"Do you know how many children die every year from choking on french fries? Many more than from Adrenoleukodystrophy. You see, ours is what is known as an orphan disease, too small to be noticed, too small to be funded, especially with the iron hand of "Reaganomics"."

"Susan Sarandon - Michaela Odone"

"Margo Martindale - Wendy Gimble"

"Ann Hearn - Loretta Muscatine"

"Kathleen Wilhoite - Deirdre Murphy"

"Zack O'Malley Greenburg - Lorenzo Odone"

"Peter Ustinov - Professor Nikolais"

"Nick Nolte - Augusto Odone"

"The question is, 'Do I have a 'God Complex'?...which makes me wonder if this lawyer has any idea as to the kind of grades one has to receive in college to be accepted at a top medical school. Or if you have the vaguest clue as to how talented someone has to be to lead a surgical team. I have an M.D. from Harvard, I am board certified in cardio-thoracic medicine and trauma surgery, I have been awarded citations from seven different medical boards in New England, and I am never, ever sick at sea. So I ask you; when someone goes into that chapel and they fall on their knees and they pray to God that their wife doesn't miscarry or that their daughter doesn't bleed to death or that their mother doesn't suffer acute neural trauma from postoperative shock, who do you think they're praying to? Now, go ahead and read your Bible, Dennis, and you go to your church, and, with any luck, you might win the annual raffle. But if you're looking for God, he was in operating room number two on November 17, and he doesn't like to be second guessed. You ask me if I have a God complex? Let me tell you something: I am God."

"Bad things happen to good people all the time, Andy, for no reason whatsoever."

"I'm the new guy around here and I want to make friends, so I'll say this to you and we'll start fresh. If you don't like my jokes, don't laugh. If you have a medical opinion, then please speak up and speak up loud. But if you ever again tell me or my surgical staff that we're going to lose a patient, I'm gonna take out your lungs with a fuckin' ice cream scoop. Do you understand me?"

"Ask God how many shots of bourbon he had before he cut me open."

"Tobin Bell – Earl Leemus"

"You want something done right, dammit, you call a teacher."

"George C. Scott – Dr. Martin Kessler"

"Josef Sommer – Lester Adams"

"Bill Pullman – Andy Safian"

"Debrah Farentino – Nurse Tanya"

"Alec Baldwin – Dr. Jed Hill"

"Nicole Kidman – Tracy Safian"

"Bebe Neuwirth – Dana Harris"

"Gwyneth Paltrow – Paula Bell"

"What the fuck do you think I want, Trace? I want half."

"Her doctor wasn't playing God. He thought he was God."

"Brenda Strong – Claudia, Riley's secretary"

"Deception. Betrayal. Murder. Some things you never see coming."

"Anne Bancroft – Mrs. Kennsinger"

"Peter Gallagher – Dennis Riley"

"Robert Desiderio - Dr. Banks"

"Zakes Mokae - Dr. Banumbra"

"Alice Carter - Kim McCauley"

"Todd Field - David Schreiner"

"Daphne Zuniga - Laurie Rorbach"

"Christine Lahti - Dr. Rachel Woodruff"

"John Scott Clough - Miles Reed"

"[to his family after reading a letter from a med school] What? What's the matter? You never seen a medical student before?"

"[confronting Dr. Woodruff after his roommate was asked to leave medical school] He's human. Not superhuman, just human. He did what he thought he had to do because he wanted to be a doctor more than anything else in the world and you ruined this for him."

"And now, now I just wonder about some of these brilliant doctors of mine. You know, with their minds for medicine and their hearts for, what, real estate. You know, I wonder what they'd say to some lonely terrified patient, who grabs their hand and says, "Can you explain this to me? Can you help me accept this? Can you at least sit with me so I don't feel so alone?" Well, I bet they don't say anything because I didn't teach them to."

"No one thought a rebel like Joe Slovak would make it through Medical School. But they didn't know Joe."

"It Takes Hard Work, Discipline, And Committment To Get Through Med School. But Joe's Never Done Anything By The Book."

"Matthew Modine - Joe Slovak"

"He was a doctor who thought he knew it all... until he became a patient."

"If I ever hear you describe a patient as "terminal" again, that's how you'll describe your career!"

"[to Dr. MacKee] I am the doctor and you are the patient and I am telling you when I am available."

"An Uplifting Story About Finding New Meaning In Life."

"I've always wanted to slit your throat, and now I get a chance to."