"Paresis, as it is generally called in preference to the old GPI or general paralysis of the insane, is characterized by symptoms of bewildering variety, confirming the description of syphilis as the Great Imitator or, because of this very wealth of its ultimate manifestations, the Aristocrat of Diseases. Paresis involves a meningoencephalitis which marks its onset by personality changes, mild at first but growing steadily worse. There is irritability, failure of memory and judgement, insomnia, slovenliness, aggression, confusion, delusion, manic depression, epileptiform convulsion, slurred speech, incontinence, emaciation, sensational psychosis, finally death. The act of careless bohemian love, anonymous, quick and uncondomized, is proved not to have been worth the trouble or money....."