"[Referring to the anti-radiation red cigarettes] I can't believe you've got to put this shit in your lungs just to neutralize the shit in your lungs."

"What are they supposed to look like?"

"You just got out of basic training, didn't you? It's pretty obvious you're a rookie. You think you're the center of the universe but you're not. We're just insignificant little specks, you and me. We're not gonna change the world. we're not gonna win the war. Nobody's gonna care when we die."

"Initially, we had a very loose idea of how we would bring Wolverine back in ways that don't necessarily interact or interfere with Logan and that legacy. I know Kevin, like Shawn and I and Hugh, were all very concerned about that. We really needed to protect that and still allow us to tell the most full-throated Wolverine story we could ever imagine, which for us was just a huge nerve-wracking privilege."

"That's right - Pinnochio's not a real little boy!"

"Turns out, I am the world-saving type. Just look around this table if you want proof. The best part? Sometimes, the people we save... Well, they save us right back."

"Hugh’s performance gives the movie a gravitas and a raw, soulful quality that is unbelievable, and I can't say much more without spoiling it. It's among the things that differentiate the movie from prior X-Men or Deadpool movies. The duo differentiates it. The fact that Logan is with a comedic engine for the entirety of the movie changes everything."

"Ryan Reynolds – Wade Wilson / Deadpool & Nicepool"

"Things ain't what they used to be."

"You mean who are they supposed to look like?"

"(in a post-credit scene; breaking the fourth wall) I’m tired of these absolutely vile rumors that I got Johnny killed. Let’s look at the tape. [showcases the footage of his and Logan's conversation with Johnny Storm in the Void] Gotcha, fuck face."

"Chris Hemsworth - Thor"

"Jon Favreau - Happy Hogan"

"Wunmi Mosaku - Hunter B-15"

"Chris Evans - Steve Rogers / Captain America & Johnny Storm / The Human Torch"

"Peggy - Dogpool"

"[Voice over narration] For the last fifty years, the new economic block, the 'N.E.B.' Corporation, has controlled mining operations throughout the known solar systems."

"Dafne Keen - Laura Kinney / X-23"

"Tyler Mane - Sabretooth"

"Jennifer Garner - Elektra Natchios"

"Wesley Snipes - Blade"

"Aaron Stanford - Pyro"

"Lewis Tan – Shatterstar"

"We can smile, we can cry. We can bleed... we can fuck."

"Channing Tatum - Gambit"

"Laura Kinney / X-23: You remind me of him. Angry. Drunk. Mean. [...] Showed up when it mattered the most. Couldn't help it."

"Leslie Uggams – Blind Al"

"Stefan Kapičić – Colossus"

"Blade: There's only ever been one Blade. There's only ever gonna be one Blade."

"Johnny Storm: You see anyone running, dick-for-brains? You're not gonna love what happens next."

"Vanessa: Ever since they turned you down, you took a knee... Baby, you never got back up. I know you're going through something, let me go through it with you."

"Gambit: You know how long I been waitin' for this? Woo, I'm about to make a name for myself here!"

"Gambit: I ain't know my daddy, but I'm sure I shot outta his dick ready. [...] Yeah, he was laying them buttery nuts all up in my mama and I shot out there and I said "what's up, doc?""

"Brianna Hildebrand – Negasonic Teenage Warhead"

"(in a post-credit scene; Deadpool is in a TVA control room)"

"Blind Al: I pray every day that fire finds your body and finishes the job God didn't have the nuts to do!"

"Paradox: I have been tasked with overseeing the end of your universe and, regardless of what the pencil-pushers upstairs would prefer, I will not waste my life watching it die slowly of natural causes. We used to just prune these things -- Simple. Elegant. Efficient. But I'm told the TVA doesn't like to do that anymore. Well, I do. And no matter what my so-called superiors say, the multiverse does not need a babysitter. We need a mercy killer. And in this instance, I am the mercy killer!"

"Jefferson, you must be confusing me with someone who gives a shit."