All Quotes

"N.B. This is rote sarcastikul."

"The female woman is one of the greatest institooshuns of which this land can boste."

"Yes; there was an oration. We have a passion for oratory in America—political oratory chiefly. Our political orators never lose a chance to "express their views." They will do it. You cannot stop them.There was an execution in Ohio one day, and the Sheriff, before placing the rope round the murderer's neck, asked him if he had any remarks to make?"If he hasn't," said a well-known local orator, pushing his way rapidly through the dense crowd to the gallows—"if our ill-starred feller-citizen don't feel inclined to make a speech and is in no hurry, I should like to avail myself of the present occasion to make some remarks on the necessity of a new protective tariff!""

"Drugs are tearing apart our societies, spawning crime, spreading diseases such as AIDS, and killing our youth and our future."

"In the first chapter, Thompson famously describes the stash he’s accumulated for his weekend road trip to Vegas: “two bags of grass, seventy-five pellets of mescaline, five sheets of high-powered blotter acid, a saltshaker half-full of cocaine, and a whole galaxy of uppers, downers, laughers, screamers.” This is in addition to “a quart of tequila, a quart of rum, a case of beer, a pint of raw ether, and two dozen amyls.” I resolved to try it all, down to the ether, which I finally located midway through tenth grade in a head shop on the West Side of Manhattan. (It gave me double vision and a headache.) Tracking down and taking everything on Thompson’s list became a kind of mission, a pharmacological scavenger hunt that preoccupied me through high school. At this point, I should add the customary disclaimer about how drugs are bad, a lie and a trap and a destroyer of lives. That’s all true, but not in my case. For me, the whole experience was interesting and fun. I had a great time. On the other hand, I grew out of it. By the time I got to college, mind expansion had lost its appeal. I switched to beer."

"A lot of people recoil from the word "drugs" - which is understandable given today's noxious street drugs and their uninspiring medical counterparts. Yet even academics and intellectuals in our society typically take the prototypical dumb drug, ethyl alcohol. If it's socially acceptable to take a drug that makes you temporarily happy and stupid, then why not rationally design drugs to make people perpetually happier and smarter? Presumably, in order to limit abuse-potential, one would want any ideal pleasure drug to be akin - in one limited but important sense - to nicotine, where the smoker's brain finely calibrates its optimal level: there is no uncontrolled dose-escalation."

"If you look into the history of what is called the CIA, which means the US White House, its secret wars, clandestine warfare, the trail of drug production just follows. It started in France after the Second World War when the United States was essentially trying to reinstitute the traditional social order, to rehabilitate Fascist collaborators, wipe out the Resistance and destroy the unions and so on. The first thing they did was reconstitute the Mafia, as strikebreakers or for other such useful services. And the Mafia doesn't do it for fun, so there was a tradeoff: Essentially, they allowed them to reinstitute the heroin production system, which had been destroyed by the Fascists. The Fascists tended to run a pretty tight ship; they didn't want any competition, so they wiped out the Mafia. But the US reconstituted it, first in southern Italy, and then in southern France with the Corsican Mafia. That's where the famous French Connection comes from. That was the main heroin center for many years. Then US terrorist activities shifted over to Southeast Asia. If you want to carry out terrorist activities, you need local people to do it for you, and you also need secret money to pay for it, clandestine hidden money. Well, if you need to hire thugs and murderers with secret money, there aren't many options. One of them is the drug connection. The so-called Golden Triangle around Burma, Laos and Thailand became a big drug producing area with the help of the United States, as part of the secret wars against those populations."

"People with mood disorders, including those who are unresponsive to conventional therapies, might be able to ditch their antidepressants and antianxiety medications. Those with terminal illness could enjoy their remaining days without the fear of death looming over them, while people with PTSD could return to a normal life unobstructed by paralyzing flashbacks. And rehab centers for substance use and eating disorders could empty out as more people turn to psychedelics."

"Philosophically, I think that if somebody wants to sit around and get stoned that's up to him or her. And if that ruins your life, so be it.... So I am for drug legalization."

"Dope is death! We must fight dope addiction by any means necessary! Do all you can to help your people in the anti-dope war!"

