"Hey, kid. [Li'l Petey: What?] Look up. You want to know something, kid? [Li'l Petey: What, Papa?] This world has a lot of problems. But it can never be a horrible place. 'Cause you're in it."

"[repeated line to Petey] Papa!"

"You know that I gotcha, buddy. [he and Greg fist-bump] Fam."

"Lil Rel Howery — Chief"

"Luenell Campbell — Milly"

"Yung Gravy — Mr. Whiskers"

"Billy Boyd — Seamus"

"Wait. Aren't dogs colorblind?"

"[to Butler] You're fired!"

"Yes! My 80-Hexotron Driodformigon is complete!"

"You're on thin ice, Dog Man. So don't mess this up. Now, sit! [Dog Man sits on a desk chair, which spins] Stay! [The chair comes to a stop] You only have one job to do: keep your eyes on those monitors. [pulls out a rubber ducky] So, if somebody breaks out your favorite chew toy, and waves it around, you… You look at the monitors! [pulls out a bone] And if somebody has a juicy and delicious treat, you're not gonna look at it. You… You look at the monitors! [takes off his hat, revealing an Eastern gray squirrel on his head] And if somebody just happens to have an Eastern gray squirrel, you… [grabs Dog Man, who tries to get the squirrel as it scurries away] No! Dog Man! Just sit here, and don't mess this up, or you'll lose your job!"

"How evil can one cat be?! [Petey: Pretty evil! Ha-ha-ha!]"

"Arise, my beastly building! Arise!"

"Greg, if anything happens to me, take care of my girlfriend, Alice, will you?"

"Part dog. Part man. All hero."

"Lucas Hopkins Calderon — Li'l Petey"

"Poppy Liu — Butler"

"Melissa Villaseñor (US version) Louise Redknapp (UK version) — Realtor"

"Kate Micucci — Dippy"

"Brian Hopkins — Big Jim"

"Cheri Oteri — Mayor of Ohkay City"

"Stephen Root — Grampa"

"Pete Davidson — Petey"

"Peter Hastings — Dog Man, Officer Knight, Greg the Dog, Harold's House"

"[from the trailer] Enough about this Dog Man! It's time to stop this super-cop!"

"[Sarah: How evil can one cat be?!] Pretty evil! Ha-ha-ha!"

"I need someone, who thinks like me, acts like me, and has a retched soul like me. I need another me!"

"[Li'l Petey: Do you have a car seat?] A what? [Li'l Petey: A kid's car seat.] You're a clone cat sitting in a flying mechanical bug. They don't make a car seat for that. [Li'l Petey: OK, Papa.]"

"Dog Man, get in here! Now!"

"Will you get outta here?! Go and arrest Petey, AND I DON'T CARE IF IT TAKES A MONTAGE!"

"Why do you always gotta lick the… [spits, censoring himself] …inside of my mouth?! [Dog Man grunts "I don't know"]"

"[from the trailer] This super-cop makes friends, solves crimes, and even plays piano for the old folks."

"Maybe, Flippy… Maybe you just need a friend."

"[repeated line; in a robotic voice] Destroy all do-gooders."

"Where are you, Petey, the World's Most Evilest Cat?!"

"[about teaming up with Megamind] I even drew up some new costume designs, see? [holds out pieces of paper] You'd be the brain so you'd get a little brain, wearing glasses on your costume or something, and since I'm the cool one, I'd have, like, two tanks swordfighting..."

"I'm the superhero, you're supposed to be with ME!"

"[to Megamind] Once your death ray hit, I've never felt so alive. So I borrowed a prop from a nearby nursing school. Metro Man was finally dead! And Music Man was born. [Roxie: Music Man?] That way I can keep my logo."

"What were you saying? I'm sorry, I was too busy saving your life!"

"Being a hero is for losers! It's work, work, work, 24/7, and for what? I only took the gig to get the girl, and it turns out Roxanne doesn't want anything to do for me. [Megamind: Roxanne Ritchi?] Yeah, Roxanne Ritchi. I saw her having dinner and making googly eyes at some intellectual dweeb."

"I started to realize, despite all my powers, each and every citizen of Metro City had something I didn't - a choice. Ever since I can remember, I've always had to be what this city wanted me to be. What about what I wanted to do? Then it suddenly hit me - I do have a choice! I can be whatever I wanna be! No one said that this hero thing had to be a lifetime gig. You can't just quit either. That's when I got the brilliant idea... to fake my death."

"[voiceover] So, this is how it ends. Normally I'd chalk this up to my last glorious failure. But not today! What can I say? Old habits die hard."

"[after Megamind and Minion break into his apartment room] Is this a robbery? Because the lady across the hall has way better stuff than me!"

"[from the trailer] Consider yourselves under new management."