First Quote Added
April 10, 2026
Latest Quote Added
"Whether in some sense the universe is ultimately knowable depends not only on how many natural laws there are that encompass widely divergent phenomena, but also on whether we have the openness and the intellectual capacity to understand such laws. Our formulations of the regularities of nature are surely dependent on how the brain is built, but also, and to a significant degree, on how the universe is built. For myself, I like a universe that includes much that is unknown and, at the same time, much that is knowable. A universe in which everything is known would be static and dull, as boring as the heaven of some weak-minded theologians. A universe that is unknowable is no fit place for a thinking being. The ideal universe for us is one very much like the universe we inhabit. And I would guess that this is not really much of a coincidence."
"Our perceptions may be distorted by training and prejudice or merely because of the limitations of our sense organs, which, of course, perceive directly but a small fraction of the phenomena of the world. Even so straightforward a question as whether in the absence of friction a pound of lead falls faster than a gram of fluff was answered incorrectly by Aristotle and almost everyone else before the time of Galileo. Science is based on experiment, on a willingness to challenge old dogma, on an openness to see the universe as it really is. Accordingly, science sometimes requires courage—at the very least the courage to question the conventional wisdom."
"All inquiries carry with them some element of risk. There is no guarantee that the universe will conform to our predispositions. But I do not see how we can deal with the universe—both the outside and the inside universe—without studying it. The best way to avoid abuses is for the populace in general to be scientifically literate, to understand the implications of such investigations. In exchange for freedom of inquiry, scientists are obliged to explain their work. If science is considered a closed priesthood, too difficult and arcane for the average person to understand, the dangers of abuse are greater. But if science is a topic of general interest and concern—if both its delights and its social consequences are discussed regularly and competently in the schools, the press, and at the dinner table—we have greatly improved our prospects for learning how the world really is and for improving both it and us."
"Society corrupts the best of us. It is a little unfair, I think, to criticize a person for not sharing the enlightenment of a later epoch, but it is also profoundly saddening that such prejudices were so extremely pervasive. The question raises nagging uncertainties about which of the conventional truths of our own age will be considered unforgivable bigotry by the next."
"Broca was quoted as saying, “I would rather be a transformed ape than a degenerate son of Adam.”"
"The well-meaning contention that all ideas have equal merit seems to me little different from the disastrous contention that no ideas have any merit."
"That kind of skeptical, questioning, "don't accept what authority tells you" attitude of science — is also nearly identical to the attitude of mind necessary for a functioning democracy. Science and democracy have very consonant values and approaches, and I don't think you can have one without the other."
"Both borderline science and many religions are motivated in part by a serious concern about the nature of the universe and our role in it, and for this reason merit our consideration and regard. In addition, I think it possible that many religions involve at their cores an attempt to come to grips with profound mysteries of our individual life histories, as described in the last chapter. But both in borderline science and in organized religion there is much that is specious or dangerous. While the practitioners of such doctrines often wish there were no criticisms to which they are expected to reply, skeptical scrutiny is the means, in both science and religion, by which deep insights can be winnowed from deep nonsense."
"Natural selection has served as a kind of intellectual sieve, producing brains and intelligences increasingly competent to deal with the laws of nature. This resonance, extracted by natural selection, between our brains and the universe may help explain a quandary set by Einstein: The most incomprehensible property of the universe, he said, is that it is so comprehensible."
"Once intelligent beings achieve technology and the capacity for self-destruction of their species, the selective advantage of intelligence becomes more uncertain."
"The entire evolutionary record on our planet, particularly the record contained in fossil endocasts, illustrates a progressive tendency toward intelligence. There is nothing mysterious about this: smart organisms by and large survive better and leave more offspring than stupid ones."
"That in nonarithmetic operations the small and slow human brain can still do so much better than the large and fast electronic computer is an impressive tribute to how cleverly the brain is packaged and programmed—features brought about, of course, by natural selection. Those who possessed poorly programmed brains eventually did not live long enough to reproduce."