"[The committee] indicated directions in which to move with respect to policies of prevention, treatment, harm reduction and social reinsertion. One of our premises is that drug abusers are ill, not criminals, and that they need help,"

"...in my cohort we were slightly anti-hedonistic...it made it very much easier for police provocation to occur, because the planting of drugs was something that happened to almost everyone one knew."

"In a paper published this summer, Dr. Rafael dos Santos from the University of São Paulo in Brazil, along with his colleagues, sought to analyze and compile the research done on these drugs. Given the legal restrictions still placed on them, one difficulty in this area of research is identifying clinical trials conducted with the proper experimental methods and controls. Thus, of the 144 studies that the researcher found, only 6 made the cut for their analyses. Despite their small number, these studies reported consistent positive effects among their participants. For instance, psilocybin was found to improve symptoms of obsessive-compulsive disorder (OCD), reduce symptoms of anxiety and depression among terminally ill cancer patients, and decrease both alcohol and tobacco dependence among addicts. Likewise, LSD was reported to decrease anxiety symptoms associated with life-threatening diseases as well as help in the treatment of alcoholism. Crucially, the reported improvements lasted over the course of several days and, in some cases, months."

"If we could sniff or swallow something that would, for five or six hours each day, abolish our solitude as individuals, atone us with our fellows in a glowing exaltation of affection and make life in all its aspects seem not only worth living, but divinely beautiful and significant, and if this heavenly, world-transfiguring drug were of such a kind that we could wake up next morning with a clear head and an undamaged constitution—then, it seems to me, all our problems (and not merely the one small problem of discovering a novel pleasure) would be wholly solved and earth would become paradise."

"Rational and kindly behavior tends to produce good results and these results remain good even when the behavior which produced them was itself produced by a pill."

"Addictions come from shortages in infancy. People try to compensate this way. Alcoholism is generally produced from a shortage in mother's milk. And heroin addiction is usually due to a lack of being, the absence of recognition; the drug fills the emptiness of not being loved."

"Drug abuse and illicit trafficking in drugs are amongst the greatest threats to mankind today. When abused, narcotic drugs and psychotropic substances become a force of evil and destroy the lives of thousands of individuals and jeopardise the security and stability of nations. Drug addiction and illicit trafficking continue to spread worldwide and almost every country in the world suffers a broad range of tragic consequences from drug abuse. It is imperative that we take prompt and decisive actions to eliminate drug abuse and illicit trafficking from within our midst. For the campaign to be really successful it will require global action and the cooperation of all countries to coordinate a comprehensive strategy to eliminate this deadly menace. All countries will have to close rank and work together. The war against drugs has to be a total war. Many countries have come to realise this as borne by their presence at the International Conference on Drug Abuse and Illicit Trafficking (ICDAIT) held in Vienna last June. ICDAIT has brought together 138 nations and 173 specialised agencies and non-governmental organisations, determined to commit themselves to reducing and eventually eradicating drug abuse and illicit trafficking. ICDAIT agreed that vigorous and cohesive action by all governments and international organisations was required on all fronts to attain this goal. The Declaration adopted by the Conference is a clear expression of our collective political will and commitment to respond to the drug menace. It underlines a shared responsibility to provide appropriate response and resources to combat drug abuse and illicit trafficking. This Declaration also provides strong encouragement to all countries to reinforce and give priority to the anti-drug drive. Subsequent to ICDAIT, I am happy to note that many countries are becoming more serious in their efforts to reduce the production, supply of and demand for drugs and to curb illicit trafficking, both at national and international levels."

"I've had a lot of fun on drugs ... I've had a lot of marvellous experiences. I've danced a lot. I've had a great time. I'm not ashamed of it. And I don't see what's wrong with it."

"Three reports have surfaced in the literature of individuals with long-standing OCD who experienced significant alleviation of their disorder after what was initially a “recreational” use of LSD, peyote, or Psilocybe mushrooms. The most recent of these relates that a 34-year-old man who had suffered from OCD since the age of 6 found that both peyote and Psilocybe mushrooms moderated his symptoms (which included incapacitating and compulsive counting, showering, and ritualistic washing of his clothes, hands, and body). He began a 4-year course of daily Psilocybemushroom ingestion, which resulted in improvement of his OCD symptoms, unaccompanied by any hallucinogenic effects because of his acquired tolerance. During a subsequent 2-year period, his OCD remained in control without the need for him to ingest Psilocybe, but then the symptoms gradually returned to their initial levels. Some beginnings have been made in studying the effects of psychedelic drugs for alleviating OCD. The potential benefits of these drugs in anorexia nervosa, a devastating and not infrequently life-threatening disorder with few or no fully successful treatment options, should likewise be studied."

