Pollution

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April 10, 2026

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April 10, 2026

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"Worldwide, pharmaceutical use has been on the increase for the past century and will continue to increase into the future with the development of new medicines to cure recently discovered diseases as well as previously untreatable conditions. Following use by the patient, active pharmaceutical ingredients (APIs) and their metabolites are excreted to the sewerage system. They are then typically transported to a wastewater treatment works, where, depending on their molecular structure and physicochemical properties, they can be either degraded by biological treatment processes or released to the environment in effluents or sorb to sludge. The soil environment will therefore be exposed to APIs and their metabolites when sludge from treatment processes is applied to land as an agricultural fertilizer or when soil is irrigated with reclaimed wastewater effluent. While only a few studies have explored the occurrence of APIs in the soil environment, available data indicate that a range of API classes, including nonsteroidal anti-inflammatory drugs, antidepressants, anticonvulsants, and antibacterial agents do occur in soils in concentrations up to the low mg/kg level. Because of detection of pharmaceuticals in soils, concerns have been raised over the potential for these substances to be taken up into human food items and to pose a risk to human health. A number of studies have demonstrated the uptake of pharmaceuticals used in human and veterinary medicine into plants. Studies have explored the uptake and translocation of a variety of APIs with a particular focus on the antidepressant drug fluoxetine and antibacterial chemicals including sulfamethazine, sulfamethoxazole, and trimethoprim into numerous plant species including root and shoot crops such as soybean, lettuce, and carrot."

- Pollution

• 0 likes• health• environment• chemistry•
"“There’s been a fair amount of work done in both the U.S. and Canada as well as Europe that documents [pharmaceuticals] in wastewater and in water,” says Joanna Wilson, a biologist at McMaster University in Ontario, Canada. She studies how drugs in the water affect zebrafish, a tiny freshwater fish in the minnow family. More recent data shows that the same types of compounds are in drinking water. One study found several pharmaceuticals in treated tap water, including atenolol (a beta-blocker), carbamazepine (an anticonvulsant), gemfibrozil (an antilipidemic), meprobamate (an antianxiety medication), and phenytoin (an anticonvulsant). The concentrations of these compounds were very low, usually less than 10 nanograms per liter, which is parts per trillion. For reference, one part per trillion is equivalent to about one second in 64 years. “We have an aging demographic, and we have an increased reliance, in North America and Europe in particular, with the treatment of health concerns with pharmaceuticals.” This translates to more medicines making their way into the water system, and we need to determine how to deal with it, she says. “Long-term exposures [to pharmaceuticals] are quite a bit different than short term exposures, and we need to really start testing and figuring out if chronic exposures of low doses are relevant for the health of an individual or population of animals.”"

- Pollution

• 0 likes• health• environment• chemistry•