"We can see from these examples that, if the carbon atoms participating in the double bond are not equally substituted, the proton from the hydrogen halide attaches itself to the less substituted carbon.As a consequence, the halogen ends up at the more substituted carbon. This phenomenon, referred to as the Markovnikov rule,can be explained by what we know about the mechanism of electrophile additions of protons to alkenes. The key is the relative stability of the resulting carbocation intermediates. (...) On the basis of this analysis, we can rephrase the empirical Markovnikov rule: HX adds to unsymmetric alkenes in such a way that the initial rotonation gives the more stable carbocation."
Quote Details
Added by wikiquote-import-bot
Unverified quote
0 likes
Original Language: English
Available Languages (1)
Sources
K. Peter C. Vollhardt, Neil E. Schore (2011) Organic chemistry : structure and function 6th ed. Ch. 12 : Reactions of Alkenes
https://en.wikiquote.org/wiki/Vladimir_Markovnikov
Revision History
No revisions have been submitted for this quote.
Categories
Vladimir Markovnikov
Vladimir Vasilyevich Markovnikov, also spelled as Markownikoff (December 22, 1837 – February 11, 1904), was a Russian chemist.
3 quotes on TrueQuotesView all quotes by Vladimir Markovnikov →
Related Quotes
"Additions of hydrogen halides to alkenes are electrophilic reactions that begin with protonation of the double bond t…"
"Hydroboration – oxidation constitutes another method for hydrating alkenes. The initial addition is syn and regiosele…"
"... I was interested in cooking long before I even knew there was a computer. ... I started, I think when I was nine …"
"... Find something you really love. ... Don’t be afraid to change your mind if you find that you really love somethin…"
"Myhrvold, whose favortie adjective is "cool," does not conform to the Microsoft stereotype, although he has a master'…"
"Myhrvold first made his name in technology: he became the first chief technology officer of Microsoft after the compa…"
"The cost of carrying will weigh heavily on ers of all sorts. successully beat small town merchants because they creat…"
"The twilight of the twentieth century is driven by a mixture of technology and resources very like that which drove n…"
"A true Modernist revolution in food has begun only recently, as s such as began consciously developing gastronomic ex…"
"Technology contains no inherent moral directive—it empowers people, whatever their intent, good or evil. This has alw…"