Chemistry

"The ego becomes more like the inner ego and less like its old self, comparatively speaking. It accepts large portions of reality that it previously denied. Structurally, it remains intact, yet it has changed chemically and electromagnetically. Now it is far more open to inner data. Once this freedom is achieved, the ego can never return to its old state."

"Be a physical chemist, an analytical chemist, an organic chemist, if you will; but above all, be a chemist"

"The recognition of certain basic impossibilities has laid the foundations of some major principles of physics and chemistry; similarly, recognition of the impossibility of understanding living things in terms of physics and chemistry, far from setting limits to our understanding of life, will guide it in the right direction. And even if the demonstration of this impossibility should prove of no great advantage in the pursuit of discovery, such a demonstration would help to draw a truer image of life and man than that given us by the present basic concepts of biology."

"It has never been in my power to study anything, — mathematics, ethics, metaphysics, gravitation, thermodynamics, optics, chemistry, comparative anatomy, astronomy, psychology, phonetics, economics, the history of science, whist, men and women, wine, metrology, except as a study of semeiotic."

"The Second Law of Thermodynamics states that all energy systems run down like a clock and never rewind themselves. But life not only 'runs up,' converting low energy sea-water, sunlight and air into high-energy chemicals, it keeps multiplying itself into more and better clocks that keep 'running up' faster and faster. Why, for example, should a group of simple, stable compounds of carbon, hydrogen, oxygen and nitrogen struggle for billions of years to organize themselves into a professor of chemistry? What's the motive? If we leave a chemistry professor out on a rock in the sun long enough the forces of nature will convert him into simple compounds of carbon, oxygen, hydrogen and nitrogen, calcium, phosphorus, and small amounts of other minerals. It's a one-way reaction. No matter what kind of chemistry professor we use and no matter what process we use we can't turn these compounds back into a chemistry professor. Chemistry professors are unstable mixtures of predominantly unstable compounds which, in the exclusive presence of the sun's heat, decay irreversibly into simpler organic and inorganic compounds. That's a scientific fact. The question is: Then why does nature reverse this process? What on earth causes the inorganic compounds to go the other way? It isn't the sun's energy. We just saw what the sun's energy did. It has to be something else. What is it?"

"Just think of the differences today. A young person gets interested in chemistry and is given a chemical set. But it doesn't contain potassium cyanide. It doesn't even contain copper sulfate or anything else interesting because all the interesting chemicals are considered dangerous substances. Therefore, these budding young chemists don't get a chance to do anything engrossing with their chemistry sets. As I look back, I think it is pretty remarkable that Mr. Ziegler, this friend of the family, would have so easily turned over one-third of an ounce of potassium cyanide to me, an eleven-year-old boy."

"We may, I believe, anticipate that the chemist of the future who is interested in the structure of proteins, nucleic acids, polysaccharides, and other complex substances with high molecular weight will come to rely upon a new structural chemistry, involving precise geometrical relationships among the atoms in the molecules and the rigorous application of the new structural principles, and that great progress will be made, through this technique, in the attack, by chemical methods, on the problems of biology and medicine."

"Every chemical substance, whether natural or artificial, falls into one of two major categories, according to the spatial characteristic of its form. The distinction is between those substances that have a plane of symmetry and those that do not. The former belong to the mineral, the latter to the living world."

"There is a narrowness of action, though not of intent, which characterizes university departments, and scientific publications and scientists in general: if it is too popular, it is somehow vulgar and wrong. You can't really speak to those people across the street. I live next to the chemists at MIT, but I never see them. I hardly know who they are, yet between physics and chemistry it is hard to know who should study what molecule. I myself am guilty. We form communities not based on the problems of science, but on quite other things. This is part of the general split between the intelligent member of the public and the scientist who speaks in narrow focus. But the great theoretical problems which I believe the world expects will somehow be solved by science, problems close to deep philosophical issues are the very problems that find the least expertise, the least degree of organization, the least institutional support in the scientific institutions of America or indeed of the world."

"Chemistry without catalysis would be a sword without a handle, a light without brilliance, a bell without sound."

"But we are still blind... blind and we don't have those tweezers we often dream of at night, the way a thirsty man dreams of springs, that would allow us to pick up a segment, hold it firm and straight, and paste it in the right direction on the segment that has already been assembled. If we had those tweezers (and it's possible that, one day, we will), we would have managed to create some wonderful things But for the present we don't have those tweezers, and when we come right down to it, we're bad riggers."

"I could tell innumerable other stories and they would all be true: all literally true, in the nature of the transitions, in their order and data. The number of atoms is so great that one could always be found whose story coincides with any capriciously invented story."

