"Why is it OK for me to admit having used marijuana but not heroin? I know why, of course. Because most people have been led to believe that heroin is inherently a dangerous drug, whereas pot is just a harmless giggle. It's frustrating. Consider the remarks made by senator Bernie Sanders at the start of 2018 on this subject: "Marijuana is not the same as heroin. No one who has seriously studied the issue believes that marijuana should be classified as a Schedule I drug beside killer drugs like heroin." As politicians go, Sanders seems to be a fair-minded, well-intentioned individual. But his drug perspective is ignorant. Here's why: In order for a drug, any drug, to produce an effect in the brain, it must first bind to a unique site recognized by that drug. This site, this "receptor"-a specialized structure that recognizes and responds to a particular chemical-is endogenous, meaning that it's in all of us. We also have an endogenous chemical that binds to each of these receptors. That means, each of our brains contains heroin-like and THC-like chemicals and their corresponding receptors."