"The probability of containment is diminishing daily. It's really unfortunate because we do have the tools. This is not an unknown virus. … We have vaccines that are already available, even vaccines with indications for monkeypox. Therapeutics. And we know what's needed to be done."

"Right now we just don't have nearly enough vaccine to even begin to have a measurable impact on widespread global transmission. There's going to be a lot of frustrated people who want to get vaccine where it won't be available."

"Declaring a PHEIC makes governments and the global public sit up and take notice. It raises the political stakes for government leaders, and it raises the level of accountability for them to act."

"Public health officials reject comparisons to the early days of the coronavirus pandemic, when they mandated masks and shut down public spaces. They noted that the novel coronavirus was unfamiliar, far deadlier and airborne, with hospitals overrun with patients at various points over the past two years. Monkeypox has known treatments and vaccines, although they have been challenging to access; it also has not killed anyone in the United States, and hospitalizations are uncommon."

"We are prepared to take our response to the next level in addressing this virus and we urge every American to take monkeypox seriously."