"The world has arisen in some way or another. How it originated is the great question, and Darwin's theory, like all other attempts to explain the origin of life, is thus far merely conjectural. I believe he has not even made the best conjecture possible in the present state of our knowledge."
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Louis Agassiz, Evolution and Permanence of Type (1874).
https://en.wikiquote.org/wiki/Origin_of_life
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Origin of life
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