"Don't worry, Shepard. I only forget to recycle the Normandy's oxygen when I've discovered something truly interesting. [pause, Shepard is shocked] That is a joke."

"[From the EC 'Synthesis' Ending] I am alive. All of us, synthetic and organic, have been changed. The war is over, and the Reapers are helping to rebuild. Where once they threatened us with extinction, they now bring us the collective knowledge of the cultures that came before. As a galaxy, we can now live the lives we have wished for; taking our steps into a new and wonderful future, where organics and synthetics can coexist peacefully. With peace across the galaxy and unlimited access to knowledge, to recover the greatness that was lost, and surpass it. We will reclaim our worlds...and the stars. As the line between synthetic and organic disappears, we may transcend mortality itself, to reach a level of existence I cannot even imagine. And we will remember that this chance for a new life did not come without cost. No matter how far we advance, we will remember the sacrifices of those who made it possible. And we will remember Shepard. Because of him/her, I am alive, and I am not alone."

"Shepard, you're staring..."

"I enjoy the sight of humans on their knees."

"That was a joke."

"This is loco!"

"Do you hear that hum? Is that just me?"

"Commander, didn't you tell Cerberus to go to hell after you destroyed the Collector Base?"

"[Seeing a Reaper Brute for the first time] Holy hell, what is that thing?!"

"[After seeing a rachni spore pod explode, which harms their shields] They explode? Really?!"

"[To Shepard, after encountering Rachni] Rachni!? Of all the... It's like you have the opposite of a horseshoe up your ass."

"[Firing on Reaper husks] Maybe I can get three at a time. Wahoo!"

"[Running with Shepard towards a Reaper destroyer that's firing at them] Are we really doing this?!"

"I just had a goddamn Reaper fire at me."

"Thanks for the dance, Loco."

"So...Anderson and Sanders. That's quite a couple. Hey, my father's last name is Sanders...no relation."

"[to a shocked commitee of Alliance leaders asking what to do] The only thing we can do. We fight or we die!"

"[to a dying Reaper; Renegade] Tell your friends we're coming for them! [calls another orbital strike] Never mind. I'll tell them myself."

"[from trailer] There's a lot of people back on Earth dying while we gather our strength. They're wondering if we're ever coming back; friends, family, parents and children. This isn't their fight, but they're buying us time with their lives."

"The Reapers won't stop at Earth. They'll destroy every organic being in the galaxy if we don't find a way to stop them."

"Each of us needs to be willing to die to save humanity. Anything less...and they've already won!"

"“If we reduce this war to arithmetic, we’re no better than Reapers.” -to Garrus"

"“There will be casualties, I just wonder how many?”"

"“Thinking of some friends who aren’t around thanks to this war.” - to Liara"

"“I will protect and sustain. I will act as guardian for the many.”"

"[Renegade] I've had enough of your tabloid journalism. [just before punching a news reporter]"

"You...big stupid jellyfish! [speaking to a Hanar - a race of jellyfish-like creatures]"

"[stabs Kai Leng] That was for Thane/Kirrahe (and Miranda), you son-of-a-bitch! [varies depending on who Leng killed]"

"[fighting Kai Leng] No gunship this time, you son-of-a-bitch!"

"[ordering the Quarian fleet to stand down] The Geth don't want to fight you! If you can believe that for just one minute, this war will be over. You have a choice. Please. Keelah Se'lai."

"That's a straw, Tali. [on her use of an "emergency induction port" to get drunk]"

"I bet you say that to every guy who gets you a homeworld. [to Tali after helping her retake her homeworld]"

"Unless we plan on talking the Reapers to death, the defense committee is a waste of time."

"Each of you needs to be willing to die. Anything less...and you're already dead."

"[Final speech - Comrades] This war's brought us pain, and suffering, and loss. But it's also brought us together, as soldiers, allies... friends. This bond that ties us together is something that the Reapers will never understand. It's more powerful than any weapon, stronger than any ship. It can't be taken or destroyed."

"[Final speech - Remember what you fight for] The next few hours will decide the fate of everyone in the galaxy. Every mother. Every son. Every unborn child. They're trusting you. Depending on you to win them their future. A future free from the threat of the Reapers!"

"[Final speech - Be fearless] But take heart! Look around you! You're not in this fight alone. We face our enemy together, and together, we will defeat them!"

"[to the Catalyst, from the Extended Cut 'Refusal' Ending] I fight for freedom. Mine, and everyone's. I fight for the right to choose our own fate. And if I die, I'll die knowing that I did everything I could to stop you. And I'll die free."

"[From the EC 'Control' Ending] Eternal. Infinite. Immortal. The man/woman I was used these words, but only now do I truly understand them. [If Paragon] And only now do I understand the full extent of his/her sacrifice./ [If Renegade] And only now do I comprehend the full potential of his/her decision. Through his/her death, I was created. Through my birth, his/her thoughts were freed. They guide me now; give me reason, direction. Just as he/she gave direction to the ones who followed him/her, the ones who helped him/her achieve his/her purpose; now my purpose. To give the many hope for a future; to ensure that all have a voice in their future. / To right the wrongs of the past; to provide a voice to those too weak to speak for themselves. [Or alternatively] To provide the many with a powerful leader; to put an end to the bickering of the many; to ensure the strongest are not feared or reviled for their strength. The man/woman I was knew that he/she could only achieve this by becoming something greater. There is power in control. There is wisdom in harnessing the strengths of your enemy. I will rebuild what the many have lost; I will create a future with limitless possibilities; I will protect, and sustain; I will act as guardian for the many. / I will restore what the many have fought for; I will lead an army that none will dare oppose; I will protect, defend; I will destroy those who threaten the future of the many. And throughout it all, I will never forget; I will remember the ones who sacrificed themselves so that the many could survive. And I will watch over the ones who live on / And I will keep a watchful eye over the ones who live on; those who carry the memory of the man/woman I once was, the man/woman who gave up his/her life / who fought to become the one who could save/lead the many."

"[Gazing at a Sovereign-Class Reaper on Menae] Look at that. And they want my advice on how to stop it? Failed C-Sec officer, vigilante, and I'm their expert adviser?"

"Are you kidding? I'm right behind you! [upon first meeting him on Menae]"

"[when lacking other dialogue or opinion] So who needs their ass kicked now?"

"Oh, I'm ready for it, but I'm pretty sure we'll still need giant guns... and lots of them. Sovereign didn't go down without a fight; I doubt a thousand more of his friends will be any different."

"Now I'd love to chat, but this gun really needs calibrating."

"[after witnessing the insectoid race of Rachni for the second time in the series] If I never see another spider again, I'll die a contented Turian... unless they have spiders in the afterlife. Damn."

"That's the thing about getting old, Shepard... the platitudes get just as old."

"It's something Turians are taught from birth. If even one person is still left standing at the end of a war, then the fight was worth it."

"Forgive the insubordination, but this old friend has an order for you...Go out there and give them hell. You were born to do this. [during the Battle of Earth]"