"To date, pharmacological treatments for mood and anxiety disorders and for drug dependence show limited efficacy, leaving a large number of patients suffering severe and persistent symptoms. Preliminary studies in animals and humans suggest that ayahuasca, psilocybin and lysergic acid diethylamide (LSD) may have antidepressive, anxiolytic, and antiaddictive properties. Thus, we conducted a systematic review of clinical trials published from 1990 until 2015, assessing these therapeutic properties. Electronic searches were performed using the PubMed, LILACS, and SciELO databases. Only clinical trials published in peer-reviewed journals were included. Of these, 151 studies were identified, of which six met the established criteria. Reviewed studies suggest beneficial effects for treatment-resistant depression, anxiety and depression associated with life-threatening diseases, and tobacco and alcohol dependence. All drugs were well tolerated. In conclusion, ayahuasca, psilocybin and LSD may be useful pharmacological tools for the treatment of drug dependence, and anxiety and mood disorders, especially in treatment-resistant patients. These drugs may also be useful pharmacological tools to understand psychiatric disorders and to develop new therapeutic agents."

"Professionals and experts seem to prefer the tragic explanation of why some choose drugs to get by more effortlessly in life. Tragic upbringing and sexual abuse, spiced with an alcoholized home, are "popular" explanations. (. . .) What I miss are all those who have in fact used and are using drugs because it feels good – so good that you do not want to stop even though you can see with open eyes that you are playing Russian roulette with everything and everybody that are close. Family, sweetheart, children. Yes, even life. (. . .) The reasons why people start to use drugs are plentifold. You encounter drug users in all social classes and segments of the population. But if there exists a common denominator, that would have to be the desire for a "recess". Recess from what? Well, that varies from one individual to the next. It is really a matter of drug users being as diverse as the rest of the population."

"It's an extremely profitable thing to be 'concerned' about drugs. You don't just have treatment programs, you have law enforcement programs, you have entire industries that could not function but for drugs. Including the prison industry. I think America has gone psychotic ... there are human beings—even as we speak—dying, in the kind of shrieking, tormenting pain you couldn't inflict on a P.O.W., because America doesn't want them to be drug addicts."

"The point of drugs, for me, was always the eternal moment when you felt like Jesus's son (and gender be damned); when you found your center, which is another word for sanity or, I assume, sobriety as Faith understands it. But I never found a drug that would guarantee me that moment, or even a more vulgar euphoria: acid, grass, speed, coke, even Quaaludes (I've never tried heroin), all were unpredictable, potentially treacherous, as likely to concentrate anxiety as to blow it away. Context was all-important-set and setting, as they called it in those days. My emotional state, amplified or undercut by the collective emotional atmosphere, made the difference between a good trip, a bad trip, or no trip at all. For me, the ability to get high (I don't mean only on drugs) flourished in the atmosphere of abandon that defined the '60s-that pervasive cultural invitation to leap boundaries, challenge limits, try anything, want everything, overload the senses, let go."

"I don't do drugs, nor have I ever believed in them. Am I a creative person? Then why do people think in order to be creative one must do drugs? Actually, I think people take them as an excuse to screw up in public, y'know, spill things or get silly. Drugs have slowed down civilization because we have to wait for people to get off their high before we can resume. They are the millstone around society's neck."

