different."
"Since whatever we do has to be part of a team, part of a community, we have to attempt to bring together those who have the same conviction, see the same things. Then it becomes a matter of time, when one or the other will prevail. Fortunately, there is all this diversity, and if not for that, problems would not be solved."
"You can have a team of unconventional thinkers, as well as conventional thinkers. If you don't have the support of others you cannot achieve anything altogether on your own. It's like a cry in the wilderness. In each instance there were others who could see the same thing, and there were others who could not. It's an obvious difference we see in those who you might say have a bird's eye view, and those who have a worm's eye view. I've come to realize that we all have a different mind set, we all see things differently, and that's what the human condition is really all about."
"Now, some people might look at something and let it go by, because they don't recognize the pattern and the significance. It's the sensitivity to pattern recognition that seems to me to be of great importance. It's a matter of being able to find meaning, whether it's positive or negative, in whatever you encounter. It's like a journey. It's like finding the paths that will allow you to go forward, or that path that has a block that tells you to start over again or do something else."
"You have to develop a thick skin in life. Its not in this field only. You might think of the ideal of the scientists, the ivory tower, the idealist. That's true of some. And I wouldn't guess as to what proportion. But there are some who are of that character, and there are some who are not."
"There are three stages of truth. First is that it can't be true, and that's what they said. You couldn't immunize against polio with a killed-virus vaccine. Second phase: they say, "Well, if it's true, it's not very important. And the third stage is, 'Well, we've known it all along.""
"My attitude was always to keep open, to keep scanning. I think that's how things work in nature. Many people are close-minded, rigid, and that's not my inclination."
"Risks, I like to say, always pay off. You learn what to do, or what not to do."
"Why do I see things differently from the way other people see them? Why do I pursue the questions that I pursue, even if others regard them as, as they say, "controversial?" Which merely means that they have a difference of opinion. They see things differently. I am interested both in nature, and in the human side of nature, and how the two can be brought together, and effectively used."