"What I was trying to do with BioShock was to say, ‘Okay, well, [in Atlas Shrugged] that’s a utopia where Ayn Rand, who made the philosophy, made all the rules, and all the characters were under her control. What if things weren’t under everybody’s control?’ And I think that’s the problem with utopias — we bring ourselves to it, you know? We think we’re leaving our problems behind but – I don’t mean this in a cynical way – we are the problem. Like whatever social problems that occur come out of us. It’s not like they fall out of the sky. I think people think they’re going to go to a utopian society, and I think it’s not really possible."

"Armin Shimerman – Andrew Ryan"

"Greg Baldwin – Frank Fontaine"

"Karl Hanover – Atlas"

"Anne Bobby – Brigid Tenenbaum"

"T. Ryder Smith - Sander Cohen"

"Peter Francis James – Dr. J.S. Steinman"

"Susanne Blakeslee – Prof. Julie Langford"

"Juliet Landau – Little Sisters"

"Where is he Madonna? Where is the little sinner?"

"You ungrateful bastard! He offered you salvation, and you shit on him!"

"He died for you, for YOU, you SON OF A BITCH!""

"I traded You, oh Lord, for Mammon, and what did it get me, huh?!"

"[to the tune of Frere Jaques] Mr. Bubbles, Mr. Bubbles, are you there? Are you there? Come and give me lollies, come and bring me toffees. Teddy bears… teddy bears."

"This little Sea Slug has come along and glued together all the crazy ideas I've had since the war… it doesn't just heal damaged cells, it… resurrects them… I can bend the double helix… black can be reborn white, tall, short, weak, strong…"

"I was at German prison camp only of sixteen years old when I realize I have love for science. German doctor, he make experiment. Sometime, he make scientific error. I tell him of this error, and this make him angry. But then he asks, "How can a child know such a thing?" I tell him, "Sometimes, I just know." He screams at me, "Then why tell me?" "Well," I said, "if you're going to do such things, at least you should do them properly.""

"[If player has saved every Little Sister] They offered you the city... And you refused it. And what did you do instead? What I have come to expect of you: You saved them. You gave them the one thing that was stolen from them: A chance. A chance to learn, to find love, to live. And in the end what was your reward? You never said, but I think I know... A family."

"Rapture is coming back to life. Even now, can't you hear the breath returning to her lung? The shops reopening, the schools humming with the thoughts of young minds? My city will live. My city will thrive. And, when that day comes, we'll use your tombstone for paving tiles."

"They told me, "Son, you're special, you were born to do great things." You know what? They were right."

"Would you kindly pick up that ? [when the player does so] I don't know how you survived that plane crash, but I've never been one to question Providence. I'm Atlas, and I aim to keep you alive. Now keep on moving... we're gonna have to get you to higher ground. Take a deep breath and step out of the . I won't leave you twisting in the wind."

"Now, would you kindly find a or something? Bloody Splicers sealed Johnny in before they... Goddamn Splicers."

"Listen – I've got a family. I need to get them out of here. But the Splicers have cut me off from them. If you can reach them in Neptune's Bounty, then maybe, just maybe... I know you must feel like the unluckiest man in the world right now, but you're the only hope I'll ever see my wife and child again. Go to Neptune's Bounty... Find my family... Please."

"Plasmids changed everything. They destroyed our bodies, our minds. We couldn't handle it. Best friends butchering one another, babies strangled in cribs. The whole city went to hell."

"Careful now... Would you kindly lower that weapon for a minute? [when the player sees the Little Sister harvesting a corpse] You think that's a child down there? Don't be fooled. She's a Little Sister now. Somebody went and turned a sweet baby girl into a monster. Whatever you thought about right and wrong on the surface, well, that don't count for much down in Rapture. Those Little Sisters, they carry ADAM – the genetic material that keeps the wheels of Rapture turning. Everybody wants it; everybody needs it. [a Splicer approaches the Little Sister, who then screams, causing the Big Daddy to appear] That's the Big Daddy. She gathers ADAM, he keeps her safe."

"[after the player escapes from the Welcome Center] Now you've met Andrew Ryan, the bloody King of Rapture. Now find your way to Emergency Access."

"If you want to use the Emergency Access, you'll be needing Dr. Steinman's key. He's the one what runs this place. But I don't expect him to hand it to you out of the milk of human kindness. Steinman ain't that kind, and frankly, I'm not even sure he's still human."

"All roads in Rapture lead to Ryan. The security, the Splicers, the Big Daddies, the Little Sisters: he pumps some kind of chemical scent in the air, pheromones they call it, makes them all dance to his tune."

"[encountering the first Little Sister to either harvest or rescue] Listen, boyo: You won't survive without the ADAM those... Things... Are carrying. Are you prepared to trade your life, the lives of my wife and child for Tenenbaum's little Frankensteins?"

"[if the player chooses to harvest the first Little Sister] That ADAM should do the trick. You did the right thing. Just remember: them things aren't people no more. And it's Dr. Tenenbaum they've got to thank for it."

"[if the player chooses to save the first Little Sister] Tenenbaum's playing you for a sap. Those things may look like wee little girls, but looks don't make it so. You'll need all the ADAM you can get to survive."

"Now you've had the pleasure of Andrew Ryan's company. He's the one who built this place, and he's the one who run it into the ground. Nobody knows exactly what happened. Maybe he went mad. Maybe the power got to him. Maybe he just decided he didn't like people. Whichever way you slice it, good men died."

"[about Peach Wilkins] Grown man, jumping at ghosts. Fontaine's dead and everybody knows it. In the ground for months, and half the place still jumping at his shadow. Christ, even Ryan. You never mind all that. We got work to do."

"Me wife, Moira – she's a right pain in the neck. But she's a beauty and she means the world to me. I can't help but feel God's punishing me for bringing her and Patrick to this place. I thought this would be a better life for us. Can you imagine a bigger fool than that?"

"[devastated] Moira... Patrick... Ain't that just like Ryan. Waits until we're almost out, and then he pulls the string! We'll find the bastard! We'll find him and we'll tear his heart out!"

"[when the player encounter propaganda posters about him] You might hear things about me, see my name about. Think what you will. There was a time when I cared about politics, but it's just an excuse men use to kill one another. I'm done with all that. I just want to see the sunlight again."

"I'm gonna need you to listen to me. I'm no sort of botanist, but I think Ryan has just killed Arcadia. The man's put something foul into the air. Bottom of the ocean, boyo. All the oxygen comes from the trees. No trees, no oxygen. Give me a spell to think... Ryan's woman in Arcadia is an old betty named Langford. An okay sort, but not above doing a dirty job for a dollar. If she's still kicking around, I'm sure she's gonna want to save her trees. After all, she planted the damn things."

"[after Ryan poisons Langford] Every time we get a yard ahead, Ryan goes and moves the goal line down to the other side of the field!"