"The truth is, Carla, I'm a big man. Now I will lose weight, but I'm always gonna be big no matter what I do. So anyone I end up with is just going to have to accept me for who I am. More importantly, I'm going to have to accept myself for who I am."

"If you give me a moment, I believe I can try to explain. My research is, um... Well, when I started out, I wanted to help people. But I became desperate and selfish. What I did was wrong. Buddy's who I thought the whole world wanted me to be. He's who I thought I wanted to be. And sometimes when you want something so so bad, you do just about anything to get it. But I learned one thing from Buddy. I learned that life isn't about being happy with how much you weigh, but just being happy with yourself. I'm terribly sorry about all of this, I hope I haven't ruined everybody's evening. Please excuse me. I'm sorry."

"I heard of dreadlocks, but shitlocks?"

"Joe Morton — Cab Chamberlain"

"The Louisiana Gator Boys — Themselves"

"Paul Shaffer — Marco"

"James Brown — Reverend Cleophus James"

"Sam Moore — Reverend Morris"

"Jeff Morris — Bob"

"Wilson Pickett — Himself"

"Eddie Floyd — Himself"

"Murphy "Murph" Dunne — Himself"

"Jonny Lang — Custodian"

"Alan "Mr. Fabulous" Rubin — Himself"

"Tom "Bones" Malone — Himself"

"Steve "The Colonel" Cropper — Himself"

"Donald "Duck" Dunn — Himself"

"Aretha Franklin — Mrs. Murphy"

""Blue Lou" Marini — Himself"

"Matt "Guitar" Murphy — Himself"

"Willie "Too Big" Hall — Himself"

"Lonnie Brooks — Himself"

"Junior Wells — Himself"

"B. B. King — Malvern Gasperon"

"Erykah Badu — Queen Mousette"

"Darrell Hammond — Robertson"

"Steve Lawrence — Maury Sline"

"Frank Oz — Warden"

"J. Evan Bonifant — Buster Blues"

"Kathleen Freeman — Mother Mary Stigmata"

"Nia Peeples — Lieutenant Elizondo"

"John Goodman — "Mighty" Mack McTeer"

"Dan Aykroyd — Elwood Blues"

"The Blues are Back."

"You know, the only thing that kills the demon... is love."

"O-Lan Jones - Mabel"

"Corey Everson - Mallory Knox in TV reconstruction"

"Dale Dye - Dale Wrigley"

"Louis Lombardi - Deputy "Sparky""

"Grand L. Bush - Prison inmate"

"Peter Crombie - Intense cop"

"Marshall Bell - Deputy"

"Everett Quinton - Deputy Wurlitzer"

"Joe Grifasi - Deputy Sheriff Duncan Homolka"

"Pruitt Taylor Vince - Deputy Warden Kavanaugh"