"Having reached this point in life, what chemist, facing the Periodic Table or the monumental indices of Beilstein or Landolt, does not perceive scattered amoung them the sad tatters, or trophies, of his own professional past? He only has to leaf through any treatise and memories rise up in bunches: there is among us he who has tied his destiny, indelibly, to bromine or to propylene, or the -NCO group, or glutamic acid; and every chemistry student, faced by almost any treatise, should be aware that on one of those pages, perhaps in a single line, formula, or word, his future is written in indecipherable characters, which, however, will become clear "afterward": after success, error, or guilt, victory or defeat. Every no longer young chemist, turning again to the verhängnis voll page in that same treatise, is struck by love or disgust, delights or despairs."

"That conquering matter is to understand it, and understanding matter is necessary to understanding the universe and ourselves: and that therefore Mendeleev's Periodic Table, which just during those weeks we were laboriously learning to unravel, was poetry, loftier and more solemn than all the poetry we had swallowed down in liceo; and come to think of it, it even rhymed!"

"For me chemistry represented an indefinite cloud of future potentialities which enveloped my life to come in black volutes torn by fiery flashes, like those which had hidden Mount Sinai. Like Moses, from that cloud I expected my law, the principle of order in me, around me, and in the world. I was fed up with books, which I still continued to gulp down with indiscreet voracity, and searched for a key to the highest truths; there must be a key, and I was certain that, owing to some monstrous conspiracy to my detriment and the world's, I would not get in school. In school they loaded with me with tons of notions that I diligently digested, but which did not warm the blood in my veins. I would watch the buds swell in spring, the mica glint in the granite, my own hands, and I would say to myself: "I will understand this, too, I will understand everything, but not the way they want me to. I will find a shortcut, I will make a lock-pick, I will push open the doors." It was enervating, nauseating, to listen to lectures on the problem of being and knowing, when everything around us was a mystery pressing to be revealed: the old wood of the benches, the sun's sphere beyond the windowpanes and the roofs, the vain flight of the pappus down in the June air. Would all the philosophers and all the armies of the world be able to construct this little fly? No, nor even understand it: this was a shame and an abomination, another road must be found."

"Somehow, the practice of astronomy, physics, chemistry or biology normally fails to evoke the controversies over fundamentals that today seem endemic among, say, psychologists or sociologists. Attempting to discover the source of that difference led me to recognize the role in scientific research of what I have since called “paradigms.” These I take to be universally recognized scientific achievements that for a time provide model problems and solutions for a community of practitioners."

"The Joker: You IDIOT! You made me. Remember? You dropped me into that vat of chemicals. That wasn't easy to get over, and don't think that I didn't try."

"The natural sciences are sometimes said to have no concern with values, nor to seek morality and goodness, and therefore belong to an inferior order of things. Counter-claims are made that they are the only living and dynamic studies. Both contentions are wrong"

"Modern warfare, we discovered, was to a far greater extent than ever before a conflict of chemists and manufacturers. Manpower, it is true, was indispensable, and generalship will always, whatever the conditions, have a vital part to play. But troops, however brave and well led, were powerless under modern conditions unless equipped with adequate and up-to-date artillery (with masses of explosive shell), machine-guns, aircraft and other supplies. Against enemy machine-gun posts and wire entanglements the most gallant and best-led men could only throw away their precious lives in successive waves of heroic martyrdom. Their costly sacrifice could avail nothing for the winning of victory."

"The underlying physical laws necessary for the mathematical theory of a large part of physics and the whole of chemistry are thus completely known, and the difficulty is only that the exact application of these laws leads to equations much too complicated to be soluble. It therefore becomes desirable that approximate practical methods of applying quantum mechanics should be developed, which can lead to an explanation of the main features of complex atomic systems without too much computation."

"The chemists are a strange class of mortals, impelled by an almost insane impulse to seek their pleasures amid smoke and vapour, soot and flame, poisons and poverty; yet among all these evils I seem to live so sweetly that may I die if I were to change places with the Persian king."

"Within a certain kind of environment, an activity may be checked so that the only meaning which accrues is of its direct and tangible isolated outcome. One may cook, or hammer, or walk, and the resulting consequences may not take the mind any farther than the consequences of cooking, hammering, and walking in the literal — or physical — sense. But nevertheless the consequences of the act remain far-reaching. To walk involves a displacement and reaction of the resisting earth, whose thrill is felt wherever there is matter. It involves the structure of the limbs and the nervous system; the principles of mechanics. To cook is to utilize heat and moisture to change the chemical relations of food materials; it has a bearing upon the assimilation of food and the growth of the body. The utmost that the most learned men of science know in physics, chemistry, physiology is not enough to make all these consequences and connections perceptible. The task of education, once more, is to see to it that such activities are performed in such ways and under such conditions as render these conditions as perceptible as possible."

