"[to Katherine] I’m sorry, but, I’m going to have to call you on that. It’s bullshit. That’s what everyone has been saying. “You’ll get better” and “It’ll be fine”. I don’t know why everyone is so fucking scared to say it. “You’re dying, dude”...It makes it worse."

"[to Adam] You’ll be fine. 50/50! If you were a casino game you’d have the best odds!"

"Matt Frewer - Mitch Barnett"

"Philip Baker Hall - Alan Lombardo"

"[to Adam, the night before Adam's surgery] Driving! That’s what you want to do? That’s your “Make A Wish”? To drive? We could be having sex with hookers while skydiving, and instead you want to do something I learned to do when I was fifteen!"

"Tim Burton - Brian"

"Tom Skerritt - Mayor Weber"

"Ally Walker - Pam"

"Jeremy Piven - Doug Hughley"

"Matt Dillon - Cliff Poncier"

"Jim True-Frost - David Bailey"

"Bill Pullman - Dr. Jeffrey Jamison"

"James LeGros - Andy"

"Eric Stoltz - The Mime"

"Linda, uh, it's me. I had to call you. It's about midnight. I was just having many beers. And, uh, I just wanted to say what I should have said at the dock. I fucking chickened out when I acted casual, like Mr. Casual. I should have said it. You... belong... with... me! We belong together. And what really pisses me off is that, now that we're really talking, you thought I proposed to you only because you were pregnant. What's that about?! I mean... hey, this is not the bathroom! And you know maybe if I had said some of these things at the dock it would have made a difference because... but I think we made a big mistake because...we had good times and we had bad times, but we had times. And I would like to start over. I would like to be new to you. I want to be new to you. I want to be Mr. New. So call me back if you want to. But this is the last time I'll call. And, if you really needed to know how I feel, how I really feel, that's how I feel. I love you. And that's something you should know, so I won't bother you again. So, good night. And good bye. And call me back. Good bye."

"Bridget Fonda - Janet Livermore"

"I broke up with someone recently: Jennifer, my last girlfriend. I did it in a crowded restaurant. She just stared at me with that look: How can you pass me up? I told her we weren't right and all the stuff we both knew. A week later I realized I was wrong, tried to get back together with her. She won't see me. Now she's with Tony. Tony knows my friend Bailey, who's friends with the girl Tony's going out with on the side, Rita. Rita who I broke up with to go out with Jennifer. So now do I tell Jennifer that I know Tony's going out with Rita or do I tell Rita that I know about Tony and Jennifer? Tony will tell Jennifer that I was still going out with Rita while I was going out with her. How does stuff get so complicated? I don't know."

"Kyra Sedgwick - Linda Powell"

"Somewhere around 25, bizarre becomes immature."

"Campbell Scott - Steve Dunne"

"I think that, a) you have an act, and that, b) not having an act is your act."

"You're Dr. Jamison, man. Many, many babes are into that."

"People need people, Steve. It has nothing to do with sex. OK, maybe 40 percent. 60 percent. Forget it."

"I've always been able to do this, break up with someone and never look back. Being alone: there's a certain dignity to it."

"Sheila Kelley - Debbie Hunt"

"Ian Tracey - Caylor Reese"

"Jackson Davies - FBI Agent Lusk"

"Earl Billings - Capt. Giles"

"Forest Whitaker - Det. Jack Pismo"

"Dan Lauria - Det. Phil Coldshank"

"Emilio Estevez - Det. Bill Reimers"

"Aidan Quinn - Richard "Stick" Montgomery"

"Richard Dreyfuss - Det. Chris Lecce"

"Who Says A Little Danger Can't Be A Lot Of Fun?"

"It's a tough job but somebody's got to do it!"

"Madeleine Stowe - Maria McGuire"

"Christopher Doyle - McNamara"

"Sharon Schaffer - Tilghman"

"Sharon Maughan - Barbara Burnside"

"Cathy Moriarty - Luella Delano"

"John Rubinstein - D.A. Thomas Hassrick"

"Dan Lauria - Capt. Phil Coldshank"