"[filling up a bag with stakes] How many more of these will I have to make before they're all destroyed? They want my blood. It's their lives or mine. I still get squeamish."

"I can't afford the luxury of anger. Anger can make me vulnerable. It can destroy my reason and reason's the only advantage I have over them."

"A dying world. An empty, dead, silent world."

"There was a time that eating was pleasurable. Now it bores me."

"December 1965. Is that all it has been since I inherited the world? Only three years. Seems like a hundred million."

"Another day to live through. Better get started."

"Army officer: [during Neville's flashback to the military conflict] Abort firing! Abort firing! Interception will fragment bacilli carrying missile! Abort firing! Abort firing!"

"Lisa: Is there anything you can do, DOCTOR, I mean, seeing as how you've lost over 200 million patients?"

"Here is the instrument of cleansing, my brethren. And nothing quite cleanses like fire."

"Take him to the little room... for questioning."

"We were warned about The End. Well, here it is."

"[Unsure whether or not he saw a healthy human woman or if it just his imagination] Is this how it starts? A trip to the laughing academy? No, you silly bastard, it starts with you asking yourself silly questions. Okay, let's get cleaned up."

"And Speedy Bob Neville- his great legs churning goes speeding across the finish line with a three minute and fifty second mile. Go ahead, let's see some son-of-a-bitch beat that."

"You know the old song? If you were the only girl in the world, and I was the only boy, well, okay, but until then, don't bother me? Well, I guess I'm the only boy...."

"[hearing the "Family" loudly holding a book-burning revel] At it again, I see? What will it be tonight? Museum of Science? Some library? Poor miserable bastards."

"[talking to his own image on a TV screen] Hi, Big Brother, how's your ass?"

"[Enters a car dealership in search of a new car, talks to a decomposed corpse of a car salesman] Cannot say I am too crazy about the paint job...Thanks a lot you cheating bastard."

"[first lines, as the last man on earth wrecks his car] There's never a cop around when you need one."

"[later, to the bust of Caesar] What day is it, anyway? Monday? Huh? The hell it is. It's Sunday. Sunday I always dress for dinner."

"[to the "Family"] SHUT UP! Why the hell can't you leave me alone?"

"Isn't he? Isn't he a sullen b- [stops when he hears the "Family" outside]"

"[makes drink] Join me? Hmm? Miserable schmuck! [to his own image on the video screen]"

"[To a bust of Julius Caesar set up near a chessboard] Your move, Imperator."