"Yo, Mike? You gonna visit my distinguished ass in California? You know, I'm planning on gettin' rich. I'm thinking of hiring Eddie Murphy to come over and tell you some jokes until you crack a damn smile. No? Well, how about Richard Pryor? Bill Cosby? Now, I know you like Bill Cosby. [In Bill Cosby voice] Mike Winchell, you do a good job of handing Boobie Miles the ball, and once in a while you throw a pretty good pass, so you make sure to eat your Jell-O Pudding Pops. Waaaaaahhh!"

"Being perfect is not about that scoreboard out there. It's not about winning. It's about you and your relationship with yourself, your family and your friends. Being perfect is about being able to look your friends in the eye and know that you didn't let them down because you told them the truth. And that truth is you did everything you could. There wasn't one more thing you could've done. Can you live in that moment as best you can, with clear eyes, and love in your heart, with joy in your heart? If you can do that gentleman - you're perfect!"

"I want you to take a moment, and I want you to look each other in the eyes. I want you to put each other in your hearts forever because forever is about to happen here in just a few minutes. I want you to close your eyes, and I want you to think about Boobie Miles, who is your brother. And he would die to be out there in that field with you tonight. And I want you to put that in your hearts. Boys my heart is full. My heart is full."

"Gentlemen, the hopes and dreams of an entire town are riding on your shoulders. You may never matter again in your life as much as you do right now."

"I've seen you fight. I've seen you not quit. Can you give me a great effort and just a little bit more. Can you be perfect?"

"Royce Clayton - Miguel Tejada"

"Arliss Howard - John W. Henry"

"Spike Jonze - Alán"

"Ken Medlock - Grady Fuson"

"Kerris Dorsey - Casey Beane"

"Robin Wright - Sharon"

"David Hutchison - John Mabry"

"Stephen Bishop - David Justice"

"Casey Bond - Chad Bradford"

"Chris Pratt - Scott Hatteberg"

"Philip Seymour Hoffman - Art Howe"

"Jonah Hill - Peter Brant"

"Brad Pitt - Billy Beane"

"There is an epidemic failure within the game to understand what is really happening. And this leads people who run Major League Baseball teams to misjudge their players and mismanage their teams. I apologize. (Billy Beane: Go on.) Okay. People who run ball clubs, they think in terms of buying players. Your goal shouldn't be to buy players, your goal should be to buy wins. And in order to buy wins, you need to buy runs. You're trying to replace Johnny Damon. The Boston Red Sox see Johnny Damon and they see a star who's worth seven and half million dollars a year. When I see Johnny Damon, what I see is... is... an imperfect understanding of where runs come from. The guy's got a great glove. He's a decent leadoff hitter. He can steal bases. But is he worth the seven and half million dollars a year that the Boston Red Sox are paying him? No. No. Baseball thinking is medieval. They are asking all the wrong questions. And if I say it to anybody, I'm-I'm ostracized. I'm-I'm-I'm a leper. So that's why I'm-I'm cagey about this with you. That's why I... I respect you, Mr. Beane, and if you want full disclosure, I think it's a good thing that you got Damon off your payroll. I think it opens up all kinds of interesting possibilities."

"[Addressing his baseball scouts] The problem we're trying to solve is that there are rich teams and there are poor teams. Then there's fifty feet of crap, and then there's us. It's an unfair game. And now we've been gutted. We're like organ donors for the rich. Boston's taken our kidneys, Yankees have taken our heart. And you guys just sit around talking the same old "good body" nonsense like we're selling jeans. Like we're looking for Fabio. We've got to think differently. We are the last dog at the bowl. You see what happens to the runt of the litter? He dies."

"Nick Nolte - Augusto Odone"

"Zack O'Malley Greenburg - Lorenzo Odone"

"Maduka Steady - Omouri"

"Don Suddaby - Himself"

"Do you know how many children die every year from choking on french fries? Many more than from Adrenoleukodystrophy. You see, ours is what is known as an orphan disease, too small to be noticed, too small to be funded, especially with the iron hand of "Reaganomics"."

"Ann Hearn - Loretta Muscatine"

"James Rebhorn - Ellard Muscatine"

"Margo Martindale - Wendy Gimble"

"Gerry Bamman - Doctor Judalon"

"Kathleen Wilhoite - Deirdre Murphy"

"Peter Ustinov - Professor Nikolais"

"Susan Sarandon - Michaela Odone"

"Chris Brochu as Timmy Hamilton"

"Alana Blanchard as Herself (archive footage)"

"Bethany Hamilton as Herself (archive footage)"

"Kristen Steiner as Kaila Kahani"

"Leilani Gryde as Zoe Madsen"

"Bailey Nagy as Olivia Jenner"

"Dutch Hofstetter, Jr. as Brandon"

"Tiffany Hofstetter as Rosemary"

"Nadeen Ayman as Jenny"

"Arlene Newman-Van Asperen as Cydney Blanchard"

"Branscombe Richmond as Ben"

"Cody Gomes as Keoki"

"Craig T. Nelson as Dr. David Rovinsky"

"Sonia Balmores Chung as Malina Birch"

"Jeremy Sumpter as Byron Blanchard"

"Lorraine Nicholson as Alana Blanchard"

"Ross Thomas as Noah Hamilton"