"What I was trying to do with BioShock was to say, ‘Okay, well, [in Atlas Shrugged] that’s a utopia where Ayn Rand, who made the philosophy, made all the rules, and all the characters were under her control. What if things weren’t under everybody’s control?’ And I think that’s the problem with utopias — we bring ourselves to it, you know? We think we’re leaving our problems behind but – I don’t mean this in a cynical way – we are the problem. Like whatever social problems that occur come out of us. It’s not like they fall out of the sky. I think people think they’re going to go to a utopian society, and I think it’s not really possible."

"Anne Bobby – Brigid Tenenbaum"

"Can't somebody clean this place up? Scrub it down! It's crawling, crawling!"

"You call that tenderloin? If you serve that in any respectable hotel in New York, they'd laugh you out of town!"

"Go and run! That's all your time is good for!"

"When is a fever not a fever…? When I say it isn't!"

"T. Ryder Smith - Sander Cohen"

"All I wanna do is meet someone... but this fucking place is poison."

"Who needs to make it on Broadway theatre|Broadway? When you can make it here."

"She was up for the part as well, but then they found her in a salt pond."

"It's my part! Mine!"

"I know you're here! And I'm itching for a fight."

"Run, run to your devil! I'm sure HE will help you!"

"You gotta be rich, down here, to meet a lady. They don't care how nice you are."

"The lies, the money... the lies, The money..."

"Where is he Madonna? Where is the little sinner?"

"You know what they do to vagrants in Rapture? They hang them!"

"Nothing there, but we should bring in the hounds from the stables, just the same."

"I- I try to help, but- sometimes I- I make mistakes... I try to help! But sometimes I- I make mistakes."

"Toxic! Septic! UNSANITARY!"

"You're crawling! You're sick!"

"Armin Shimerman – Andrew Ryan"

"Greg Baldwin – Frank Fontaine"

"Closed the theater? Why? Because there's a war on? Bastards!"

"He died for you, for YOU, you SON OF A BITCH!""

"I traded You, oh Lord, for Mammon, and what did it get me, huh?!"

"You ungrateful bastard! He offered you salvation, and you shit on him!"

"What's that, fella'? You think I'm prettier than Garbo, huh? Well…"

"Things were supposed to work out for me, down here...! RYAN! When's my turn, you son of a bitch?!"

"[If player has saved every Little Sister] They offered you the city... And you refused it. And what did you do instead? What I have come to expect of you: You saved them. You gave them the one thing that was stolen from them: A chance. A chance to learn, to find love, to live. And in the end what was your reward? You never said, but I think I know... A family."

"[If player has harvested at least one Little Sister] They offered you everything, yes? And in return you gave them what you always did... brutality. You took what you wanted — all the ADAM, all the power — and Rapture trembled. But in the end even Rapture was not enough for you. Your father was terrified that the world would try to steal the secrets of his city. For you now have stolen the terrible secrets of the world."

"I was at German prison camp only of sixteen years old when I realize I have love for science. German doctor, he make experiment. Sometime, he make scientific error. I tell him of this error, and this make him angry. But then he asks, "How can a child know such a thing?" I tell him, "Sometimes, I just know." He screams at me, "Then why tell me?" "Well," I said, "if you're going to do such things, at least you should do them properly.""

"[about the cured Little Sisters] Ach, look at them. Even though they are physically free of the need to gather, Suchong's mental conditioning still holds them to their terrible task. For sins such as this we can never atone."

"It would mean very much to me if you will be gentle with the girls. Mein kleines maedchen."

"[If player has harvested every Little Sister] They offered you everything, yes. And in return you gave them what I have come to expect of you: brutality! You took what you wanted, all the ADAM, all the power! And Rapture trembled, but in the end even Rapture was not enough for you! Your father was terrified the world would try to steal the secrets of his city! But not you, for now have stolen the terrible secrets of the world!"

"This little Sea Slug has come along and glued together all the crazy ideas I've had since the war… it doesn't just heal damaged cells, it… resurrects them… I can bend the double helix… black can be reborn white, tall, short, weak, strong…"

"[after Fontaine escapes] Scheisse! You let him get away! I need a moment for thinking. Ah! Ach, of course! This will be no problem. Find a Big Daddy und search his body. I would suggest you to be finding a dead one."