"To me it is not in the least demeaning that consciousness and intelligence are the result of “mere” matter sufficiently complexly arranged; on the contrary, it is an exalting tribute to the subtlety of matter and the laws of Nature."
"The integrity of the experimenters in the face of this unexpected finding is breathtaking. (It is difficult to imagine any experiment that would convince leading practitioners of many political or religious philosophies of the superiority of a competing doctrine.)"
"In general, human societies are not innovative. They are hierarchical and ritualistic. Suggestions for change are greeted with suspicion: they imply an unpleasant future variation in ritual and hierarchy: an exchange of one set of rituals for another, or perhaps for a less structured society with fewer rituals. And yet there are times when societies must change. “The dogmas of the quiet past are inadequate for the stormy present” was Abraham Lincoln’s description of this truth. Much of the difficulty in attempting to restructure American and other societies arises from this resistance by groups with vested interests in the status quo. Significant change might require those who are now high in the hierarchy to move downward many steps. This seems to them undesirable and is resisted."
"Anatomy is not destiny, but it is not irrelevant either."
"Without these experimental tests, very few physicists would have accepted general relativity. There are many hypotheses in physics of almost comparable brilliance and elegance that have been rejected because they did not survive such a confrontation with experiment. In my view, the human condition would be greatly improved if such confrontations and willingness to reject hypotheses were a regular part of our social, political, economic, religious and cultural lives."
"The search for patterns without critical analysis, and rigid skepticism without a search for patterns, are the antipodes of incomplete science. The effective pursuit of knowledge requires both functions."
"There is no way to tell whether the patterns extracted by the right hemisphere are real or imagined without subjecting them to left-hemisphere scrutiny. On the other hand, mere critical thinking, without creative and intuitive insights, without the search for new patterns, is sterile and doomed. To solve complex problems in changing circumstances requires the activity of both cerebral hemispheres: the path to the future lies through the corpus callosum."
"There is no doubt that right-hemisphere intuitive thinking may perceive patterns and connections too difficult for the left hemisphere; but it may also detect patterns where none exist. Skeptical and critical thinking is not a hallmark of the right hemisphere. And unalloyed right-hemisphere doctrines, particularly when they are invented during new and trying circumstances, may be erroneous or paranoid."
"Evolution often uses this strategy. Indeed, the standard evolutionary practice of increasing the amount of genetic information as organisms increase in complexity is accomplished by doubling part of the genetic material and then allowing the slow specialization of function of the redundant set."
"While ritual, emotion and reasoning are all significant aspects of human nature, the most nearly unique human characteristic is the ability to associate abstractly and to reason. Curiosity and the urge to solve problems are the emotional hallmarks of our species; and the most characteristically human activities are mathematics, science, technology, music and the arts--a somewhat broader range of subjects than is usually included under the “humanities.” Indeed, in its common usage this very word seems to reflect a peculiar narrowness of vision about what is human. Mathematics is as much a “humanity” as poetry."
"The price we pay for the anticipation of our future is anxiety about it. Foretelling disaster is probably not much fun; Pollyanna was much happier than Cassandra. But the Cassandric components of our nature are necessary for survival."
"There is a popular contention that half or more of the brain is unused. From an evolutionary point of view this would be quite extraordinary: why should it have evolved if it had no function? But actually the statement is made on very little evidence."
"Note that in all this interaction between mutation and natural selection, no moth is making a conscious effort to adapt to a changed environment. The process is random and statistical."
"A mutation in a DNA molecule within a chromosome of a skin cell in my index finger has no influence on heredity. Fingers are not involved, at least directly, in the propagation of the species."
"It is important to distinguish between the amount of information and the quality of that information."
"At any rate, both because of the clear trend in the recent history of biology and because there is not a shred of evidence to support it, I will not in these pages entertain any hypotheses on what used to be called the mind-body dualism, the idea that inhabiting the matter of the body is something made of quite different stuff, called mind."
"Those at too great a distance may, I am well aware, mistake ignorance for perspective."
