"Hello, Xavier. I want to play a game. The game I want to play is very similar to the game you've been playing as a drug dealer. The game of offering hope to the desperate, for a price. I think we can agree that your situation is desperate. So, I offer you hope. The price you pay is that you must crawl into the same pit of squalor you force your customers into. By entering this room, you have started a timer. When the timer expires, the door in front of you will be locked forever. Only in finding the key before the timer runs out can you unlock it and retrieve the antidote inside. I will give you just one hint where to that key is: It will be like finding a needle in a haystack. Let the game begin."

"Hello, Obi. I want to play a game. For years you have burned those around you with your lies, cons, and deceits. Now you will have a chance to redeem yourself, for the games you've played with others, by playing one of mine. Inside the device in front of you are two antidotes for the poison coursing through your veins. One is my gift to you for helping me kidnap the others. The second is yours to donate. However, one will come with a price. Remember Obi: Once you are in Hell, only the devil can help you out."

"Greetings...and welcome. I trust that you are all wondering where you are. I can assure you that while your location is not important, what these walls offer you is important: salvation, if you earn it. Three hours from now, the door to this house will open. Unfortunately, you only have two hours to live. Right now, you are breathing in a deadly nerve agent. You've been breathing it since you arrived here. Those of you familiar with the Tokyo subway attacks will know its devastating effects on the human body. The only way to overcome it and walk out that door is to find an antidote. Several are hidden around this house. One is inside the safe in front of you. You all possess the combination to the safe. Think hard. The numbers are in the back of your mind. The clue to their order can be found over the rainbow. Once you realize what you all have in common, you will gain a better understanding of why you're here. X marks the spot for that clue, so look carefully. Let the game begin."

"Hello, Michael. I want to play a game. So far, in what loosely could be called your life, you have made a living watching others. Society would call you an informant, a rat, a snitch. I call you unworthy of the body you possess. Of the life you've been given. Now we will see if you are willing to look inward, rather than outward, to give up the one thing you rely on in order to go on living. The device around your neck is a death mask. The mask is on a string timer. If you do not locate the key in time, the mask will close. Think of it like a Venus Flytrap. What you're looking at right now is your own body, not more than two hours ago. Don't worry. You're sound asleep, and can't feel a thing. Taking into account that you are at a great disadvantage here, I am going to give you a hint as to where I have hidden the key. So listen carefully. The hint is this: [TV screen shows an x-ray.] It's right before your eyes. How much blood would you shed to stay alive, Michael? Live or die, make your choice."

"[Directing Eric to the house] It's the last house on the left."

"[Whilst Eric Matthews has forced a pistol into his mouth] Game—Game over. I'll take you to the house."

"Not long to go now until your son is pissing blood."

"What would you have done five years ago? Would you have followed the manual then? Would you have broken my jaw with a flashlight?"

"I want to play a game."

"Tony Nappo - Gus Colyard"

"Noam Jenkins - Michael Marks"

"Lyriq Brent - Officer Daniel Rigg"

"Dina Meyer - Detective Allison Kerry"

"Tim Burd - Obi Tate"

"Beverley Mitchell - Laura Hunter"

"Emmanuelle Vaugier - Addison Corday"

"Glenn Plummer - Jonas Singer"

"Franky G - Xavier Chavez"

"Erik Knudsen - Daniel Matthews"

"Donnie Wahlberg - Detective Eric Matthews"

"Shawnee Smith - Amanda Young"

"Tobin Bell - Jigsaw / John"

"Your eye or your life?"

"Jigsaw is back to dish out"

"Oh Yes, There Will Be Blood"

"It's just me and that's the way I like it."

"[To Addison] Look who's talking. The only door you know how to open...is between your legs!"

"All I'm saying is let's just take our time and come up with a game plan"

"You remind me of me. No matter what kind of fucked-up situation you're in, you always got to find yourself a enemy. You know what? I got enemies, man. Outside these fucking walls, bro. And they're looking for me. And if they don't find me, they're going after the ones closest to me. My family. You understand?"

"You and me, we can keep going at each other like we're back in the yard, or we can come together and figure out who's doing this to us."

"Whatever we do, we've got three minutes to get it done."

"In death, there are no accidents, no coincidences, no mishaps, and no escapes. You have to realize that we're all just a mouse that a cat has by the tail. Every single move we make, from the mundane to the monumental, the red light that we stop at or run, the people we have sex with or want with us, the airplanes that we ride or walk out of—it's all part of Death's sadistic design leading to the grave."

"Amanda Detmer - Terry Chaney"

"Tony Todd - William Bludworth"

"Seann William Scott - Billy Hitchcock"

"Chad E. Donella - Tod Waggner"

"Roger Guenveur Smith - Agent Schreck"

"Daniel Roebuck - Agent Weine"

"Kristen Cloke - Valerie Lewton"

"Kerr Smith - Carter Horton"

"Ali Larter - Clear Rivers"

"Devon Sawa - Alex Browning"

"You may get a second chance at life. But you can't cheat Death."