"Worldwide, pharmaceutical use has been on the increase for the past century and will continue to increase into the future with the development of new medicines to cure recently discovered diseases as well as previously untreatable conditions. Following use by the patient, active pharmaceutical ingredients (APIs) and their metabolites are excreted to the sewerage system. They are then typically transported to a wastewater treatment works, where, depending on their molecular structure and physicochemical properties, they can be either degraded by biological treatment processes or released to the environment in effluents or sorb to sludge. The soil environment will therefore be exposed to APIs and their metabolites when sludge from treatment processes is applied to land as an agricultural fertilizer or when soil is irrigated with reclaimed wastewater effluent. While only a few studies have explored the occurrence of APIs in the soil environment, available data indicate that a range of API classes, including nonsteroidal anti-inflammatory drugs, antidepressants, anticonvulsants, and antibacterial agents do occur in soils in concentrations up to the low mg/kg level. Because of detection of pharmaceuticals in soils, concerns have been raised over the potential for these substances to be taken up into human food items and to pose a risk to human health. A number of studies have demonstrated the uptake of pharmaceuticals used in human and veterinary medicine into plants. Studies have explored the uptake and translocation of a variety of APIs with a particular focus on the antidepressant drug fluoxetine and antibacterial chemicals including sulfamethazine, sulfamethoxazole, and trimethoprim into numerous plant species including root and shoot crops such as soybean, lettuce, and carrot."

""When a drug is ingested, it’s metabolized and what eventually is excreted is the portion of the original parent drug that doesn’t get metabolized, along with metabolites, which may have biological activity of their own,” says Christian Daughton, an environmental chemist from the Environmental Protection Agency. The amount that our bodies break down drugs varies widely, from drug to drug and even from person to person. For many drugs, Daughton says, about 90% of the drug is metabolized. Others aren't metabolized as much, and a lot of the parent compound is excreted. The undigested drugs and metabolites, the digested drugs, are either removed from the body as waste or sweat. These are either flushed down toilets are go down the drain in our showers."

"Although previously the monoamine systems were considered to be responsible for the development of major depressive disorder (MDD), the available evidence to date does not support a direct causal relationship with MDD. There is no simple direct correlation of serotonin or norepinephrine levels in the brain and mood. In other words, after a half-century of research, the chemical-imbalance hypothesis as promulgated by the drug companies that manufacture SSRIs and other antidepressants is not only without clear and consistent support, but has been disproved by experimental evidence."

"Did you know that of the 14 states with the highest number of painkiller prescriptions per person, they all went for Trump?"

"High-profile advertisements for the neuroleptic medication Stelazine in the American Journal of Psychiatry from the 1960s and 1970s unsubtly portrayed tribal masks and artwork during the precise moment in time that Malcolm X described a global African community, and Bromberg and Simon connected "African themes" with black psychotic symptoms."

"For decades, scientists have embarked on the long journey toward a medical breakthrough by first experimenting on laboratory animals. Mice or rats, pigs or dogs, they were usually male: Researchers avoided using female animals for fear that their reproductive cycles and hormone fluctuations would confound the results of delicately calibrated experiments. That laboratory tradition has had enormous consequences for women. Name a new drug or treatment, and odds are researchers know far more about its effect on men than on women. From sleeping pills to statins, women have been blindsided by side effects and dosage miscalculations that were not discovered until after the product hit the market."

"There were fewer than 3,000 overdose deaths in 1979, when a heroin epidemic was raging in U.S. cities. There were fewer than 5,000 recorded in 1988, around the height of the crack epidemic. More than 64,000 Americans died from drug overdoses last year [2016], according to the U.S. Centers for Disease Control and Prevention."

"“We have an aging demographic, and we have an increased reliance, in North America and Europe in particular, with the treatment of health concerns with pharmaceuticals.” This translates to more medicines making their way into the water system, and we need to determine how to deal with it, she says. “Long-term exposures [to pharmaceuticals] are quite a bit different than short term exposures, and we need to really start testing and figuring out if chronic exposures of low doses are relevant for the health of an individual or population of animals.”"

"If it were discovered today, it would be illegal as a foodstuff. The safe limit of alcohol, if you apply food standards criteria, would be one glass of wine a year."

"Alcohol abuse and alcoholism have a different physiologic effect on women than on men. Societal attitudes about women and alcohol and internal (self-perception) and external (environmental) factors can create barriers to the detection and treatment of female alcohol abusers."