"The entire recent history of biology shows that we are, to a remarkable degree, the results of the interactions of an extremely complex array of molecules; and the aspect of biology that was once considered its holy of holies, the nature of the genetic material, has now been fundamentally understood in terms of the chemistry of its constituent nucleic acids, DNA and RNA, and their operational agents, the proteins."
"Absence of evidence is not evidence of absence."
"My fundamental premise about the brain is that its workings—what we sometimes call “mind”—are a consequence of its anatomy and physiology, and nothing more."
"I proffer the following ideas with a substantial degree of trepidation; I know very well that many of them are speculative and can be proved or disproved on the anvil of experiment."
"I think the ratio, R, of the time to sense the dose taken to the time required to take an excessive dose is an important quantity. R is very large for LSD (which I've never taken) and reasonably short for cannabis. Small values of R should be one measure of the safety of psychedelic drugs. When cannabis is legalized, I hope to see this ratio as one of the parameters printed on the pack. I hope that time isn't too distant; the illegality of cannabis is outrageous, an impediment to full utilization of a drug which helps produce the serenity and insight, sensitivity and fellowship so desperately needed in this increasingly mad and dangerous world."
"My high is always reflective, peaceable, intellectually exciting, and sociable, unlike most alcohol highs, and there is never a hangover. Through the years I find that slightly smaller amounts of cannabis suffice to produce the same degree of high, and in one movie theater recently I found I could get high just by inhaling the cannabis smoke which permeated the theater. There is a very nice self-titering aspect to cannabis. Each puff is a very small dose; the time lag between inhaling a puff and sensing its effect is small; and there is no desire for more after the high is there."
"I can remember the night that I suddenly realized what it was like to be crazy, or nights when my feelings and perceptions were of a religious nature. I had a very accurate sense that these feelings and perceptions, written down casually, would not stand the usual critical scrutiny that is my stock in trade as a scientist. If I find in the morning a message from myself the night before informing me that there is a world around us which we barely sense, or that we can become one with the universe, or even that certain politicians are desperately frightened men, I may tend to disbelieve; but when I'm high I know about this disbelief. And so I have a tape in which I exhort myself to take such remarks seriously. I say "Listen closely, you sonofabitch of the morning! This stuff is real!" I try to show that my mind is working clearly; I recall the name of a high school acquaintance I have not thought of in thirty years; I describe the color, typography, and format of a book in another room and these memories do pass critical scrutiny in the morning. I am convinced that there are genuine and valid levels of perception available with cannabis (and probably with other drugs) which are, through the defects of our society and our educational system, unavailable to us without such drugs. Such a remark applies not only to self-awareness and to intellectual pursuits, but also to perceptions of real people, a vastly enhanced sensitivity to facial expression, intonations, and choice of words which sometimes yields a rapport so close it's as if two people are reading each other's minds."
"Note that I hold the single-author record for total CERT advisories, proving that in my copious youth I knew how to sling code but not how to manage risk."
"Fragmentation is like classful addressing -- an interesting early architectural error that shows how much experimentation was going on while IP was being designed."
"You sound like a man with a vision. Care to pass that bong over this way?"
"The internet has no government, no constitution, no laws, no rights, no police, no courts. Don't talk about fairness or innocence, and don't talk about what should be done. Instead, talk about what is being done and what will be done by the amorphous unreachable undefinable blob called the internet user base."
"personally i prefer the MX RR and a stylized name, but i was trying to solve the problem rather than create an industry."
"Isc remains deeply apologetic that prior versions of BIND did not properly catch the configuration error that you appear to have built your business on."
"Usually they finish by whining «but I WANT it!!! and so, I tell them: «So what? Everybody wants something. I want a pony. Get over it."
"While discussing the merits of djbdns over BIND (2004): Niek: "Bind people don't ack djb points and vice versa." Paul Vixie: i don't ack djb's existence, not merely his 'points.'"
"With usenet gone, we just don't teach our kids entertainment-level hyperbole any more."
"I've been lawsuit-threated [sic] by experts, and i can tell you from that experience, dv8 appears to not be an expert."
"The Internet is not for sissies."