"[To Watson, about him incorrectly pronouncing Blackwood dead] This is a matter of professional integrity. No girl wants to marry a doctor who can't even tell if a man's dead or not."

"The game is afoot. [In unison with Watson] Follow your spirit and upon this charge – Cry, God for Harry, England and Saint George!"

"[First lines; surveying a ruffian guard; voiceover] Head cocked to the left. Partial deafness in ear. [Holmes slaps the guard in the left ear] First point of attack. Two: throat; paralyse vocal chords, stop scream. [Grabs the guard by the neck, stifling his vocal cords and silencing his scream] Three: got to be heavy drinker. Floating rib to the liver. [The guard gets punched in the gut] Four: finally, drag in left leg, fist to patella. [Punches and drags the left leg] Summary prognosis: conscious in ninety seconds, partial efficacy: quarter of an hour at best. Full faculty recovery: unlikely. [Back in real time, Holmes uses his coat to conceal himself in the shadows, and as the guard strolls past him, Holmes leaps out, does all of the above in a matter of seconds, and steals the guard's bowler hat and lantern, before taking off down the stairs.]"

"[To Irene] I was simply studying your methods … should the authorities ask me to hunt you down."

"Hans Matheson – Lord Coward"

"James Fox – Sir Thomas"

"Geraldine James – Mrs. Hudson"

"Mark Strong – Lord Blackwood"

"Eddie Marsan – Inspector Lestrade"

"Kelly Reilly – Mary Morstan"

"Downey's Holmes is at once more dissolute and more fit than previous incarnations. Holmes' canonical devotion to cocaine is here augmented by other drugs and a great deal of booze. Yet Holmes has the body of a lithe athlete, the skills of a gymnast and the pugilism of a world champion. He and Watson (who is, you recall, only a doctor, although one with clients who must be puzzled about his office hours) spring readily into action like Batman and Robin. … The Conan Doyle stories are still read, and probably always will be. Most readers get to at least a few. But among moviegoers on Christmas night (traditionally one of the busiest movie nights of the year), probably not so many. They will be unaware that this "Sherlock Holmes" is cheerfully revisionist. They will be entertained, and so was I. The great detective, who has survived so much, can certainly shrug off a few special effects."

"Nothing Escapes Him"

"Holmes: Nothing more elusive than an obvious fact."

"Jude Law – Dr. John Watson"

"Holmes: My mind rebels at stagnation; give me problems, give me work."

"Rachel McAdams – Irene Adler"

"Mary Morstan: He'd say it was worth the wound … I know you care about him as much as I do."

"Holmes: The little details are by far the most important."

"Holmes: Data, data, data, I cannot make bricks without clay."

"Watson: You're not human!"

"Holmes: It is a capital mistake to theorize before one has data. Inevitably, one begins to twist facts to suit theories, instead of theories to suit facts."

"Mary Morstan: [to Holmes] Solve this … whatever it takes."

"Professor Moriarty: [to Adler, aboard a train] The train will depart when I tell it to. And you will leave my employment when I allow you to."

"Holmes: Crime is common. Logic is rare."

"Holmes: You have the grand gift of silence, Watson. It makes you quite invaluable as a companion."

"Mrs. Hudson: Oh, he's killed the dog … again."

"Cemetery Groundskeeper: I know what I saw! It was Blackwood. As clearly as I see you. And when the dead walk … the living will fill these coffins."

"[Holmes is reeling from the doctored wine she gave him] I told you to let it breathe. Can you taste the comet?"

"Tanner: Oh, you've found a sense of humor, Doctor! … If only just a sense."

"Lord Coward: How terrible is wisdom, when it brings no profit to the wise."

"Holmes: It makes a considerable difference to me, having someone with me on whom I can thoroughly rely."

"Ah … putrefaction."

"Even in Britain, Crime is Crime."

"What else you gonna do on a Saturday?"

"500,000 single women in London and I still can't get me fakin end away cause I'm a fakin stumblebum."

"Danny Dyer - Tommy Johnson"

"Getting beaten up by football hooligans is like having V.D. The fucking pain goes on forever. But that's what makes it so exciting."

"My granddad, old Bill Farrell, drove us to drink with his stories about the war and how he fought to put the "Great" into Britain. He said fighting at football was nothing compared to fighting with the Germans... Although, he was right. We're an island race. It's what we do best. It's not about color or race, it's just the buzz of being in the frontline. Truth is, I just love to fight."

"Frank Harper - Billy Bright"

"The next best thing to violence is sex. And seeing as there's nearly 500,000 single women in London, I must be in with half a chance. Especially as I'd fuck anything that's breathing."

"There's nothing different about me. I'm just another bored male, approaching 30, in a dead-end job. Casual sex, heavily cut drugs and occasionally kicking fuck out of someone."

"What else are you gonna do on a Saturday? Sit in your fuckin' armchair wankin' off to Pop Idols? Then try and avoid your wife's gaze as you struggle to come to terms with your sexless marriage? Then go and spunk your wages on kebabs, fruit machines and brasses? Fuck that for a laugh! I know what I'd rather do. Tottenham away, love it!"

"Jesus! I was expecting a bowl of cornflakes and a quick wank..."

"Problem was, he'd taken so many beatings on the terraces that he weren't scared of anyone. And the correct medical term for that is a "total fuckin' psycho"."

"What else you gonna do on a Saturday? Sit in ya fucking armchair wanking off to Pop Idols? then try and avoid your wife's gaze struggle to come to terms with your sexless marriage? Then go and spunk your wages on kebabs, fruit machines and brasses? I know what I'd rather do. Tottenham away. Love it!"

"I'm gonna smash the fuckin' granny out of that."

"Neil Maskell - Rod"