"Who has woe? Who has uneasiness? Who has quarrels? Who has complaints? Who has wounds for no reason? Who has bleary eyes? Those lingering long over wine; those searching out mixed wine. Do not look at the wine's red color as it sparkles in the cup and goes down smoothly, for in the end it bites like a serpent, and it secretes poison like a viper. Your eyes will see strange things, and your heart will speak perverse things. And you will be like one lying down in the middle of the sea, like one lying at the top of a ship's mast. You will say: “They have struck me, but I did not feel it. They beat me, but I did not know it. When will I wake up? I need another drink.”"

"Perhaps the single greatest influence on the scope and direction of alcohol research has been the finding that a portion of the vulnerability to alcoholism is genetic. This finding, more than any other, helped to establish the biological basis of alcoholism. It also provided the basis—and justification—for much of the progress in genetics, neuroscience, and neurobehavior described in the Tenth Special Report. Today we know that approximately 50 to 60 percent of the risk for developing alcoholism is genetic. Genes direct the synthesis of proteins, and it is the proteins that drive and regulate critical chemical reactions throughout the human body. Genetics, therefore, affects virtually every facet of alcohol research, from neuroscience to Fetal Alcohol Syndrome."

"I drink out of desperation. Life is too dreary to endure. The misery, loneliness, crampedness — they're heartbreaking.[...] What feelings do you suppose a man has when he realizes that he will never know happiness or glory as long as he lives? Hard work. All that amounts to is food for the wild beasts of hunger."

"A custom loathsome to the eye, hateful to the nose, harmful to the brain, dangerous to the lungs, and in the black, stinking fume thereof nearest resembling the horrible Stygian smoke of the pit that is bottomless."

"A cigarette is the perfect type of a perfect pleasure. It is exquisite, and it leaves one unsatisfied. What more can one want?"

"I am of course notoriously hooked on cigarettes. I keep hoping the things will kill me. A fire at one end and a fool at the other."

"The Rastas, more than any other group, have elevated ganja to a central place in their religious practice and have developed a well-articulated ideology justifying its use and explaining its significance. ... Rastas regard the proscription of ganja use by Babylon's government as part of its strategy of social control."

"Please help me squash this deceptive and dangerous misrepresentation of my true feeling on this matter by the ONDCP. It just shows how desperate they are that they must mislead people in this way. And just so there is no question about this, let me be clear: Whole cannabis is not only the best medicine for me, it is the only medicine that has kept me alive during the 32 years that I have continued to live, in relatively good heath, despite a terminal diagnosis of malignant pheochromocytoma."

"When you smoke herb, herb reveal yourself to you. All the wickedness you do, the herb reveal itself to yourself, your conscience, show up yourself clear, because herb make you meditate. Is only a natural t'ing and it grow like a tree."

"I have repeatedly stated [cannabis] is not safe, but that the idea that you can reduce use through raising the classification in the Misuse of Drugs Act from class C to class B—where it had previously been placed, but thus now increasing the maximum penalty for possession for personal use to 5 years in prison—is implausible."

"Drivin' that train high on cocaine. Casey Jones you'd better watch your speed."

"A kilo of cocaine costs $50 in the trafficking countries and is sold in the consuming countries for $5,000 to $10,000, and so there always will be someone ready to run the risk of the illegitimate business."

"I shared a room with a female crack addict who also worked the streets. This was a completely alien thing to me and, at first, I was horrified but soon realised she was not so different to me."

"Without a flicker of hesitation I injected the morphine into my arm. My insecurity, fretfulness and timidity were swept away completely; I turned into an expansively optimistic and fluent talker. The injection made me forget how weak my body was, and I applied myself energetically to my cartoon."

"Ros was dead. He had loved heroin more than it loved him."

"The CIA looked the other way while Afghanistan’s opium production grew from about 100 tonnes annually in the 1970s to 2,000 tonnes by 1991. In 1979 and 1980, just as the CIA effort was beginning to ramp up, a network of heroin laboratories opened along the Afghan-Pakistan frontier. That region soon became the world’s largest heroin producer. By 1984, it supplied a staggering 60% of the US market and 80% of the European. Inside Pakistan, the number of heroin addicts surged from near zero (yes, zero) in 1979 to 5,000 in 1980, and 1.3 million by 1985 – a rate of addiction so high the UN termed it “particularly shocking”."