"At some point a particularly remarkable molecule was formed by accident. We will call it the Replicator. It may not necessarily have been the biggest or the most complex molecule around, but it had the extraordinary property of being able to create copies of itself."

"We must not forget that when radium was discovered no one knew that it would prove useful in hospitals. The work was one of pure science. And this is a proof that scientific work must not be considered from the point of view of the direct usefulness of it. It must be done for itself, for the beauty of science, and then there is always the chance that a scientific discovery may become like the radium a benefit for humanity."

"The nature of the chemical bond is the problem at the heart of all chemistry."

"On the arid lands there will spring up industrial colonies without smoke and without smokestacks; forests of glass tubes will extend over the plains and glass buildings will rise everywhere; inside of these will take place the photochemical processes that hitherto have been the guarded secret of the plants, but that will have been mastered by human industry which will know how to make them bear even more abundant fruit than nature, for nature is not in a hurry and mankind is. And if in a distant future the supply of coal becomes completely exhausted, civilization will not be checked by that, for life and civilization will continue as long as the sun shines!"

"Here, for the first time, we find ourselves a little at issue with the accepted system of chemistry. Fluorine stands at the head of a group—called the inter-periodic—whereof the remaining members are (see Crookes' table, p. 28), manganese, iron, cobalt, nickel; ruthenium, rhodium, palladium; osmium, iridium, platinum. If we take all these as group V, we find that fluorine and manganese are violently forced into company with which they have hardly any points of relationship, and that they intrude into an otherwise very harmonious group of closely similar composition. (Chapter III. The Later Researches, part V.—The Bars Groups)"

"The first difficulty that faced us was the identification of the forms seen on focusing the sight on gases. We could only proceed tentatively. Thus, a very common form in the air had a sort of dumb-bell shape (see Plate I); we examined this, comparing our rough sketches, and counted its atoms; these, divided by 18—the number of ultimate atoms in hydrogen—gave us 23.22 as atomic weight, and this offered the presumption that it was sodium. We then took various substances—common salt, etc.—in which we knew sodium was present, and found the dumb-bell form in all. In other cases, we took small fragments of metals, as iron, tin, zinc, silver, gold; in others, again, pieces of ore, mineral waters, etc., etc.... In all, 57 chemical elements were examined, out of the 78 recognized by modern chemistry. In addition to these, we found 3 chemical waifs: an unrecognized stranger between hydrogen and helium which we named occultum, for purposes of reference, and 2 varieties of one element, which we named kalon and meta-kalon, between xenon and osmium... Thus we have tabulated in all 65 chemical elements, or chemical atoms, completing three of Sir William Crookes' lemniscates, sufficient for some amount of generalization. (Chapter III. The Later Researches)"

"The important point is not the bigness of Avogadro's number but the bigness of Avogadro."

"It was a great achievement of the early chemists — with the crude experimental techniques available also with the ever-astonishing power of human reason (as potent then as now) — to discover this reduction of the world to its components, the chemical elements. Such reduction does not destroy its charm but adds understanding to sensation, and this understanding only deepens our delight."

"Never before has mankind had to face the possibility of extinction in all-out fusion bomb war, nor has it had occasion for hope of unexampled prosperity in the taming of that same fusion bomb. Either fate could result from a single branch of scientific advance. We are gaining the knowledge; science is giving us that. Now we need wisdom as well."

"At this time organic chemistry can drive one completely crazy. It seems to me like a primeval tropical jungle, full of the most remarkable things, an amazing thicket, without escape or end, into which one would not dare to enter."

"Cellular pathology is not an end if one cannot see any alteration in the cell. Chemistry brings the clarification of living processes nearer than does anatomy. Each anatomical change must have been preceded by a chemical one."

"Chemistry, unlike other sciences, sprang originally from delusions and superstitions, and was at its commencement exactly on a par with magic and astrology."

"In the four quarters of the globe, who reads an American book? Or goes to an American play? or looks at an American picture or statue? What does the world yet owe to American physicians or surgeons? What new substances have their chemists discovered? Or what old ones have they advanced? What new constellations have been discovered by the telescopes of Americans? Who drinks out of American glasses? Or eats from American plates? Or wears American coats or gowns? or sleeps in American blankets? Finally, under which of the old tyrannical governments of Europe is every sixth man a slave, whom his fellow-creatures may buy and sell and torture?"

