"The concepts of purposive behavior and teleology have long been associated with a mysterious, self-perfecting or goal-seeking capacity or final cause, usually of superhuman or super-natural origin. To move forward to the study of events, scientific thinking had to reject these beliefs in purpose and these concepts of teleological operations for a strictly mechanistic and deterministic view of nature. This mechanistic conception became firmly established with the demonstration that the universe was based on the operation of anonymous particles moving at random, in a disorderly fashion, giving rise, by their multiplicity, to order and regularity of a statistical nature, as in classical physics and gas laws. The unchallenged success of these concepts and methods in physics and astronomy, and later in chemistry, gave biology and physiology their major orientation. This approach to problems of organisms was reinforced by the analytical preoccupation of the Western European culture and languages. The basic assumptions of our traditions and the persistent implications of the language we use almost compel us to approach everything we study as composed of separate, discrete parts or factors which we must try to isolate and identify as potential causes. Hence, we derive our preoccupation with the study of the relation of two variables. We are witnessing today a search for new approaches, for new and more comprehensive concepts and for methods capable of dealing with the large wholes of organisms and personalities."