"Look, why don't you go out and bust up a keno game. Do something worthwhile for chrissakes, you two bit vice squad, you're not only dumb, you're dirty."

"John Sibi-Okumu – Dr. Joshua Ngaba"

"Pete Postlethwaite – Dr. Lorbeer / Dr. Brandt"

"I'm dead, Bill. I just want to stay that way for awhile."

"Richard McCabe – Arthur "Ham" Hammond"

"Hubert Koundé – Dr. Arnold Bluhm"

"Danny Huston – Sandy Woodrow"

"Rachel Weisz – Tessa Quayle"

"Bill Nighy – Sir Bernard Pellegrin"

"Archie Panjabi – Ghita Pearson"

"When I agreed to take you back in January I made two suggestions. One was about your drinking. Well, you seem to have licked that. The other was that you curb your talent for creative irresponsibility: you can start working on that right now."

"Ralph Fiennes – Justin Quayle"

"Denzel Washington - Gray Grantham"

"They're a drug company, Arnold. Come on, no drug company does something for nothing."

"Big pharmaceuticals are right up there with the arms dealers."

"Sorry, I've just got one question: Whose map is Britain using when it completely ignores the United Nations and decides to invade Iraq? Or do you think it's more diplomatic to bend to the will of a superpower and politely take part in Vietnam the Sequel?"

"I only give the food to the women, Mr. Black. Women make the homes, men just make wars... and hooch. Adam was God's first draft – He got it right with Eve. Tell that to your readers, Mr. Black."

"Do you no good to go poking around under rocks, Justin. Some very nasty things live under rocks, especially in foreign gardens."

"It's like it's a marriage of convenience and all it produces are dead offspring."

"So who has got away with murder? Not, of course, the British government. They merely covered up, as one does, the offensive corpses. Though not literally. That was done by person or persons unknown. So who has committed murder? Not, of course, the highly respectable firm of KDH Pharmaceutical, which has enjoyed record profits this quarter, and has now licensed ZimbaMed of Harare, to continue testing Dypraxa in Africa. No, there are no murders in Africa. Only regrettable deaths. And from those deaths we derive the benefits of civilization, benefits we can afford so easily... because those lives were bought so cheaply."

"Sam Shepard - Thomas Callahan"

"[on drug trials] Put $50,000 in the right hands and you can test battery acid as skin lotion."

"Vinessa Shaw - Emmy"

"Johnny Whitworth - Tommy Darden"

"Benjamin Petry - Mark Evans"

"Luce Rains - Marshal Weathers"

"Gretchen Mol - Alice Evans"

"Luke Wilson - Zeke"

"Logan Lerman - William Evans"

"Dallas Roberts - Grayson Butterfield"

"Lennie Loftin - Hollander"

"Russell Crowe - Ben Wade"

"Kevin Durand - Tucker"

"Christian Bale - Dan Evans"

"Alan Tudyk - Doc Potter"

"Before the water touches your land, it resides and flows on mine. And as such, I can do with it as I fuckin' please."

"Sometimes a man has to be big enough to see how small he is."

"Peter Fonda - Byron McElroy"

"Railroad's coming, Dan. Your land's worth more with you off it."

"This town's gonna burn!"

"I hate posses."

"Hey. Hey! Not the black hat! The rancher, you dumb-shits! The rancher!"

"[after killing Dan] For a one-leg rancher...[grins] he's one tough son of a bitch!"

"Ben Foster - Charlie Prince"

"Well, would you look at all this? Y'all spared no expense this time, Byron. I gotta say, though, it's probably cheaper just to let me rob the damn thing."

"Well, Tommy... it seems that there was a Pinkerton... inside that coach that wasn't quite dead yet. Now, I know Charlie told you, because... we done got but a few rules in this outfit. And this is what happens when you put us all at risk."

"I ain't never been no hero, Wade. The only battle I seen, we was in retreat. My foot got shot off by one of my own men. You try telling that story to your boy. See how he looks at you then."