"'I am happy', said M. Waldman, 'to have gained a disciple; and if your application equals your ability, I have no doubt of your success. Chemistry is that branch of natural philosophy in which the greatest improvements have been and may be made: it is on that account that I have made it my peculiar study'"

"Do you believe then that the sciences would ever have arisen and become great if there had not beforehand been magicians, alchemists, astrologers, and wizards who thirsted and hungered after... forbidden powers?"

"As Mechanical Philosophy has a respect to those motions of the larger bodies of the universe which fall under the inspection of our senses, so Chemical Philosophy is the science which explains those motions which take place among the minute component parts of bodies, and which are known chiefly by the effects which they produce; in other words, its object is, "to ascertain the ingredients that enter into the composition of bodies—to examine the nature of these ingredients, the manner in which, and the laws by which, they combine, and the properties resulting from their combination." It may safely be asserted, that there is no branch of science in which the discoveries and improvements, during the last century, have been more numerous, or more important, than in this. Indeed, such has been their number, and their interesting nature, that to exhibit them in detail would be to fill volumes."

"I wish to establish some sort of system not guided by chance but by some sort of definite and exact principle."

"Chemistry, in its application to animals and vegetables. Endeavours jointly with physiology to enlighten us respecting the mysterious processes and sources of organic life."

"The most powerful influence exercised by the Arabs on general natural physics was that directed to the advances of chemistry; a science for which this race created a new era.(...) Besides making laudatory mention of that which we owe to the natural science of the Arabs in both the terrestrial and celestial spheres, we must likewise allude to their contributions in separate paths of intellectual development to the general mass of mathematical science."

"It is a mistake to confound Alchemy with Chemistry. Modern Chemistry is a science which deals merely with the external forms in which the element of matter is manifesting itself. It never produces anything new. We may mix and compound and decompose two or more chemical bodies an unlimited number of times, and cause them to appear under various different forms, but at the end we will have no augmentation of substance, nor anything more than the combinations of the substances that have been employed at the beginning. Alchemy does not mix or compound anything, it causes that which already exists in a latent state to become active and grow. Alchemy is, therefore, more comparable to botany or agriculture than to Chemistry; and, in fact, the growth of a plant, a tree, or an animal is an alchemical process going on in the alchemical laboratory of nature, and performed by the great Alchemist, the power of God acting in nature."

"Once you are there you'll be like a drop of water in a piece of rock crystal- your medium will dignify your commonness."

"We can no more have exact religious thinking without theology, than exact mensuration and astronomy without mathematics, or exact iron-making without chemistry,"

"Reader! Imagine a school-boy who has outgrown his clothes. Imagine the repairs made on the vestments where the enlarged frame had burst the narrow limits of its inclosure. Imagine the additions made where the projecting limbs had fairly and far emerged beyond the confines of the garment. Imagine the boy still growing, and the clothes, mended all over, now more than ever in want of mending — such is chemistry, and such its nomenclature."

"Chemistry, Madame Lefrancois....the composition of manures, the fermentation of liquids, the analysis of gases and the influence of miasmata- what, I put it to you, is all this, but chemistry pure and simple?"

"One of the most immediate consequences of the electrochemical theory is the necessity of regarding all chemical compounds as binary substances. It is necessary to discover in each of them the positive and negative constituents... No view was ever more fitted to retard the progress of organic chemistry. Where the theory of substitution and the theory of types assume similar molecules, in which some of the elements can be replaced by others without the edifice becoming modified either in form or outward behaviour, the electrochemical theory divides these same molecules, simply and solely, it may be said, in order to find in them two opposite groups, which it then supposes to be combined with each other in virtue of their mutual electrical activity... I have tried to show that in organic chemistry there exist types which are capable, without destruction, of undergoing the most singular transformations according to the nature of the elements."

"It's chemistry, brother, chemistry! There's no help for it, your reverence, you must make way for chemistry."

"Most of the substances belonging to our globe are constantly undergoing alterations in sensible quantities, and one variety of matter becomes, as it were, transmuted into another. Such changes, whether natural or artificial, whether slowly or rapidly performed, are called chemical; thus the gradual and almost imperceptible decay of the leaves and branches of a fallen tree exposed to the atmosphere, and the rapid combustion of wood in our fires, are both chemical operations. The object of chemical philosophy is to ascertain the causes of all phenomena of this kind, and to discover the laws by which they are governed. The ends of this branch of knowledge are the applications of natural substances to new uses, for increasing the comforts and enjoyments of man, and the demonstration of the order, harmony, and intelligent design of the system of the earth."

"Chemical analysis and synthesis go no farther than to the separation of particles one from another, and to their reunion. No new creation or destruction of matter is within the reach of chemical agency. We might as well attempt to introduce a new planet into the solar system, or to annihilate one already in existence, as to create or destroy a particle of hydrogen.""